DERM SCHOENWALD EXAM 3

Question 1

________ is macules and papules with loss of pigment

Answer 1

Vitiligo

Question 2

Hashimotos, DMI and Addison disease are linked to _______

Answer 2

vitiligo

Question 3

Areas vitiligo affects

Answer 3

Hands/wrists, perioral, anogential

Question 4

________ are hyperpigmented lesions that darken with sunlight

Answer 4

freckles

Question 5

________ are hyperpigemented lesions that do NOT darken with sunlight

Answer 5

lentigo

Question 6

Acute inflammatory range from ____ to _____

Answer 6

days to weeks

Question 7

neutrophils, edema, epidermal, vascula and subcutatnous injury are common in ______________

Answer 7

acute inflammation

Question 8

Urticaria is a type _____ immune reaction.

Answer 8

I

Question 9

Urticaria has hives and is itchy (______med term)

Answer 9

pruritic

Question 10

Urticaria skin findings

Answer 10

prupritic nodule, edemaous swelling (wheals) and plaques, formation of bullae

Question 11

Perivascular edema is a microscopic finidng of ________

Answer 11

urticaria

Question 12

Urticaria is commonly caused by _______ (4)

Answer 12

drugs, household exposures (soaps), insect bites and foods

Question 13

______is charaterized by erythema, edema and vesicle formation which can progress to oozing and crusting

Answer 13

Acute eczematous dermatitis

Question 14

in chronic Acute eczematous dermatitis you may find (skin description)

Answer 14

raised plaques

Question 15

Micro: Eosinophilia and epidermal spongiosis is found in

Answer 15

Acute eczematous dermatitis

Question 16

Describe microscopic findings of Acute eczematous dermatitis

Answer 16

eosinophillia and epidermal spongisosis

Question 17

Pathology of Acute eczematous dermatitis is the antigen is taken up by ________ cells and presented to the T cell. Upon exposure T cells release ________

Answer 17

Langerhans, cytokines

Question 18

Allergic contact dermatitis, atopic dermatitis, irritant related dermatisis are examples of_______

Answer 18

Acute eczematous dermatitis

Question 19

____________ is a hypersensitivty reaction to infections and drugs

Answer 19

Erythema multiforme

Question 20

90% of infection induced Erythema multiforme is caused by ___

Answer 20

HSV

Question 21

Drugs that cause Erythema multiforme

Answer 21

sulfaonmides, penicillin, slaicilyates

Question 22

Macules, papules, vesicles and bullae are charateristic of_______

Answer 22

Erythema multiforme

Question 23

________ is a variant of Erythema multiforme where the patient is febrile and involves the lips and oral mucous

Answer 23

Stevens Johnson

Question 24

We are worried about secondary infection that could lead to sepsis in ____________

Answer 24

Stevens Johnsons

Question 25

Less than 10% of epidermal detachment

Answer 25

Erythema multiforme Stevens Johnsons syndrome

Question 26

_____________ is a variant of Erythema multiforme where there is diffuse sloughing and nevrosis of cutaneous and mucosal epthelium

Answer 26

Toxic epidermal necrolysis

Question 27

Toxic epidermal necrolysis microscopy: diffuse ________ necrosis leading to blister formation. perivasuclar _______ and dermal edema

Answer 27

epidural, lymphocytes

Question 28

________ epidermal detachment in toxic epidermal necrolysis

Answer 28

greater than 30%

Question 29

The two variants of Erythema multiforme

Answer 29

Stevens Johnsons and TED (toxic epidural necrolysis)

Question 30

Steven johnson syndrome is a type _______ hypersensitivity

Answer 30

IV

Question 31

Toxic epideral necrolysis is more common in adults or kids

Answer 31

adults

Question 32

Chronic inflammatory skin conditions can last for _________ to _______

Answer 32

months to years

Question 33

Chronic inflammation leads to _______ of the skin

Answer 33

thickening

Question 34

Psoriasis involves what skin layers? what happens on the top one?

Answer 34

epidermis and dermis with epidermal hyperplasia and hyperkartosis

Question 35

Auspitz sign

Answer 35

removal of scales causes petechial bleeding

Question 36

Skin finding in Psoriasis

Answer 36

Red plaques covered in silvery white scales

Question 37

Psoriasis commonly affects:

Answer 37

extensor surfaces (elvboes, knee) and scalp and lumbosacral surface)

Question 38

Psoriasis microscopy: elongated ________ __________ with thinning of overlying __________

Answer 38

dermal papillae, epidermis

Question 39

You may find (nail finding) in Psoriasis

Answer 39

pitting

Question 40

Psoriatic arthritis is related to ________ ____________ with a positive HLA _______

Answer 40

ankylosing spondylysis, B27

Question 41

Dermatitis herpetiformis is a pruritic vesicular dermatosis related to ___________

Answer 41

celiac (gluten inseneisitivity)

Question 42

___________ is charaterized by burning and itching lesions on extensor surfaces (knees, elbows, back and buttocks)

Answer 42

Dermatitis herpetiformis

Question 43

Dermatitis herpetiformis microscopy: ___________ formation with dense ___________ infiltration and micro_________formation

Answer 43

cleft, neutrophilic, abecess

Question 44

What Ab is found in the serum in patients with Dermatitis herpetiformis

Answer 44

antiendomysial IgA (remeber IgA are GI related...Dermatitis herpetiformis is related to celiac)

Question 45

___________ is a moist or greasy macule or papule on an erythemtous base which scales and crusts

Answer 45

Seborrheic dermatitis

Question 46

Dandruff and cradle cap are forms of

Answer 46

seborrheic dermatitis

Question 47

Tan to dark brown papule with a "stuck on appearance"

Answer 47

Seborrheic keratosis (dont confuse with seborrheic dermatitis)

Question 48

Seborrheic keratosis can be flat or raised is ___________ demarcated with a pink to brownish black pigmentation. Common in older folks

Answer 48

sharply

Question 49

Seborrheic keratosis microscopy: sheets of ______-like cells, hyper_______ and _______filled cysts

Answer 49

basal, keratosis, keratin

Question 50

Rough and sand paper like and can have a horn

Answer 50

Actinic keratosis

Question 51

actinic keratosis microscopy: _________ of keratinocytes in the _______ portion of the epidermis

Answer 51

dysplasia, basal

Question 52

Actinic keratosis is a begnign/precancerous (choose 1) and is caused by ________

Answer 52

precancerous, UV exposure

Question 53

Bullae involve the ____ and ______

Answer 53

oral mucous and skin

Question 54

General microscopy for bullae: _____________ which leads to bullae formation

Answer 54

acntholysis

Question 55

Name the 4 phemigus

Answer 55

vulgaris (most common, 80% of cases), vegetans, foliaceous, ertythematosis

Question 56

a morbilliform rash is a __________ like rash with macules, papules and scattered about the body

Answer 56

measles

Question 57

Morbilliform rashes can be from drug reactions (particularly _________) usually start a the ______ and spread

Answer 57

penicillin, trunk

Question 58

Exanthem is on the ______

Answer 58

surface of the body

Question 59

Enanthems are found _________

Answer 59

in an orifice like the mouth

Question 60

Exantham and enathem are both usually caused by ______. What is a disease that exemplifies bouth

Answer 60

viruses, Hand Foot and mouth

Question 61

Phemphigus vulgaris