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HPIM 19th Derma > Derma > Flashcards

Derma Flashcards

1
Q

Pathognomonic sign of Scleroderma

SLE, DerMatomyositis

A

Periungual Telangiectasia

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2
Q

Most common of all drug reactions

A

Morbilliform

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3
Q

Second most frequent type of cutaneous reaction to drugs

A

Urticaria

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4
Q

Associated with red man syndrome

A

Vancomycin

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5
Q

Blisters developing on target lesions with mucosal involvement with TBSA detachment <10%

A

SJS

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6
Q

TBSA >30% mucosal/epidermal detachment

A

TEN

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7
Q

Detachment of the DISTAL part of the nail plate

A

Onycholysis

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8
Q

Detachment of the PROXIMAL part of the nail plate

A

Onychomadesis

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9
Q

Mucosal involvement and target lesions associated with HSV

A

Erythema multiforme

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10
Q

Poor prognosis in SJS/TEN

A

Intestinal and pulmonary involvement

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11
Q

Cytologic technique most often used in the diagnosis of HSV or VZV

A

Tzanck smear
(presence of multinucleated epithelial giant cells)

Lesion examined: early vesicle

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12
Q

“Apple Jelly” on diascopy

A

Granulomas

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13
Q

Ash leaf spots on Wood’s light

A

Tuberous Sclerosis

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14
Q

Clinical Features if Atopic Dermatitis

A
  1. Pruritus and scratching
  2. Exacerbations and remissions
  3. Typical lesions of eczematous derm
  4. Personal or Fam Hx of Atopy
  5. > 6 weeks
  6. Lichenification
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15
Q

Prominent characteristic of AD in all age groups

A

Pruritus

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16
Q

Common histologic finding of eczema

A

Spongiosis

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17
Q

Mutation gene associated in AS

A

Filaggrin

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18
Q

MC type of ICD

A

Chronic low-grade irritant dermatitis

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19
Q

MC area of involvement of ICD

A

Hand

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20
Q

MC cause of ACD

A

Exposure to plants (Urushiol)

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21
Q

Immune-mediated disease characterized by erythematous, sharply demarcated papules and rounded plaques covered by silvery micaceous scale

A

Psoriasis

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22
Q

Traumatized areas develop lesions of psoriasis

A

Koebner phenomenon

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23
Q

MC variety of psoriasis

A

Plaque-type

stable, slowly enlarging plaques, which remain unchanged for long periods of time

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24
Q

Psoriasis common in children and young adults

A

Guttate/eruptive psoriasis

frequently after an URTI with GBHS

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25
Pruritic, polygonal, flat-topped, violaceous papules
Lichen planus
26
Network of gray lines on the surface of lichen planus
Wickham’s striae
27
Associated with LP
Hepatitis C infection
28
Clinical hallmark if acne vulgaris
Comedone
29
MC location for acne
Face
30
Bacteria responsible for acne vulgaris
Proprionobacterium acnes
31
Characterized by erythema, telangiectases, superficial pustules
Acne rosacea
32
Characterized by discrete lesions, most often found on the face, scalp and/or external ears
Discoid Lupus Erythematosus
33
Lesion specific for DLE
“Carpet tacking”
34
MC location of stasis dermatitis
Lower extremities, usually medial aspect of the ankle
35
Represents a large proportion of cases of occupation-associated skin disease
Hand eczema
36
Transient lesions that are composed of a central wheal surrounded by an erythematous halo or flare
Urticaria
37
Linear wheals following minor pressure or scratching of the skin
Dermatographism
38
Subcutaneous edema
Angioedema
39
Sensation that elicits the desire to scratch
Pruritus
40
Systemic conditions associated with pruritus
``` CKD cholestasis pregnancy CA Thyroid disease PV delusions of parasitosis ```
41
Performed on scaling lesion where fungal etio is possible
KOH (10-20%) | KOH dissolves KERATIN, brief heating accelerates keratin dissolution
42
Identified by KOH
hyphae:dermatophyte pseudohyphae and budding yeast:Candida fragmented hyphae and spores:tinea versicolor
43
MCC of Drug-induced Hypersensitivity Syndrome (DIHS)
Allopurinol
44
Outer layer of epidermis separates readily from basal layer with lateral pressure
TEN | necrotic epidermis
45
Cutaneous reactions in DIHS
Begins 2-8 weeks after the drug is started and lasts longer than mild eruptions after drug cessation
46
Complications of DIHS
late-onset autoimmune thyroiditis
47
Not associated with Eosinophilia in DIHS
Lamotrigine Abacavir Dapsone
48
Second most frequent type of cutaneous reaction to drugs
Urticaria
49
Most frequent causes of urticaria
``` ACEI Aspirin NSAIDS Penicillins blood products ```
50
Three mechanisms of Urticaria/Angioedema/Anaphylaxis
IgE dependent mechanism Circulating immunce complexes Non-immunologic activation
51
Group of autoantibody-mediated intraepidermal blistering diseases characterized by loss of cohesion between the epidermal cells (acantholysis)
Pemphigus
52
Manual pressure to skin elicits separation of the epidermis
Nikolsky sign
53
MC cutaneous manifestation in dermatomyositis
Heliotrope rash | purple-red discoloration of the upper eyelids sometimes assoc with scaling or periorbital edema
54
Pathognomonic of dermatomyositis, flat-topped papules over the dorsal interphalangeal joints
Gottron’s papules
55
Thin violaceous papules and plaques on the elbows and knees of dermatomyositis
Gottron’s sign
56
Distinguishes dermatomyositis from SLE and SS
Poikiloderma
57
Autoantibodies present in Subacute cutaneous lupus erythematosus (SCLE)
anti-Ro
58
Treatment for SCLE
Aminoquinoline antimalarials
59
Seen when there is an extravasationnof RBCs into the dermis, lesions DO NOT blanch with pressure
Purpura
60
Dermal edema
Urticaria
61
Urticaria precipitated by heat, excercise or emotion
Cholinergic urticaria
62
Honey-colored crusts
Bullous impetigo
63
Scarlatiniform exanthem
Scarlet fever

HPIM 19th Derma (1 decks)

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