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Pharmacology 3805 > Dermatological Drugs > Flashcards

Dermatological Drugs Flashcards

1
Q

Bacitracin and Gramicidin treat gram + or gram - strains?

A

Gram +

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2
Q

What are examples of bacteria that bacitracin and gramicidin antibacterials can treat?

A

-Streptococci
-pneumococci
-staphylocci

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3
Q

Mupirocin antibacterials treat gram + or gram - strains?

A

Gram +

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4
Q

What are examples of bacterial strains that Mupirocin can treat?

A

-Staphylococcus aureus including MRSA

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5
Q

What are some examples of bacterial strains that Retapamulin can treat?

A

Streptococci and Staph. aureus (NOT MRSA)

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6
Q

Does Polymyxin B Sulfate treat gram - or gram + bacteria?

A

Gram -

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7
Q

What are some examples of bacterial strains that Polymyxin B Sulfate can treat?

A

Pseudomonas aeruginosa
E.Coli

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8
Q

Does Neomycin and Gentamicin treat against gram - or gram + bacterial strains?

A

Gram -

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9
Q

What does bacteria does Clindamycin treat?

A

Propionibacterium acnes (gram +)

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10
Q

What does Erythromycin treat?

A

P.acnes

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11
Q

What does Sodium Sulfacetamide treat?

A

P.acnes

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12
Q

What does Metronidazole treat?

A

Demodex brevis

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13
Q

What are 5 known antibiotics?

A

-Clindamycin
-Erythromycin
-Sodium Sulfacetamide
-Dapsone
-Metronidazole

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14
Q

What are 4 examples of topical antivirals?

A

-Acyclovir
-Valcyclovir
-Penicyclovir
-Famicyclovir

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15
Q

What are 6 examples of ectoparasiticides?

A

-Permethrin
-Lindane (hexachlorocyclohexane)
-Crotamiton
-Sulfur
-Malathion
-Benzyl Alcohol

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16
Q

What does Permethrin treat?

A

Mites

17
Q

What does Lindane treat?

A

Lice

18
Q

What does Crotamiton treat?

A

Scabies

19
Q

What does Benzyl Alcohol treat?

A

head lice

20
Q

What are 4 acne preparations you should know?

A

-Retinoic acid and derivatives
-Isotretinoin
-Benzoyl Peroxide
-Azelaic Acid

21
Q

What acne preparation is essentially “acidic vitamin A”?

A

Retinoic acid

22
Q

What acne preparation is an analogue of vitamin A?

A

Isotretinoin

23
Q

What pro-inflammatory cytokines are released during psoriasis?

A

-IFN- gamma
-IL-23
-IL-17
-IFN- Alpha

24
Q

What are the 4 drugs used for treating psoriasis?

A

-Acitretin
-Tazarotene
-Calcipotriene
-Calcitriol

25
Q

What drugs for psoriasis are retinoids, and vitamin A derivatives?

A

-Acitretin
-Tazarotene

26
Q

What drugs for psoriasis are related to Vitamin D?

A

-Calcipotriene
-Calcitriol

27
Q

What biologics are used to treat psoriasis?

A

-Alefacept
-TNF Inhibitors (Etanercept, Infliximab, Adalimumab)
-Ustekinumab (IgG antibody)

27
Q

What biologics are used to treat psoriasis?

A

-Alefacept
-TNF Inhibitors (Etanercept, Infliximab, Adalimumab)
-Ustekinumab (IgG antibody)

28
Q

Are biologic agents naturally occurring or are they synthetically made?

A

Naturally occuring

29
Q

What effect does Alefacept have on the immune system?

A

-It is an immunosuppressant
-Stops the activity of T lymphocytes

30
Q

How is Alefacept administered?

A

Intramuscularly

31
Q

How does Etanercept work?

A

It acts as a decoy receptor for TNF-Alpha. Etanercept receptors will become saturated so normal TNF-Alpha receptors do not. Thus, decreasing inflammation

32
Q

How does Infliximab and Adalimumab work?

A

They bind directly to TNF-Alpha receptors

33
Q

How do corticosteroids work?

A

They induce the synthesis of IkBa, a protein that traps and inactivated NF-kB

34
Q

What does NF-kB do?

A

It is an activator of cytokine genes and mediator of the proinflammatory action of TNF and IL-1

35
Q

What are 2 antipruritic agents?

A

-Doxepin
-Pramoxine

36
Q

What do Trichogenic agents do?

A

They are hair producing agents

37
Q

What are 4 trichogenic and antitrichogenic agents

A

-Minoxidil
-Finasteride
-Bimatoprost
-Eflornithine

Pharmacology 3805 (5 decks)

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