Dermatolgy Flashcards
Deep infection if the hair follicles
Access, furuncle, boil
Fluid filled or puss filled <0.5cm
Bulls or blister
Flat change in skin with a color change (brown, blue, red, or hypo pigmented
Macular
Solid lesion >0.5-2.0cm
Greater than 2.0 is tumor
Nodule
Raised, solid lesion <=0.5cm, varies in color
Papuan
Raised solid lesion >0.5cm
Plaque
<=0.5cm elevated lesion that contains fluid
Vesicle
Transient rounded or flat top plaque
Wheal or hive
What skin pathogen/infection presents with purulent (pus) cellulitis
MRSA
When there is puss about, let it out!
Patient needs I&D
At what age does a patient get a shingles immunization?
60 yo. Patient must be immunocompetent
What serological test if positive makes lupus highly suspicious
Positive antinuclear antibodies
What diseases present with a palmar rash
Rocky Mountain spotted fever
Syphillis
Erythema multiforme
What skin condition is a precursor to skin cancer (SCC)
Actinic keratosis
How many days of antibiotics should be given for prophylaxis
3-5 days
How many days should antibiotics be given to treat infection
7-10 days
What is the gentlest vehicle of topical medication
Lotion
What is the most potent vehicle for topical medication
Ointment
What skin condition causes honey colored crusts and how is it treated?
Impetigo
Topical antibiotic Muripicin
What skin condition causes a herald patch
PR
Pityriasis rosea
What skin condition causes burrows
Scabies
Treated with scabacide prometharin
What skin condition causes a sandpaper textured rash?
Strep rash
Treated with penicillin
What skin condition causes a pearly domed module?
BCC refer
What skin condition causes a Christmas tree pattern rash
PR
What skin condition causes a bright beefy red rash
Candida rash
Topical anti fungal
What skin condition causes silvery scales
Psoriasis
Treated with topical & systemic agent
What skin condition causes a bulls eye lesion
Lyme disease
Doxycycline treated
What skin condition causes nits?
Head lice
Treated with scabacide
What skin condition causes a dermatomal rash?
Shingles
Treated with antiviral
What skin condition causes a butterfly malar rash
Lupus
Refer
What skin condition causes recurrent highly pruitic rash and/on flexor and extensor surfaces
Eczema
Treated with topical steroid
What skin condition causes HSV infection of the finger
Herpatic whitlow
Treasured with oral antiviral
With phytodermatitis or poison ivy, how do you treat it when >=20% of total body surface area is affected?
Systemic corticosteroid
Infection if the upper dermis of skin
Erysipelas
Strep infection
Requires antibiotics
TBSA % of head and neck
9%
TBSA % of upper limbs
9%
TBSA % of trunk
36%
TBSA % of palmar aspect of hand
1%
TBSA % of genitalia
1%
TBSA %of lower limbs
18% each
The classic rash looks like small red spots or petechiae and starts to abrupt on both of the hands and feet including the palms and soles. Rapidly progressing toward the trunk until it becomes generalized. The rashes appear on the third day after the abrupt onset of high fever accompanied by a severe headache, myalgia, conjunctival infection, nausea/vomiting, and Arthralgia. It can be fatal and the highest incidence is in South Eastern/South central areas of the country. Most cases occur during the spring and early summer season.
Rocky Mountain spotted fever
Precursor to skin cancer
Actinic keratosis
Risk factors for this condition include chronic sun exposure, fair skin, aging, occasionally progresses to squamous cell carcinoma, serves as a marker of chronic skin damage, so need to follow up with dermatology and self inspection monthly.
Actinic keratosis
Symptoms include sudden onset of sore throat, cough, fever, headache,stiff neck, photophobia, and changes in level of consciousness. The appearance could be toxic. In some cases, there is an abrupt onset of petechial to hemorrhagic rashes in the axilla, Flanks, wrists, and ankles. Rapid progression in fulfillment cases results in death within 48 hours. The risk is higher for college students residing in dormitories. It is spread by aerosol droplets. Rifampin prophylaxis is recommended for close contacts.
Meningococcemia
The classic lesion is an expanding red rash with central clearing that resembles a target. The bull’s-eye rash appears within 7 to 14 days after a deer tick bites. The rash feels hot to the touch and has a rough texture. Common locations are the beltline, axillary area, behind the knees, and in the groin area. It is accompanied by flu like symptoms. The lesion spontaneously resolved within a few weeks. It is most common in the north east region of the US. Use of DEET containing repellent on clothes in skin can Repel deer ticks
Erythema migrans or early Lyme disease
A reactivation of the varicella zoster i.e. chickenpox virus that has laid dormant in nerve cells. This involves the skin of a single dermatome or less commonly several dermatones
Herpes zoster or shingles
What is the pharmacological management for herpes zoster or shingles
NSAIDs or narcotic analgesics for pain. Antiviral agents if patient presents within 72 hours of symptoms. Antiviral agents to all immunocompromise patients.
