Dermatological Pharm

Question 1

Creams

Answer 1

wet skin conditions

Question 2

Ointments

Answer 2

dry skin conditions

Question 3

PABA

Answer 3

for UVB range

Question 4

Dibenzoylmethanes

Answer 4

for UVA range

Question 5

Chlorhexidine

Answer 5

broad spectrum antispetic

Question 6

Becaplermin

Answer 6

A growth factor for Diabetic Foot Ulcers

Question 7

Bacitracin

Answer 7

inhibits bacterial cell wall synthesis

Question 8

Neomycin

Answer 8

binds to ribosome 30S

Question 9

Polymixin B

Answer 9

binds phospholipids, alters permeability

Question 10

Miconazole, Clotrimazole

Answer 10

Blocks Ergosterol Synthesis –> VULVOVAGINAL Candidias

Question 11

Efinaconazole

Answer 11

Blocks Ergosterol Synthesis –> Onchymycosis

Question 12

Ketoconazole

Answer 12

Blocks Ergosterol Synthesis –> Dermatophytes/Candida infections of the scalp (dandruff)

Question 13

Ciclopirox

Answer 13

disrupts macromolecular synthesis –> for D. C. M

Question 14

Terbinafine

Answer 14

inhibits squalene epoxidase –> for D

Question 15

Tolnaftate

Answer 15

Distorts hyphae growth –> D, M

Question 16

Nystatin

Answer 16

alters membrane permeability –> for oral candida

Question 17

Amphotericin B

Answer 17

alters membrane permeability –> Skin Candida / Serious infections

Question 18

Acyclovir

Answer 18

synthetic guanine analog –> HSV1/2

Question 19

Topical Calcineurin Inhibitor

Answer 19

for anogenital pruritus

Question 20

Pramoxine

Answer 20

pruritus on face

Question 21

Lidocaine

Answer 21

Neuropathic Itch

Question 22

Capsaicin

Answer 22

(heat) for neuropathic itch

Question 23

Mirtazapine

Answer 23

alpha 2 antagonist –> for nocturnal itch

Question 24

sertraline

Answer 24

SSRI –> for cholestatic itch

Question 25

Paroxetine/Fluvoxamine

Answer 25

SSRI --> for psych pts with itch

Question 26

Naltrexone

Answer 26

Opioid antag --> CKD itch

Question 27

Butorphanol

Answer 27

Mixed Opioid antag/agonist --> nocturnal/intractable itch

Question 28

Gabapentin

Answer 28

GABA --> neuropathic itch

Question 29

Aprepitant

Answer 29

Sub P antag --> Sezary Syndrome

Question 30

Malathion

Answer 30

organophosphate cholinesterase inhibitor

Question 31

Permethrin

Answer 31

binds to insect Na channels (blocks repolarization)

Question 32

Ivermectin

Answer 32

binds to glu-gated cl channels

Question 33

Lindane

Answer 33

disrupts GABA transmission

Question 34

Topical Retinoids

Answer 34

for Acne Vulgaris

Question 35

Benzoyl Peroxide

Answer 35

topical antimicrobials

Question 36

Apremilast

Answer 36

Inhibits PDE4 --> mod/severe plaque psoriasis, p arthritis

Question 37

Ustekinumab

Answer 37

Targets Il-12/23 --> "psoriasis" and Chrons

Question 38

Secukinumab

Answer 38

Targets Il-17a --> "Psoriasis" and Ankylosing Spondylitis

Question 39

Topical 5-FU

Answer 39

for Actinic Keratoses

Question 40

Minoxidil

Answer 40

vasodilator due to K channel opening --> male pattern baldness/Female Pattern Hair Loss

Question 41

Finasteride

Answer 41

inhibitor of DHT --> male pattern baldness | 2nd line female pattern hair loss

Question 42

Diphenylcyclopropene

Answer 42

Alopecia Atreata