Dermatological Drugs Flashcards

1
Q

What is bacitracin?

A

Bacitracin is a common topical antibacterial drug

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2
Q

What is neomycin?

A

Neomycin is a common topical antibacterial drug.

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3
Q

What is polymyxin?

A

Polymyxin is a common topical antibacterial drug. It is often combined with neomycin as neomycin and polymyxin B (Neosporin).

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4
Q

What is mupirocin (Bactroban) used for? What is a growing concern regarding its use?

A

Mupirocin (Bactroban) is a topical antibacterial used for Staphylococcus and Streptococcus impetigo. It is also applied topically three times daily to treat MRSA. However, due to the high incidence of MRSA, mupirocin is now becoming resistant. It is available by prescription.

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5
Q

What is silver sulfadiazine (Flamazene®) used for? What are its adverse effects and contraindications?

A

Silver sulfadiazine (Flamazene®) is a topical anti-infective used to prevent or treat infection at the site of second- and third-degree burns. Adverse effects include pain, burning, and itching. It should not be used for patients who are allergic to sulfonamide medications.

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6
Q

What is clotrimazole (Canesten®) used for? What formulations are available?

A

Clotrimazole (Canesten®) is a topical antifungal drug. It has many topical formulations and is available as vaginal tablets or cream for yeast infections. It treats many different fungal infections

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7
Q

What is miconazole nitrate (Micantin®, Micozole®, Monistat®) used for? What formulations are available?

A

Miconazole nitrate (Micantin®, Micozole®, Monistat®) is a topical antifungal drug. It is available as a topical cream, and as a cream in prefilled applicators or suppository (ovules). It is used for athlete’s foot, “jock itch,” and yeast infections.

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8
Q

What is acyclovir (Zovirax®) used to treat? Does it cure the infection? What are common adverse effects?

A

Acyclovir (Zovirax®) is a topical antiviral drug used to treat initial and recurrent herpes simplex 1 and 2 and human papillomavirus infections. It does not cure viral skin infections but may reduce healing time and pain. Common adverse effects are stinging, itching, and rash.

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9
Q

What are lidocaine and prilocaine used for topically? What is an example of a combination product?

A

Lidocaine and prilocaine are used topically as local anaesthetics to reduce pain or pruritus associated with insect bites, sunburn, and poison ivy exposure, and to numb the skin before a painful injection. EMLA® is a combination product containing lidocaine and prilocaine.

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10
Q

What are examples of topical antihistamines used for?

A

Topical antihistamines are a category of topical antipruritic drugs used for itching.

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11
Q

What are topical corticosteroids used for?

A

Topical corticosteroids are a category of topical antipruritic drugs used for itching. They also have anti-inflammatory effects, antipruritic effects, and vasoconstrictive actions.

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12
Q

What is etanercept (Enbrel®)?

A

Etanercept (Enbrel®) is an example of an antipsoriatic medication.

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13
Q

What is adalimumab (Humira®)?

A

Adalimumab (Humira®) is an example of an antipsoriatic medication.

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14
Q

What is methotrexate?

A

Methotrexate is an example of an antipsoriatic medication.

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15
Q

What is ustekinumab (Stelara®)?

A

Ustekinumab (Stelara®) is an example of an antipsoriatic medication.

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16
Q

What is crotamiton (Eurax®) used to treat?

A

Crotamiton (Eurax®) is a topical ectoparasiticidal medication used to treat pediculosis (pubic lice, body lice, head lice) and scabies.

17
Q

What is dimeticone 50% (NYDA®) used to treat?

A

Dimeticone 50% (NYDA®) is a topical ectoparasiticidal medication used to treat pediculosis (head lice).

18
Q

What is minoxidil (Rogaine®) used for? Who can use it?

A

Minoxidil (Rogaine®) is a topical hair growth drug for men and women.

19
Q

What is finasteride (Propecia®) used for? What are important considerations for women regarding this medication?

A

Finasteride (Propecia®) is a systemic hair growth drug. It is not to be taken during pregnancy, and women are not to handle this medication without gloves nor to crush it.

20
Q

What is fluorouracil (Efudex®) used for?

A

Fluorouracil (Efudex®) is a topical antineoplastic used for premalignant skin lesions and basal cell carcinoma, and for actinic keratosis.

21
Q

What is pimecrolimus (Elidel®) used to treat? What other drug has similar actions?

A

Pimecrolimus (Elidel®) is an immunomodulator used to treat atopic dermatitis. Topical tacrolimus (Protopic®) has similar actions.

22
Q

What is imiquimod (Aldara P®, Vyloma®) used to treat?

A

Imiquimod (Aldara P®, Vyloma®) is an immunomodulator used to treat actinic keratosis, basal cell carcinoma, and anogenital warts.

23
Q

What is used in wound care?

A

Vitamin C (ascorbic acid), zinc, sodium hypochlorite (Dakin’s solution), iodine (Locidedosorb®), acetic acid (vinegar) is used in wound care.

Also Collagenase (Santyl®) is a topical wound care medication that promotes wound healing as a débriding drug.

24
Q

What is isopropyl alcohol (70%) used for?

A

Isopropyl alcohol (70%) is a skin preparation drug.

25
What is povidone-iodine (Betadine®) used for?
Povidone-iodine (Betadine®) is a skin preparation drug.
26
What is chlorhexidine (Dexidin®, Hibitane®) used for?
Chlorhexidine (Dexidin®, Hibitane®) is a skin preparation drug.
27
What is benzalkonium chloride (Agentquat®) used for?
Benzalkonium chloride (Agentquat®) is a skin preparation drug.
28
Functions of the skin
- Protective barrier for internal organs - sensing changes in temperature, pressure, and pain - regulating body temp. - excreting fluids and electrolytes - storing fat - synthesizing vitamin D - site for drug absorption
29
Most common bacteria in skin infection
The most common bacteria involved in skin infections are Streptococcus pyogenes and Staphylococcus aureus. These bacteria can cause conditions like folliculitis, impetigo, furuncles, carbuncles, cellulitis, pustules, vesicles, and papules.
30
Why can topical fungal infections be difficult to treat, and how long might therapy last?
Topical fungal infections can be difficult to eradicate, and therapy may be prolonged, lasting from several weeks to 1 year.
31
Name two common causes of topical fungal infections.
Two common causes of topical fungal infections are Candida albicans, a yeastlike opportunistic fungus, and dermatophytes, which cause tinea or ringworm infections. Malassezia furfur also causes tinea versicolour.
32
What are some potential adverse effects and drug interactions associated with topical use of aloe?
Adverse effects of topical aloe use can include dermatitis. Drug interactions can occur with digoxin, antidysrhythmics, diuretics, and corticosteroids.
33
What patient teaching points are important regarding topical dermatological medications?
Important patient teaching includes the need to protect the affected area from sunlight, to not double up on doses if a dose is missed, to ensure proper disposal of contaminated dressings, and information necessary for the patient’s self-care. Nurses should also monitor therapeutic responses and adverse effects.