Dermatology Flashcards

1
Q

Benzoyl Peroxide - How to use it

A

Apply to skin 1-2 times a day, preferably after washing with soap and water, and start treatment with lower-strength preparations.

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2
Q

Benzoyl Peroxide - Caution & Contraindication

A

Caution and contraindications:

  • Hypersensitivity to the active substance or to any of the excipients.
  • Avoid contact with broken skin, eyes, mouth and mucous membranes
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3
Q

Benzoyl Peroxide - Side Effects

A
  • Skin irritation (dryness, discomfort, erythema, peeling and blistering) - reduce frequency or stop use until irritation settles then re-introduce at reduced concentration or frequency.
  • Allergic contact dermatitis to benzoyl peroxide — consider if itching and swelling of the eyes occurs.
  • Increased risk of sunburn — if sun exposure is unavoidable, an appropriate sunscreen or protective clothing should be used.
  • May bleach fabrics and hair.
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4
Q

Benzoyl Peroxide - Combination with other drugs

A
  • Usually combined with topical antibiotic (e.g., Duac)
  • ->If two separate products are used, they should be applied 12 hours apart. Benzoyl peroxide at night and the topical antibiotics in the morning.
  • Could also be combined with topical retinoid. Especially in maintenance of acne
  • -> Apply once daily, 12 hours apart. Topical retinoid at night and benzoyl peroxide in the morning.
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5
Q

Topical Retinoids - Indication

A

Acne

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6
Q

Topical Retinoids - Examples

A

Adapalene and tretinoin

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7
Q

Topical Retinoids - Side Effects

A
  • Skin irritation: discomfort, blistering of skin, burning, crusting, dryness, peeling, erythema, oedema, pruritus, stinging, contact dermatitis and temporary changes of skin pigmentation.
  • Eye irritation.
  • Increased sensitivity to UV light
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8
Q

Topical Retinoids - Contraindication & Caution

A
  • Hypersensitivity to the active substance or to any of the excipients.

Avoid in:

  • Pregnancy and breastfeeding
  • Severe acne, perioral dermatitis, rosacea or a personal or family history of non-melanoma skin cancer.
  • Accumulation in angles of the nose and contact with eyes, nostrils, mouth and mucous membranes, eczematous, broken or sunburned skin.
  • Exposure to excess UV light (including sunlight and solariums)
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9
Q

Topical Retinoids - How to use it

A
  • Once daily or twice daily depending on agent used.
  • Used sparingly and not just on visible spots
    If the person has sensitive skin, initiate therapy
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10
Q

Topical Retinoids - Interactions

A
  • Systemic absorption may follow topical application of isotretinoin and prescribers should be aware of the possibility of interactions
  • Other retinoids or drugs with a similar mode of action should not be used concurrently.
  • Avoid use of topical retinoids with abrasive cleaners, comedogenic or astringent cosmetics.
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11
Q

Topical Antibiotics - Examples

A

.

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12
Q

Topical Retinoids - Indication

A

Acne

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13
Q

Topical Retinoids - Examples

A

Adapalene and tretinoin

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14
Q

Topical Retinoids - Side Effects

A
  • Skin irritation: discomfort, blistering of skin, burning, crusting, dryness, peeling, erythema, oedema, pruritus, stinging, contact dermatitis and temporary changes of skin pigmentation.
  • Eye irritation.
  • Increased sensitivity to UV light
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15
Q

Topical Retinoids - Contraindication & Caution

A
  • Hypersensitivity to the active substance or to any of the excipients.

Avoid in:

  • Pregnancy and breastfeeding
  • Severe acne, perioral dermatitis, rosacea or a personal or family history of non-melanoma skin cancer.
  • Accumulation in angles of the nose and contact with eyes, nostrils, mouth and mucous membranes, eczematous, broken or sunburned skin.
  • Exposure to excess UV light (including sunlight and solariums)
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16
Q

Topical Retinoids - How to use it

A
  • Once daily or twice daily depending on agent used.
  • Used sparingly and not just on visible spots
    If the person has sensitive skin, initiate therapy
17
Q

Topical Retinoids - Interactions

A
  • Systemic absorption may follow topical application of isotretinoin and prescribers should be aware of the possibility of interactions
  • Other retinoids or drugs with a similar mode of action should not be used concurrently.
  • Avoid use of topical retinoids with abrasive cleaners, comedogenic or astringent cosmetics.
18
Q

Topical Antibiotics - Examples

A

.