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Derma all quiz Flashcards

1
Q

what do the patient need to avoid while beeing treated for C. trachomatis with doxycyclin?

A

Sunlight due to increased photo sensitivity

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2
Q

name a non STI cause of urethritis?

A

Reiters syndrom

arthritis, urethritis, conjuctivitis

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3
Q

NGU treatment

A

azithromycin
doxycycling
per os x7 days

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4
Q

GU treatment

A

ceftriaxon IM once

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5
Q

trachoma vaginalis treatment

A

metronidazole

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6
Q

medical name of vaginal discharge?

A

physiologic leukorrhea

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7
Q

normal vaginal pH?

A

3.8-4,7

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8
Q

pathology when vaginal pH above 4,7?

A

Bacterial vaginosis

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9
Q

pathology when vaginal pH above 5.2

A

Trichomonasis

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10
Q

Tx vaginal bacteriosis

A

topical clindamycin

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11
Q

Tx vulvovaginal candidosis

A

topical azoles

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12
Q

why must vaginal swap not be taken from cervix in diagnosis?

A

bec. above 4.7 pH is pathologic i vagina but up to 5.0 is physiologic in cervix

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13
Q

cells seen in bacterial vaginosis?

A

Clue cells (epithelial cells covered in bacteria)

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14
Q

ten functions of skin

A

name them

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15
Q

size of skin

A

2m2

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16
Q

urticaria

A

IgE mediated pruritic edema in dermis

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17
Q

treatment of chronic urticaria

A
  1. parental antihistamin and locar antihistamin (last not preffered)
  2. paretal GC
  3. epinephrin IM 0.3-0.5mg IM
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18
Q

name a strong drug against urticaria

A

doxepin/hydroxyzine

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19
Q

why oral antihistamil in urticaria?

A

spreads so dont treat locally

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20
Q

what is eczema?

A

A form of dermatitis - inflammation of epidermis

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21
Q

eczema vs psoriasis?

A

eczema on flexor

psoriasis on extensor

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22
Q

exogenous eczemas? (4)

A

irritative contact dermatitis
allergic contact dermatitis
photosensitiv eczema
Lichen simplex

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23
Q

symptomes of chronic allergic contact dermatitis

A

lichinification

fissures

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24
Q

lichen simplex

A

eczema due to scratching (no underlying dermatitis)