What is a complication of herpes zoster or shingles
Post herpetic neuralgia; consider TCAs, gabapentin, pre-Gabalin, capsaicin cream
When is the herpes zoster vaccine given
All immunocompetent patients greater than or equal to 60 years old
A sight threatening condition caused by the activation of the herpes zoster virus that is located on the ophthalmic branch of the trigeminal nerve five. Patient reports sudden eruption of multiple vesicular lesions that are located on one side of the scalp, forehead, and the sides and tip of the nose. The eye lid on the same side is swollen and red. The patient complains of photophobia, eye pain, and blurred vision. This is more common in elderly patients . Refer to ophthalmologist or the ED as soon as possible
Shingles infection of the trigeminal nerve i.e. herpes zoster opthalmicus
How do you diagnose melanoma
ABCDE pneumonic
A assymetry
B border is irregular
C different colors within the same region
D diameter >6mm ( in whites primarily on lower legs and back; in blacks on hands, feet & Nails
E enlargement
Common in the 50 and 60 years old patients. Most common sites are head and neck. Usual appearance is pearly domed nodule with overlying tell telangiectatic vessels, later, central ulceration and crusting. Occurs 40 times more common than squamous cell. Particularly common in Caucasians and uncommon in dark skin populations. Most important risk factor is sun exposure. Definitive diagnosis always with biopsy or excision of specimen. Presentations: nodular, superficial, other presentations. 70% occur on face. Typically present on face as a pink or flesh colored papule.
BCC
Crusts and bleeds over and over again. Sore that does not heal.
BCC
This is the most common type of melanoma in African-Americans and Asians, and is a subtype of melanoma. These dark brown to black lesions are located on the nailbeds i.e. sub ungua, Palmar and plantar surfaces, and rarely the mucous membranes. Sub ungual melanomas look like longitudinal black to brown band is on the nail bed.
Acral lentiginous melanoma
Direct trauma to the nailbed resulting in pain and bleeding that is trapped between the nailbed and the finger/toenail. If the hematoma involves greater than 25% of the area of the nail, there is a high risk of permanent is Ischemic damage to the nail matrix if the blood is not drained. One method of training i.e. trephination a sub ungual hematoma is to straighten one end of a steel paper clip or to use An 18 gauge needle and heat it with a flame until it is very hot. The hot end is pushed down gently until a 3 to 4 mm hole is burned on the nail. The nail is pressed down gently until most or all of the blood is drained or suctioned with the smaller needle. Blood may continue draining for 24 to 36 hours.
Sub ungual hematoma
This condition creates target like lesions. It is an immune mediated reaction usually caused by infection such as herpes Symplex virus or mycoplasma pneumonia, sometimes meds. These medications include NSAIDs, sulfonamide, antibiotics, antiepileptics. These lesions may also occur in lupus. These lesions are usually on extremities, Self limited and results in 2 to 4 weeks, Common is a targetoid or Iris appearance. Also papules, macules, plaques, vesicles
Erythema Multiforme
Stevens-Johnson syndrome
What drug classes are associated with Stevens Johnson syndrome
Penicillin, sulfa’s, barbiturates, and phenytoin (Dilantin)
Patients with what disease have a 40 fold increased risk of Steven Johnson syndrome due to sulfa drugs
HIV infection
A deficiency in vitamin D in pregnancy results in
Infantile rickets i.e. brittle bones, skeletal abnormalities
Lesions in impetigo, 2nd° burn with blisters, and Steven Johnson syndrome are
Bulla
Hepatic lesions are
Vesicles
Acne lesions are
Pustules
Freckles and small cherry angiomas are what kind of lesions
Macules
Nevi and nine cystic acne what type of lesions
Papules
Psoriatic lesions are what kind of lesions
Plaques
Deep infection of the hair follicles
Abscess, furuncle , boil
Common benign neoplasm, 10 to dark brown, common in older adults
Seborrheic keratosis
Soft and round wart like flashy growth in the trunk that are located mostly on the back. Lesions on the same person can range in color from like tan to black. It is asymptomatic.
Seborrheic keratosis
Raise and yellow colored soft plaques that are located under the brow or upper and or lower lids of the eyes on the nasal side. It may be a sign of hyperlipidemia if present in person is younger than 40 years of age.
Xanthelasma
An increase in estrogen can cause what condition in women
Melasma
These lesions are due to a nest of malformed arterioles . It is asymptomatic.
