Dermatology Flashcards

1
Q

What are the three layers of the skin

A

Epidermis
Dermis
Hypodermis

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2
Q

Name 4 functions of the skin

A

Provide an anatomical barrier
Main method of heat regulation
Sensory input form the body
Storage for lipids and water

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3
Q

What is commensal flora

A

Commensal flora is the normal colonisation that inhibits pathogens in a heathy host

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4
Q

Normal skin has 50 million organisms whereas oily skin has about 500 million organisms.

What re some features of oily skin

A

They have more secretion from the sebaceous glands
The skin tends to become heavier and thicker
They are more at risk of pore blockages and therefore ‘spots and pimples’

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5
Q

What is a comedone

A

A comedone is essentially a blackhead.
It is a feature of acne vulgaris.

It is a build up of keratin and sebum and it turns’ black’ when the blocked pores oxide

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6
Q

What is a furuncle and what organism is it caused by

A

It is an infection of the skin, pockets filled with pus.

The organism involved is staphylococcus aures

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7
Q

If furuncles are grouped together what is this called

A

Carbuncles

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8
Q

Folliculitis is what

A

Furuncle in the hair follicle

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9
Q

What percentage of teenagers aged from 13-18 are affected by acne?

A

80%

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10
Q

What are some causes of acne?

A

Follicular sensitivity to testosterone ( increase around puberty)

Propionibacterium acnes overgrows and leads to infections and cysts

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11
Q

What are some things that can are acne worse

A

Certain contraceptive pills
Greasy skin cleaners
Some anticonvulsant drugs
Squeezing the spots

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12
Q

Acne can be managed locally, how?

A

Reducing excess skin oil - cleanser

Antibacterial agents
- benzoyl peroxide
- antibiotic lotions

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13
Q

If the local treatment of acne fails what other method can be used.

A

Antibiotics can be given - minocylin
Hormone manipulation can be used - anti-androgens

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14
Q

What is erysipelas and what bacteria is it caused by

A

It is a skin infection involving the dermis layer of the skin, defined by a sharp raised border.

Caused by streptococcus pygenes

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15
Q

Erysipelas is managed with systemic antibiotics ( oral or IV)
If this consditon is not managed what can it lead to ?

A

Necrotising fasciitis
Septic shock

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16
Q

Guess the disease

Highly infectious skin disease
Staphylococcal or streptococcal
Crusty red booster appearance
Often associated with eczema

A

Impetigo

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17
Q

How is impetigo treated

A

Often with topical antibiotics (can be systemic)

Antibiotic found from culture

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18
Q

Name 4 bacteria infections of the skin

A

Furuncles
Acne
Erysipelas
Impetigo

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19
Q

Name 4 viral skin infections

A

Herpes simplex
Shingles
Molluscum Contagiosm
Warts

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20
Q

Herpes simplex infection affects single dermatome or adjacent dermatome. How is this infection activated and how is it treated

A

It is activatated by ‘trauma’
- physical, chemical, UV light, run down

It is treated with aciclovir

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21
Q

Shingles is also known as…

A

Herpes zoster infection

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22
Q

Shingle affects a single dermatolome and causes significant pain. How do. We treat this

A

Treat with high dose aciclovir

23
Q

What is molluscum contagiosum, do we treat and who does it usually affect

A

Viral infection of the skin caused by MCV - pox virus
Resolves spontaneously in 1-2 years
Usually affects infants and small. Children

Clusters of smalll papules

24
Q

Human papilloma virus has many types, which types cause warts

A

1 -3

25
Q

HPV a well as causing warts can cause cervical cancer, what types are responsible for this?

A

16 and 18

26
Q

Athletes foot is. Typically a mixed bacterial and fungal infection, how does it present and how do we treate

A

It typically affects in between the toes - groin involvement also common

Scaling and sogginess of the skin
Prevent this by keeping skin clean and dry and damage freee

Treatment — miconazole

27
Q

What is onycholysis?

A

It is a nail bed fungal infection usually tinea unguium infection

The nail becomes thick and malformed and may crumble

28
Q

What condition would unguium be seen in

A

Onycholysis - fungal nail bed infection

29
Q

Despite its name ringworm doesn’t have anything to with worms, it is a fungal skin infection that presents as a red circular rash.
What three areas are commonly affected and what fungi is involved?

A

Groin - tinea Crusis

Body - tinea corporis

Scalp - tinea capittis

30
Q

What is the name of the fungal infection found due to chaffing in moist body folds and how do we treat it

A

Intertrigo

Treat with topical anti fungal cream - miconaazole

31
Q

Pityriasis versicolour results in patchy skin pigmentation and is usually caused by what

A

Pityrosporum orbiculare

Can be seen in cradle cap

32
Q

What are the two skin infestations

A

Scabies
Lice

33
Q

What is scabies caused by

A

Invasion of the scabies mite - sarcoptes scabiei

Skin to skin contact

34
Q

What are the most common signs of scabies

A

Skin rash and itchiness on trunk and limbs

35
Q

Wha is the treatment for scabies

A

Use chemical insecticides
Benzyl Benzoate

Apply to the whole body from chin down

36
Q

What are three types of lice

A

Head
Pubic
Body

37
Q

Name three inflammatory skin diseases

A

Eczema
Occupational dermatitis
Psoriasis

38
Q

Where does eczema most commonly affect?

A

Usually affects FLEXOR surfaces of skin or trunk

39
Q

Atopic eczema is the most common form of eczema, what are some features of it

A

Develops in childhood - usually improves with age
Tends to run n families
Associated with other atopic conditions such as hay fever and asth,a

40
Q

Other than atopic eczema what other kinds can you get

A

Contact - this is when there is contact with an allergen ( perfume soap)

Seborrhoeic - scalp and eyelashes ( serve dandruff )

Discoid - circular patches on the body

Gravitational - related to poor circulate in the legs

41
Q

What are some common triggers of eczema

A

Stress
Menstruation
Illnesss
Weather

42
Q

In eczema management how does a corticosteroids work

A

Removes the inflammation and allows the skin to return to normal

43
Q

What is occupational dermatitis

A

This is a reactio to an environmental agent
That usually results in a rash

44
Q

Psoriasis is an inflammatory skin disease - the cause of which is unknown ( 2% of the population suffer from this)

What is it

A

Dysregualted epidermal proliferation
- new cells produced faster than the old cells are lost
- skim surface builds up and thickens

Red scaly patches that can become itchy

45
Q

There is not one cleat treatment for psoriasis, suggest some methods

A

Initially topical - emollients , topical steroid

PUVA

46
Q

What is PUVA with regards to psoriasis treatment

A

Psoralen UV light A

Topical drug activated by UV light

47
Q

What is the effect of systemic medication such as methotrexate or cicolosporin in psoriasis

A

These drugs reduce the cell turnover

48
Q

What happens in immunological. Skin disease

A

Auto-antibody attack on skin components causing loss of cell-cell adhesion
This causes a split to form in the skin which fills with inflammatory exudate - forming a blister

49
Q

Where does the skin and oral mucosa share many common antigens and epitopes with?

A

Genital mucosa

50
Q

Guess the diesease
-SUB epithelial antibody attach
Thick walled blisters - clear or blood filed

A

Pemphigoid

51
Q

What is pemphigus?

A

A disease causing blistering of the skin, oral mucosa, nose throat eyes and genital

52
Q

What kind of pemphigus affects the oral mucosa

A

Vulgaris

53
Q

What is epidermolysis bullosa and what problems can it cause

A

This is a group of conditions which cause the skin to blister easily

It can cause infection fluid loss and scarring