Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Dermatology > Dermatitis > Flashcards

Dermatitis Flashcards

You may prefer our related Brainscape-certified flashcards:
Dermatology Board Prep flashcards
1
Q

Hyperkeratosis

A

Increased thickness of keratin layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Parakeratosis

A

Persistence of nuclei in the keratin layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Acanthosis

A

Increased thickness of epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Papillomatosis

A

Irregular epithelial thickening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Spongiosis

A

Oedema between keratinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dermatitis

A

Skin lesions with similar clinical & pathological features but different PATHOGENETIC MECHANISMS (i.e. different causes)

Spectrum of disease.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Acute phase dermatitis

A

> Papulovesicular
Red (erythematous) lesions
Oedema (spongiosis)
Ooze or scaling and crusting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Chronic phase dermatitis

A

Thickening (lichenification)
Elevated plaques
Increased scaling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

General features of Dermatitis

A

Itchy
Ill defined
Erythematous
Scaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

In drug reaction-related Dermatitis, what type of cells are present?

A

Eosinophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Contact Allergic Dermatitis

A

One of the most common types of dermatitis

Very common.

  • in response to chemicals, topical, therapies, nickel, plants
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Gloved hands - why are the back of the hands normally more affected in contact dermatitis?

A

Skin on the back of the hand is thinner so allergen can penetrate skin faster

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Immunopathology of contact allergic dermatitis

A

> Langerhans cell in epidermis processes antigen

> Processed antigen is then presented to Th cells in dermis

> Sensitised Th cells migrate into lymphatics and then to regional nodes where antigen is amplified

> Specifically sensitised T cells proliferate and migrate to and infiltrate the skin
—> DERMATITIS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Diagnosing contact allergy

A

Patch testing.

  1. Batteries of allergens are placed in small wells
  2. Applied to back skin and left in place for 48 hours
  3. Reactions checked after 96 hours
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

IRRITANT contact dermatitis

A

> Another v common type.

> non specific physical irritation rather than a specific allergic reaction

soap, detergent, cleaning products, water, oil

> Can be difficult to distinguish from allergic contact dermatitis and may CO EXIST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Nappy rash

A

Irritatn contact dermatitis to urine

17
Q

Atopic eczema/dermatitis

A

Itch scratch cycle.

Ill defined erythema and scaling

Generalised dry skin

Flexural distribution

Associated w/asthma, allergic rhinitis, food allergy

At flexures

Some fissuring

18
Q

What is pathognomonic of atopic eczema?

A

Scaling/dry skin at the ears.
Behind the ears/ at “flexure”.

Very characteristic

Does your child cry when you pull his top off? (Hitting his ears)

19
Q

Atopic eczema chronic changes

A

> Lichenification
Excoriation (erosion caused by scratching)
Secondary infection

20
Q

What does crusting indicate in atopic eczema?

A

Staph aureus infection.

21
Q

Eczema herpeticum

A

Herpes simplex virus

MONOMORPHIC PUNCHED OUT LESIONS

Child is systemically unwell.

IV antivirals
Fluid resus.

22
Q

Atopic eczema - diagnostic criteria

A

Itching +

visible flexural rash
hx of flexural rash
personal history of atopy
Generally dry skin
Onset before age 2 years
23
Q

In infants, what other sites can be affected by atopic eczema?

A

Cheeks and extensor surfaces

24
Q

Eczema - treatment

A

1) Emollients
2) Avoid irritants including shower gels and soaps
3) Topical steroids
4) Treat infection
5) Phototherapy (UVB)
6) Systemic immunosuppressants
7) Biologic agents

25
Q

Most important gene in atopic eczema?

A

Filaggrin

26
Q

Discoid Eczema

A

Very well defined lesions

Disc shaped.

Scratchingis inducing

27
Q

Photosensitive eczema

A

Chronic actinic dermatitis

(cut off at collar is normally a big clue)

Often atopic patients

28
Q

Other cause of photosensitive eczema?

A

Secondary to photosensitising drugs

29
Q

Stasis eczema

A

Secondary to:

Hydrostatic pressure
Oedema
Red cell extravasation

30
Q

Seborrhoeic dermatitis

A

Cradle cap in babies

Nasolabial folds in adults/ adolescents

31
Q

Pompholyx eczema

A

Spongiotic vesicles

Vesicles are intensely itchy

32
Q

Lichen simplex

A

Scratching

A pruritic eczematous condition resulting from continued rubbing and scratching at a localised area of the skin

assoiciated with a period of anxiety.

Signs
- solitary unilateral plaque
- fresh coloured pink, hyper pigmented 
lichenified surface 
well defined shape

Dermatology (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions