Dermatology Flashcards

1
Q

What is eczema

A

Chronic atopic condition

Inflammation in skin

Tends to run in families

Usually presents in infancy

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2
Q

How might a patient with eczema present

A

Dry, red, itchy, sore patches of skin

On flexor surfaces, face, and neck

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3
Q

What is the maintenance management for eczema

A

Emollients (artificial barrier over skin)

Soap substitutes

Avoid environmental triggers

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4
Q

What is the management for eczema flares

A

Thicker emollients

Topical steroids

Antibiotics (rarely needed)

Zinc impregnated bandages

Phototherapy

Systemic immunosuppressants (corticosteroids, methotrexate)

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5
Q

What is eczema herpecticum

A

Viral infection of skin

Due to: herpes simplex, varicella zoster

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6
Q

How might a patient with eczema herpecticum present

A

Widespread, painful, vesicular rash

Fever

Lethargy

Irritability

Reduced oral intake

Lymphadenopathy

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7
Q

What are the investigations for eczema herpecticum

A

Viral swab of vesicles

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8
Q

What is the management for eczema herpecticum

A

Aciclovir (IV in severe cases)

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9
Q

What are the complications of eczema herpecticum

A

Can be life threatening if not treated properly

Can get bacterial superinfection

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10
Q

What is psoriasis

A

Chronic autoimmune condition

Recurrent psoriatic skin lesions

Skin dry, flaky, scaly, slightly erythematous

Raised and rough plaques

Over extensor surfaces

Due to rapid generation of new skin cells

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11
Q

What are the types of psoriasis

A

Plaque (most common form)

Guttate (mostly in children, triggered by strep throat infection)

Pustular (can be systemically unwell, medical emergency)

Erythrodermic (skin can come away in large patches, medical emergency)

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12
Q

How might a patient with psoriasis present

A

Auspitz sign: small points of bleeding when plaques scraped off

Koebner phenomenon: psoriatic lesions to areas of skin affected by trauma

Residual pigmentation (after lesions resolve)

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13
Q

What is the management for psoriasis

A

Topical steroids

Topical vitamin D analogues

Topical dithranol

Phototherapy

Systemic treatment (methotrexate, cyclosporin)

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14
Q

What are the complications of psoriasis

A

Nail psoriasis (pitting, thickening, discolouration, ridging, separation from bed)

Psoriatic arthritis

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15
Q

What is acne vulgaris

A

During puberty and adolescence

Chronic inflammation of pilosebaceous units under skin

Due to: increased production of sebum, trapping of keratin, blockage of pilosebaceous unit

Exacerbated by androgenic hormones

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16
Q

How might a patient with acne vulgaris present

A

Macules (flat marks on skin)

Papules (small lumps on skin)

Pustules (small lumps containing yellow pus)

Comedones (blocked pilosebaceous units)

Black heads (open comedones with black pigmentation)

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17
Q

What is the management for acne vulgaris

A

Topical benzoyl peroxide (reduced inflammation, unblocks skin)

Topical retinoids (slow production of sebum, highly teratogenic)

Topical/oral antibiotics

COCP

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18
Q

What is first disease

A

Measles

Highly contagious

Symptoms 10-12 days after exposure

Presentation: fever, coryza, conjunctivitis, koplik spots (grey white spots on buccal mucosa)

Rash starts on face, spreads to rest of the body

Self resolves in 7-10 days

Notifiable disease

Complications: pneumonia, diarrhoea, dehydration, encephalitis, meningitis, hearing loss, death

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19
Q

What is 2nd disease

A

Scarlet fever

Due to group A strep

Pink, blotchy, macular rash

Rough ‘sandpaper’ skin

Starts on trunk, spreads outwards

Presentation: fever, lethargy, flushed face, sore throat, strawberry tongue, cervical lymphadenopathy

Antibiotics (penicillin V)

Notifiable disease

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20
Q

What is 3rd disease

A

Rubella

2 week incubation

Erythematous, macular rash

Starts on face, spreads to body

Presentation: mild fever, joint pains, sore throat, lymphadenopathy

Notifiable disease

Should stay off school for 5 days from rash starting, and away from pregnant women

Complications: thrombocytopenia, encephalitis, congenital rubella syndrome (deafness, blindness, congenital heart disease)

