Dermatological Pharm Flashcards

1
Q

Creams

A

wet skin conditions

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2
Q

Ointments

A

dry skin conditions

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3
Q

PABA

A

for UVB range

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4
Q

Dibenzoylmethanes

A

for UVA range

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5
Q

Chlorhexidine

A

broad spectrum antispetic

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6
Q

Becaplermin

A

A growth factor for Diabetic Foot Ulcers

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7
Q

Bacitracin

A

inhibits bacterial cell wall synthesis

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8
Q

Neomycin

A

binds to ribosome 30S

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9
Q

Polymixin B

A

binds phospholipids, alters permeability

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10
Q

Miconazole, Clotrimazole

A

Blocks Ergosterol Synthesis –> VULVOVAGINAL Candidias

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11
Q

Efinaconazole

A

Blocks Ergosterol Synthesis –> Onchymycosis

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12
Q

Ketoconazole

A

Blocks Ergosterol Synthesis –> Dermatophytes/Candida infections of the scalp (dandruff)

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13
Q

Ciclopirox

A

disrupts macromolecular synthesis –> for D. C. M

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14
Q

Terbinafine

A

inhibits squalene epoxidase –> for D

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15
Q

Tolnaftate

A

Distorts hyphae growth –> D, M

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16
Q

Nystatin

A

alters membrane permeability –> for oral candida

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17
Q

Amphotericin B

A

alters membrane permeability –> Skin Candida / Serious infections

18
Q

Acyclovir

A

synthetic guanine analog –> HSV1/2

19
Q

Topical Calcineurin Inhibitor

A

for anogenital pruritus

20
Q

Pramoxine

A

pruritus on face

21
Q

Lidocaine

A

Neuropathic Itch

22
Q

Capsaicin

A

(heat) for neuropathic itch

23
Q

Mirtazapine

A

alpha 2 antagonist –> for nocturnal itch

24
Q

sertraline

A

SSRI –> for cholestatic itch

25
Q

Paroxetine/Fluvoxamine

A

SSRI –> for psych pts with itch

26
Q

Naltrexone

A

Opioid antag –> CKD itch

27
Q

Butorphanol

A

Mixed Opioid antag/agonist –> nocturnal/intractable itch

28
Q

Gabapentin

A

GABA –> neuropathic itch

29
Q

Aprepitant

A

Sub P antag –> Sezary Syndrome

30
Q

Malathion

A

organophosphate cholinesterase inhibitor

31
Q

Permethrin

A

binds to insect Na channels (blocks repolarization)

32
Q

Ivermectin

A

binds to glu-gated cl channels

33
Q

Lindane

A

disrupts GABA transmission

34
Q

Topical Retinoids

A

for Acne Vulgaris

35
Q

Benzoyl Peroxide

A

topical antimicrobials

36
Q

Apremilast

A

Inhibits PDE4 –> mod/severe plaque psoriasis, p arthritis

37
Q

Ustekinumab

A

Targets Il-12/23 –> “psoriasis” and Chrons

38
Q

Secukinumab

A

Targets Il-17a –> “Psoriasis” and Ankylosing Spondylitis

39
Q

Topical 5-FU

A

for Actinic Keratoses

40
Q

Minoxidil

A

vasodilator due to K channel opening –> male pattern baldness/Female Pattern Hair Loss

41
Q

Finasteride

A

inhibitor of DHT –> male pattern baldness

2nd line female pattern hair loss

42
Q

Diphenylcyclopropene

A

Alopecia Atreata