DERMATOLOGY

Question 1

Derm manifestations of IBD + appearance?

Answer 1

Pyoderma gangrenosum: begin as pustules, eroding and ulceration, central necrotic tissue DOESN’T ALWAYS CORRELATE WITH DISEASE ACTIVITY

Sweets: raised tender nodules (face, arm, trunk), neutrophils infiltration

Erythema nodosum: painful nodules on anterior legs/hands CORRELATE WITH BOWEL ACTIVITY

Psoriasis

Question 2

Derm manifestations of RA + appearance?

Answer 2

Pyoderma gangrenosum: begin as pustules, eroding and ulceration, central necrotic tissue

Rheumatoid nodules

Neutrophilis dermatoses

Question 3

Derm manifestations of Coeliac + appearance?

Answer 3

Dermatitis herpetiformis
- itchy purpuric papules/vesicles/ bullae on extensor surfaces
- tx: dapsone, gluten free diet, sulfasalazine, colchicine

Atrophic glossitis

Question 4

Derm manifestations of DM + appearance?

Answer 4

Acanthosis nigricans
Mucormycosis: black fungus sinusitis
Diabetic dermopathy (appa’s leg)
Diabetic bullae
Stiff skin
Granuloma annulare
Eruptive xanthoma
Vitiligo
Necoviosis lipodica: yellow waxy plaques

Question 5

Derm manifestations of HIV?

Question 6

Erythema nodosum associations?

Answer 6

IBD
sarcoidosis
Infection: strep/staph
Malignancy
Behcets
Drugs: penicillins. sulphonamides, COCP

Question 7

Tx for neutrophilic dermatoses?

Answer 7

DO NOT DEBRIDE = gets worse

Steroids

Question 8

SLE derm changes?

Answer 8

Acute, subacute cutaneous LE (photosensitive, malar, maculopapular, bullous)
- Butterly rash: photosensitive, lightly raised, occ scaly erythema
- Spares nasolabial folds
- Generalised diffuse erythema

Subacute
- Annular/papulosquamous/both
- Photosensitive
- Infrequent scarring, hyper-hypopigmentation can occur

Chronic cutaneous LE (discoid lupus, panniculitis, lichen planus-like, hypertrophic verrucous, chillblains) - RO-52 associated
- Discoid: slightly raised, scaly hyperpigmented erythematous rims and depigmented, atrophic centers
- Scarring can occur
- Increased risk of systemic lupus, FBE abnormalities, positive ANA

Oral or nasal ulcers
Nonscarring Alopecia
- Diffuse
- Related to disease activity
Chillblain’s
Panniculitis

Question 9

Sarcoid derm changes?

Answer 9

• Maculopapular lesions
  • Hyper/hypopigmentation
  • Keloid
  • Subcutaneous nodules
  • erythema nodosum
  • skin: lupus pernio
    ○ Rash on face
  • Papules on nose bridge/ area beneath eyes/ cheeks