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21
Q

What is 4th disease

A

Duke’s disease

Non-specific viral rash

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22
Q

What is 5th disease

A

Slapped cheek syndrome

Parvovirus B19 infection

Affects trunk and limbs

Self resolves in 1-2 weeks

Complications: aplastic anaemia, encephalitis, meningitis, pregnancy complications, hepatitis, myocarditis, nephritis

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23
Q

What is 6th disease

A

Roseola infantum

Due to herpesvirus 6

1-2 week incubation

High fever for 3-5 days, disappears suddenly

Coryzal symptoms

Rash 1-2 days after fever

Rash on arms, legs, face, trunk (not itchy)

Fully recover in a week

Complications: febrile convulsions

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24
Q

What is erythema multiforme

A

Erythematous rash due to hypersensitivity reaction

Mostly due to viruses or medications

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25
Q

How might a patient with erythema multiforme present

A

Widespread, itchy, erythematous rash

Characteristic target lesions

Can cause stomatitis

Mild fever

Muscle and joint pains

Headache

Flu-like symptoms

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26
Q

What is the management for erythema multiforme

A

Resolves spontaneously in 1-4 weeks

If severe: IV fluids, analgesia, steroids

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27
Q

What is urticaria

A

Aka hives

Small, itchy lumps on skin

Can be associated with angioedema and flushed skin

Due to release of histamines by mast cells

Can be acute or chronic

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28
Q

What are the causes of urticaria

A

Food allergies

Medication allergies

Animal allergies

Contact with chemicals

Viral infections

Insect bites

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29
Q

What is the management for urticaria

A

Antihistamines (fexofenadine)

Oral steroids

30
Q

What are chicken pox

A

Due to varicella zoster virus

Generalised vesicular rash

Highly contagious

Incubation 10-21 days

Stop being contagious when lesions have crusted over

31
Q

How might a patient with chicken pox present

A

Widespread, erythematous, raised, vesicular blistering lesions

Starts on trunk or face, then spreads

Fever

Itching

Generalised fatigue and malaise

32
Q

What is the management for chicken pox

A

Usually mild and self limiting

Aciclovir (immunocompromised, adults, neonates)

Calamine lotion/antihistamines for itching

Children should stay off school and away from pregnant women

33
Q

What are the complications of chicken pox

A

Bacterial superinfection

Dehydration

Conjunctival lesions

Pneumonia

Encephalitis

Shingles

Ramsay Hunt syndrome

34
Q

What is hand, foot and mouth disease

A

Due to coxsackie A virus

3-5 day incubation

35
Q

How might a patient with hand, foot and mouth disease present

A

Viral upper respiratory tract infections

After 1-2 days, small mouth ulcers

Blistering red spots across body

Spots most noticeable on hands, feet and mouth

Can be itchy

36
Q

What is the management for hand, foot and mouth disease

A

No treatment

Resolves in 10 days

Supportive management

37
Q

What are the complications of hand, foot and mouth disease

A

Dehydration

Bacterial superinfection

Encephalitis

38
Q

What is molluscum contagiosum

A

Due to poxvirus

Direct contact spread

39
Q

How might a patient with molluscum contagiosum present

A

Rash

Small, flush-coloured papules

Have central dimpling

Appear in crops

40
Q

What is the management for molluscum contagiosum

A

Spontaneously resolves (can take 18 months for papules to disappear)

Antibiotics if have bacterial superinfection

Surgical removal of papules

41
Q

How might a patient with pityriasis rosea present

A

Characteristic herald patch rash

Faint red, scaly, oval lesions

Usually on torso

Follow lines of ribs

General flu-like symptoms

42
Q

What is the management for pityriasis rosea

A

Usually resolves in 3 months

Not contagious (can carry on with normal activity)

43
Q

What is seborrhoeic dermatitis

A

Inflammatory skin condition affecting sebaceous glands

Can cause cradle cap

Due to malassezia yeast

44
Q

What is infantile seborrhoeic dermatitis

A

Cradle cap

Crusty, flaking skin

Usually resolves by 4 months

Management: baby oil, white petroleum jelly, anti-fungal creams

45
Q

What is seborrhoeic dermatitis of the scalp

A

Get dandruff

Management: ketoconazole shampoo, topical steroids

46
Q

What is ringworm

A

Fungal infection of skin

Aka tinea

47
Q

How might a patient with ringworm present

A

Itchy, erythematous, scally, demarcated rash

Ring shaped area, spreads outwards

48
Q

What is the management for ringworm

A

Antifungal creams/shampoos

Oral antifungals

Advice: wear loose clothing, keep area clean and dry, avoid sharing towels, avoid scratching and spreading to other areas