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25
endogenous eczemas? (6)
``` atopic dermatitis seborrhaic dermatitis dyshidrosis eczema microbicum /nummural stasis dermatitis asteatotic dermatitis ```
26
dyshidrosis
dermatitis of hands due to constant washing, tinea, nikkel
27
what is seen in atopic dermatitis as etiology?
Genetic Increasec IgE Filaggrin mutation
28
Name two spescial named signs in atopic dermatitis
Hertogen sign (loss of lateral eyebrow ) Denni-Morgan sign (infraorbital folds) Dermatographism (white when stroking)
29
two criteria types in atopic dermatitis
1. Hanifin and Rajka criteria (SCORAD)
30
atopic dermatitis treatment
mild: topical steroids and calcineurin inhibitors severe: cyclosporin, dupilumab, antihistamin
31
how long can you use cyclosporins?
not more then one year
32
drug eruption vs adverse cutaneous drug reaction
Drug induced skin reaction resolving on its own vs. fatal skin reaction
33
types of drug eruptions?
TEN erythroderma Anti-convulsant HS syndrom
34
erythroderma
almost whole skin is red, tighness and pruritis + non spesific
35
TEN clinical
dubepidermal blisters, pruritis, burning, MOF, sepsis + non spesific
36
anti-convulsant hypersensitivity syndrom
rash, fever, LAD, MOF
37
anti-convulsant hypersensitivity syndrom
rash, fever, LAD, MOF
38
cutaneous drug reaction urticaria
NSAID, aspirin, penicillin
39
cutaneous drug reaction anaphylaxis
AB, contrast medium
40
cutaneous drug reaction acneiform
GC, anabolic steroids, contraceptivs
41
cutaneous drug reaction TEN
NSAID, penicillin, carbamazapen
42
cutaneous drug reaction erythroderma
allopurisol
43
cutaneous drug reaction anti-convulsant HS syndrom
carbamazapen (anticonvulsant drug)
44
impetigo types my staff/strep
staff: bullous strep: non-bullous
45
treatment of impetigo, folliculitis, furuncle, carbulcle
mupiricin or fusidin locally | penicillin, cephlosporin or doxycycling systemic
46
erysipelas definition and cause
superficial skin infection in upper dermis. By str. pyogenis
47
treatment of erysiphelas
must be systemic: aminopenicillin, clindamycin
48
erysipelas skin sign
red, hot, swollen unilateral
49
subtypes of erysiplelas
hemorrhagic gangrenosum vesicolor erythromatous
50
erysipelas vs cellulitis
cellulitis is deeper into subcuris, not raised leasion and diffuse borders. may have bullae and superficial necrosis
51
complications of erysipleas
necrotizing faciitis | lymphangitis
52
exogenous cutaneous tuberculosis
tuberculosis verrucosa | primary Tb inoculation
53
endogenous cutaneous tuberculosis
1. lupus vulgaris 2. scrofuderma 3. tuberculid 4. Miliary Tb
54
antibiotic in Tb RIPES
``` rifamficin isoniazid pyrazinamid ethanbutol streptomycin ```
55
stages in lymes disease
1. localized lymes disease 2. early disseminated 3. late disseminated
56
treatment of lymes disease
1. doxycyclin 100mg/x2 day 2w 2. amoxicillin 500mh x3 day 2w 3. ceftriaxon 2g/day in CNS involvment
57
pompholyx
dyshidrotic eczema
58
pompholyx treatment
prednisolon 70mg/day 1-2w wet dressing topical CS
59
what causes onchomycosis?
trichopyton rubrun - tinea unguium
60
how does the trichophyton eat in onychomycosis?
eat keratin of the nail
61
diagnosing onchoycosis?
KOH preparation of nailclipping | or PAS stain
62
treatment of onychomycosis?
litraconazole 100mg/day | terbinafin 250mg/day
63
what is tinea?
disease caused by dermatophytes
64
dermatophytes (3)
trichophyton epidermophyton microsporum
65
name of fungi infection on skin, hair, nail
skin: epidermatomycosis hair: trichomyosis nail: onychomycosis
66
what is microsporia?
superficial mycoses - malassezia - candida - dermatophytes
67
cause of pityriasis vesicolor?
malassezia furfur fungi (yest)
68
how does malassezia cause color change?
degrade lipids releasing acids that damages melanocyte.
69
where is the malassezia fungi in out skin?
corneum layer (superficial)
70
pityriasis vesicolor treatment
1. selenium sulphide 2. terbinafine 3. ketoconazole
71
Leishmania
flesh eating protozoa
72
types of leishmania?
braziliensis - mucocutaneous tropica - cutaneous donovani -visceral
73
treatment for leishmaniosis
stebogluconate (T bone) | amphotericin B
74
tuberculoid leprosy clinical and treatment
large hypopigmented/erythematous plaques. Loss of hair, sweatglands and nerves at site so painless. Dapson 5 yrs
75
lepromatous leprosy clinical and treatment
neuropathy, raised plaques on extensor, facial disformaty (thick nodular skin) lions face Treatment Rifamficin 3 yrs, Dapson forever
76
most common leprosy?
undetermined leprosy | erythematous/hypopigmented scaling leasions
77
HPV warts?
``` verruca vulgaris (common) verruca plantaris (foot) verruva plana (flat) (face hands) condyloma acc (genital) ```
78
define a wart
firm hyperkeratotic papule in corneum with vegitations
79
HPV 1-4
verruca vulgaris
80
HPV 6, 11
pharyngeal papilomatosis | comdyloma accumulata
81
HPV 16, 18, 31, 33
adenocarcinoma | squamous cell carsinoma
82
HPV vaccine
Gardicil
83
HPV viru attacks
E6 - p53 | E7 - RB
84
collagen in skin
1 (most) 3 17 (hemidesmosomes
85
drugs that can cause TEN
aminopenicillin rifamficin trimetroprime
86
what causes the necrosis in TEN
t-cell release of GRANULYSIN
87
what is erythroderma?
exfoliate dermatitis covering almost whole skin
88
antibodies in Lupus
ANA anti-SSA/anti-SSB (SCLE / neonatal) anti dsDNA (SLE) c1q antibodies (urticaria, vasculitis, nephritis)
89
biologic treatmend lupus?
belimumab
90
treatment of lupus BAM BAM BAM
``` topical CC oral CC IV CC antimalarian drugs bilogi: belimumab methtrexat ```
91
enzymes in dermatomyositis
CPK GOT LDH GPT
92
poykiloderma
pepper and salt skin (hype and hyperpogmented spots
93
dermatomyositis treatment
CS: prednisolon methotrexat azithroprin IVIG
94
skinsymptomes in dermatomyositis
symmetrical eryth. rash - helitrope rash - malar rash (+nasal fold) - V sign on chest - Holster sign tighs
95
keratoachantoma | trichoepitilioma
1. tumor around glands of hairfollicles | 2. benings tumor of hairfollicle
96
chemo in BCC
imiquimod
97
cells of squamous cell carcinoma origin
st. spinosum sq cells
98
lentigo
a small, sharply circumscribed, pigmented macule surrounded by normal-appearing skin.
99
morphology of bowen syndrom
erythematous, scaly irregular
100
mycosis fungiosis morphology?
well-demarcated skin plaques which eventually grow to form mushroom like tumors (hence name)
101
two key words in psoriasis
parakeratosis | acanthosis
102
types of psoriasis
``` plaque erythroderma guttat palmosolar inverse ```
103
lichen planus morphology
``` Purple Poligonal Pruritic Papuler wickham stria ```
104
lichen planus etiology
idiopathis cytotoxic t-cell activation due to keratocyte MHI I ag presentation --> achantosis due to killing of keratocytes
105
treatment against Lichen planus
topical steroid: Bethametason
106
pityriasis rosea
self limiting erythema by HH7
107
treatment in acne
mild: benoyl peroxide, retinoid severe: isotretionine
108
types of acne
hidradenitid (hairfollicle) neonatal acne vulgaris (inf/non-inf)

Dermatology (1 decks)

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