Cherry angioma
When should you avoid prescribing topical steroids
Avoid steroids in case of suspected fungal ideology because it can worsen the infection. Also avoid in infants, children, and adults with thin facial skin. With topical steroids hypothalamus – pituitary – adrenal axis suppression may occur with excessive or prolonged use. It can cause straie, skin atrophy, telangiectasia. And acne and hypopigmentation
What is the pharmacological management for psoriasis
Emolients to hydrate skin i.e. Lubriderm, Aquaphor, Eucetin. Topical steroids at the lowest strength due to skin pigment changes. Methotrexate. Systemic agents prescribed by dermatology such as Humira
New psoriatic plaques forming over lesions and areas of skin trauma
Koebner phenomenon
Pinpoint areas of bleeding remain in the skin when a psoriasis plaque is removed
Auspitz sign
Does psoriasis cause pitted fingernails and toenails
Yes
Can psoriasis cause psoriatic arthritis
Yes
When prescribing a patient Hugmira, Enbrel, and Remicade, what labs should be gotten
Baseline PPD, CBC with differential. This is due to an associated higher risk of serious fatal infections, malignancy, TB, fungal infections, and sepsis
What is Goeckerman regimen for psoriasis
UVB light and tar derived topicals
What is a complication of psoriasis resulting from a beta hemolytic streptococci’s group infection usually due to strep throat
Guttate psoriasis
Pre-cancerous precursors to squamous cell carcinoma
Actinic keratosis
What cream can be prescribed for actinic keratosis
Fluorouracil cream 5% used over several weeks
What is the pharmacologic management for antifungal therapy
- azoles
- afine (allyamines)
Apply 1-2 inches beyond the rash
Treat 1-2 weeks
Then treat 1-2 weeks after resolution to prevent recurrence
When a patient has repeat fungal infection what must also be considered
Immunocompromised states such as HIV and diabetes with extensive infection, failure to respond to treatment.
Tinea capitis
Had
Tinea corporis
Body surfaces
Tinea cruris
Jock itch
Tinea pedis
Foot
Tinea unguium
Nail
What are the most common pathogens for fungal infections
Epidermophyton, trichophyton, microsporum
What treatment is the most effective for toenail fungus
Oral terbinafine (lamasil) Takes six months for fingernail and 12 months for toenail to grow out regardless of treatment
How do you get a sample of a fungal infected nail plate for diagnosis
Trim away distal nail plate to expose affected nail. Use a small curette to obtain Nail fragments. Place on slide and drop of KOH. Microscopic visualization
This is a fungal nail infection and terbinafine 73 to 79% cure rate if treated for 6 to 12 weeks. Others are less effective. Watch for hepatotoxicity and drug interactions i.e. statins. Topical or poorly effective.
Onychomycosis
A superficial infection caused by yeasts Pityrosporum orbiculare and pityrosporum ovale.
Tinea versicolor
Patient complains of multiple hypopigmented round macules on the chest, shoulders, and or back that appear after skin becomes tan from sun exposure. Asymptomatic.
Tinea versicolor
If the KOH slide shows hyphae and spores what condition would this be
Tinea versicolor
This condition is diagnosed due to clinical symptoms with pruritus being the predominant symptom. Clues are chronic and the recurring. Family history of allergic disease.
Atopic dermatitis or eczema
What is the first line treatment for a topic dermatitis or eczema
Topical steroids or first line. Mild will get hydrocortisone 1% to 2.5%. Medium will get Triamcinolone
Medium to high potency steroid use for 10 days and then taper off to weaker steroids and then stop. Systemic oral antihistamines for itching i.e. Benadryl or hydroxyzine. Skin lubricants such as Eucerin. Avoid drying skin/xerosis since it will exacerbate eczema. No hot bath, harsh soaps, chemicals, wool clothing. Hydrating baths avoid hot water and follow immediately with skin lubricants.
This skin condition is due to direct exposure to a substance. Trigger induces an immune response via T cell mediated response. Maybe allergic or irritant induced. Example would be poison ivy.
Contact dermatitis
Do you treat contact dermatitis with a topical steroid
No
Should a topical steroid be used on broken skin
No
How do you treat contact dermatitis
Stop exposure to substance. Calamine lotion, topical steroids, oatmeal bath i.e. Aveeno. If severe rash, oral prednisone for 12 to 14 days and then wean. Avoid reexposure.
And Obese adult complains of bright red and shiny lesions that itch or burn, located on the intertriginous areas i.e. under the breast in females, axillae, abdomen, groin, the web spaces between the toes. The rash may have satellite lesions which are small red rashes around the main rash.
Superficial candidiasis
Patient complains of a severe sore throat with white adherent plaques with a red base that are hard to dislodge on the pharynx. In healthy adults, this condition may signal an immunodeficient condition.
Oral thrush
How do you treat the intertriginous areas of a patient with superficial candidiasis
Nystatin powder and or cream. BID. Over-the-counter topical antifungal’s can also be used. Keep skin dry and aerated