49
Q

What is nappy rash

A

Contact dermatitis in nappy area

Due to: friction between skin and nappy, contact with urine and faeces

Most common at 9-12 months

50
Q

What are the risk factors for nappy rash

A

Delayed nappy changing

Irritant soaps

Vigorous cleaning

Certain types of nappies (poorly absorb)

Diarrhoea

Oral antibiotics

Pre-term babies

51
Q

What is the management for nappy rash

A

Switch to highly absorbent nappies

Change nappies asap

Water or gentle products for cleaning

Make sure area dry before putting nappy on

Maximise time not wearing a nappy

52
Q

What are the complications of nappy rash

A

Candida infection

Cellulitis

Erosion or ulceration of skin

53
Q

What are scabies

A

Mites that burrow under skin

Cause skin infection and intense itching

Up to 8 weeks before rash appears

54
Q

How might a patient with scabies present

A

Itchy, small red spots

Possible track marks (usually between fingers)

55
Q

What is the management for scabies

A

Permethrin cream (cover whole body, leave for 8-12 hours then wash off, repeat after 1 week)

56
Q

What is the management for headlice

A

Dimeticone 4% lotion: leave on for 8 hours, wash off, repeat in 1 week

Fine comb (systemically comb lice out)

57
Q

What are the differentials for a non-blanching rash

A

Meningococcal septicaemia

Henoch-Schonlein purpura

Idiopathic thrombocytopenic purpura

Acute leukaemia

Haemolytic uraemic syndrome

Viral illness

58
Q

What are the investigations for non-blanching rashes

A

Bloods

Blood cultures

Lumbar puncture

Blood pressure

Urine dip

59
Q

What is erythema nodosum

A

Red lumps on shins

Due to inflammation of subcutaneous fat

A hypersensitivity reaction

Causes: streptococcal throat infection, gastroenteritis, mycoplasma pneumonia, TB, pregnancy, medications (COCP, NSAIDs), inflammatory bowel disease, sarcoidosis, lymphoma, leukaemia

60
Q

What are the investigations for erythema nodosum

A

Bloods

Throat swab

Chest X-ray

Stool microscopy and culture

Faecal calprotectin

61
Q

What is the management for erythema nodosum

A

Rest and fluids

Consider steroids

Most resolve in 6 weeks

62
Q

What is impetigo

A

Superficial bacterial skin infection

Usually due to staph aureus

Get a ‘golden crust’ appearance

Contagious (keep off school)

Non-bullous: around nose and mouth, treat with topical fusidic acid, antiseptic cream, oral flucloxacillin

Bullous: in < 2s, fever and generally unwell, treat with flucloxacillin

63
Q

What are the complications of impetigo

A

Cellulitis

Sepsis

Scarring

Post-streptococcal glomerulonephritis

Staph scalded skin syndrome

Scarlet fever

64
Q

What is staphylococcal scalded skin syndrome

A

Staph aureus that produces epidermolytic toxins (protease enzymes)

Usually in < 5s

65
Q

How might a patient with staphylococcal scalded skin syndrome present

A

Generalised patches of erythema on skin

Skin becomes thin and wrinkled

Formation of bullae (burst and leave sores, erythematous skin below)

Nikolsky sign: gently rubbing skin causes it to peel away

66
Q

What is the management for staphylococcal scalded skin syndrome

A

IV antibiotics

67
Q

What is Steven-Johnson syndrome

A

Disproportionate immune response causes epidermal necrosis

Blistering and shedding of top layer of skin

68
Q

What are the causes of Steven-Johnson syndrome

A

Medications: anti-epileptics, antibiotics, allopurinol, NSAIDs

Infections: herpes, mycoplasma pneumoniae, cytomegalovirus, HIV

69
Q

How might a patient with Steven-Johnson syndrome present

A

Fever, cough, sore throat, sore mouth, sore eyes, itchy skin

Purple/red rash spreading across skin

Skin starts to blister

Skin breaks away and leaves raw tissue underneath

70
Q

What is the management for Steven-Johnson syndrome

A

Supportive care

Steroids

Immunoglobulins

Immunosuppressants

71
Q

What are the complications of Steven-Johnson syndrome

A

Secondary infection

Permanent skin damage

Visual compromise