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RRCCPA PATHO SCHOENWALD DERM > DERM SCHOENWALD EXAM 3 > Flashcards

DERM SCHOENWALD EXAM 3 Flashcards

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Dermatology Board Prep flashcards
1
Q

________ is macules and papules with loss of pigment

A

Vitiligo

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2
Q

Hashimotos, DMI and Addison disease are linked to _______

A

vitiligo

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3
Q

Areas vitiligo affects

A

Hands/wrists, perioral, anogential

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4
Q

________ are hyperpigmented lesions that darken with sunlight

A

freckles

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5
Q

________ are hyperpigemented lesions that do NOT darken with sunlight

A

lentigo

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6
Q

Acute inflammatory range from ____ to _____

A

days to weeks

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7
Q

neutrophils, edema, epidermal, vascula and subcutatnous injury are common in ______________

A

acute inflammation

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8
Q

Urticaria is a type _____ immune reaction.

A

I

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9
Q

Urticaria has hives and is itchy (______med term)

A

pruritic

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10
Q

Urticaria skin findings

A

prupritic nodule, edemaous swelling (wheals) and plaques, formation of bullae

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11
Q

Perivascular edema is a microscopic finidng of ________

A

urticaria

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12
Q

Urticaria is commonly caused by _______ (4)

A

drugs, household exposures (soaps), insect bites and foods

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13
Q

______is charaterized by erythema, edema and vesicle formation which can progress to oozing and crusting

A

Acute eczematous dermatitis

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14
Q

in chronic Acute eczematous dermatitis you may find (skin description)

A

raised plaques

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15
Q

Micro: Eosinophilia and epidermal spongiosis is found in

A

Acute eczematous dermatitis

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16
Q

Describe microscopic findings of Acute eczematous dermatitis

A

eosinophillia and epidermal spongisosis

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17
Q

Pathology of Acute eczematous dermatitis is the antigen is taken up by ________ cells and presented to the T cell. Upon exposure T cells release ________

A

Langerhans, cytokines

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18
Q

Allergic contact dermatitis, atopic dermatitis, irritant related dermatisis are examples of_______

A

Acute eczematous dermatitis

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19
Q

____________ is a hypersensitivty reaction to infections and drugs

A

Erythema multiforme

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20
Q

90% of infection induced Erythema multiforme is caused by ___

A

HSV

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21
Q

Drugs that cause Erythema multiforme

A

sulfaonmides, penicillin, slaicilyates

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22
Q

Macules, papules, vesicles and bullae are charateristic of_______

A

Erythema multiforme

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23
Q

________ is a variant of Erythema multiforme where the patient is febrile and involves the lips and oral mucous

A

Stevens Johnson

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24
Q

We are worried about secondary infection that could lead to sepsis in ____________

A

Stevens Johnsons

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25
Q

Less than 10% of epidermal detachment

A

Erythema multiforme Stevens Johnsons syndrome

26
Q

_____________ is a variant of Erythema multiforme where there is diffuse sloughing and nevrosis of cutaneous and mucosal epthelium

A

Toxic epidermal necrolysis

27
Q

Toxic epidermal necrolysis microscopy: diffuse ________ necrosis leading to blister formation. perivasuclar _______ and dermal edema

A

epidural, lymphocytes

28
Q

________ epidermal detachment in toxic epidermal necrolysis

A

greater than 30%

29
Q

The two variants of Erythema multiforme

A

Stevens Johnsons and TED (toxic epidural necrolysis)

30
Q

Steven johnson syndrome is a type _______ hypersensitivity

A

IV

31
Q

Toxic epideral necrolysis is more common in adults or kids

A

adults

32
Q

Chronic inflammatory skin conditions can last for _________ to _______

A

months to years

33
Q

Chronic inflammation leads to _______ of the skin

A

thickening

34
Q

Psoriasis involves what skin layers? what happens on the top one?

A

epidermis and dermis with epidermal hyperplasia and hyperkartosis

35
Q

Auspitz sign

A

removal of scales causes petechial bleeding

36
Q

Skin finding in Psoriasis

A

Red plaques covered in silvery white scales

37
Q

Psoriasis commonly affects:

A

extensor surfaces (elvboes, knee) and scalp and lumbosacral surface)

38
Q

Psoriasis microscopy: elongated ________ __________ with thinning of overlying __________

A

dermal papillae, epidermis

39
Q

You may find (nail finding) in Psoriasis

A

pitting

40
Q

Psoriatic arthritis is related to ________ ____________ with a positive HLA _______

A

ankylosing spondylysis, B27

41
Q

Dermatitis herpetiformis is a pruritic vesicular dermatosis related to ___________

A

celiac (gluten inseneisitivity)

42
Q

___________ is charaterized by burning and itching lesions on extensor surfaces (knees, elbows, back and buttocks)

A

Dermatitis herpetiformis

43
Q

Dermatitis herpetiformis microscopy: ___________ formation with dense ___________ infiltration and micro_________formation

A

cleft, neutrophilic, abecess

44
Q

What Ab is found in the serum in patients with Dermatitis herpetiformis

A

antiendomysial IgA (remeber IgA are GI related…Dermatitis herpetiformis is related to celiac)

45
Q

___________ is a moist or greasy macule or papule on an erythemtous base which scales and crusts

A

Seborrheic dermatitis

46
Q

Dandruff and cradle cap are forms of

A

seborrheic dermatitis

47
Q

Tan to dark brown papule with a “stuck on appearance”

A

Seborrheic keratosis (dont confuse with seborrheic dermatitis)

48
Q

Seborrheic keratosis can be flat or raised is ___________ demarcated with a pink to brownish black pigmentation. Common in older folks

A

sharply

49
Q

Seborrheic keratosis microscopy: sheets of ______-like cells, hyper_______ and _______filled cysts

A

basal, keratosis, keratin

50
Q

Rough and sand paper like and can have a horn

A

Actinic keratosis

51
Q

actinic keratosis microscopy: _________ of keratinocytes in the _______ portion of the epidermis

A

dysplasia, basal

52
Q

Actinic keratosis is a begnign/precancerous (choose 1) and is caused by ________

A

precancerous, UV exposure

53
Q

Bullae involve the ____ and ______

A

oral mucous and skin

54
Q

General microscopy for bullae: _____________ which leads to bullae formation

A

acntholysis

55
Q

Name the 4 phemigus

A

vulgaris (most common, 80% of cases), vegetans, foliaceous, ertythematosis

56
Q

a morbilliform rash is a __________ like rash with macules, papules and scattered about the body

A

measles

57
Q

Morbilliform rashes can be from drug reactions (particularly _________) usually start a the ______ and spread

A

penicillin, trunk

58
Q

Exanthem is on the ______

A

surface of the body

59
Q

Enanthems are found _________

A

in an orifice like the mouth

60
Q

Exantham and enathem are both usually caused by ______. What is a disease that exemplifies bouth

A

viruses, Hand Foot and mouth

61
Q

Phemphigus vulgaris

A

RRCCPA PATHO SCHOENWALD DERM (1 decks)

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