Derm Path

Question 1

Partial or complete loss of pigment producing melanocytes within the epidermis

Answer 1

Vitiligo

Question 2

Increased melanin pigment along basal layer of epidermis. No melanocytes hyperplasia. Become darker when exposed to sun

Answer 2

Freckle (Ephelis)

Question 3

Mask of pregnancy

Answer 3

Melasma

Question 4

Hyperpigmentation of face in pregnancy with increased melanin deposition along basal layer

Answer 4

Melasma epidermal type

Question 5

Hyperpigmentation of face in pregnancy due to melanin pigment in cytoplasm of macrophages

Answer 5

Melasma dermal type

Question 6

Benign linear melanocytes hyperplasia

Answer 6

Lentigo

Question 7

Nested proliferation of melanocytes at the dermo-epidermal junction

Answer 7

Junctional Benign Melanocytic Nevus

Question 8

Nested proliferation of melanocytes at the dermis only

Answer 8

Intradermal Benign Melanocytic Nevus

Question 9

Nevis with variability in pigmentation and irregular borders. Associated with malignant melanoma

Answer 9

Dysplastic Nevi

Question 10

Melanocytes positive for S-100 and HMB-45 antigens

Answer 10

Malignant Melanoma

Question 11

Radial growth of malignant melanoma

Answer 11

Superficial Type

Question 12

Superficial melanoma associated with sun damaged face in elderly

Answer 12

Lentigo Maligna

Question 13

Risk of metastasis is directly proportional to

Answer 13

Depth of invasion

Question 14

Round, flat, coin-like plaques with granular surface

Answer 14

Seborrheic Keratosis

Question 15

Proliferation of benign basaloid keratinocytes with hyperkeratosis and horn pseudocyst formation

Answer 15

Seborrheic Keratosis

Question 16

Thickened hyperpigemented areas are skin involving flexure areas

Answer 16

Acanthosis Nigricans

Question 17

Soft, flesh colored, bag-like tumor with stalk

Answer 17

Acrochordon (AKA skin tag or fibroepithelial polyp)

Question 18

Dermal or subcutaneous well-circumscribed, firm and movable nodules

Answer 18

Epithelial cysts (Wen)

Question 19

Flesh colored, dome-shaped nodules with a central keratin plug and resembles a crater

Answer 19

Keratoacanthoma

Question 20

Glassy eosinophilic cytoplasm

Answer 20

Kertaoacanthoma

Question 21

Rough sandpaper like lesions on sun exposed areas. May develop cutaneous horns

Answer 21

Actinic Keratosis

Question 22

Keratin pearls with intracellular bridges

Answer 22

Squamous cell carcinoma

Question 23

Pearly papules with telangiectasia

Answer 23

Basal Cell Carcinoma

Question 24

Most aggressive BCC

Answer 24

Morphea

Question 25

Malignant cells containing neurosecretory cytoplasmic granules

Answer 25

Merkel Cell Carcinoma

Question 26

Brown, tan, firm papules containing neoplastic fibroblasts and histiocytes

Answer 26

Benign Fibrous Histiocytoma

Question 27

Most common type of fibrous histiocytoma

Answer 27

Dermatofibroma

Question 28

Fibroblasts arranged in storiform (basket-weave pattern)

Answer 28

Dermatofibrosarcoma Protuberans

Question 29

Tumor like collection of foamy histiocytes within the dermis

Answer 29

Xanthoma

Question 30

Birbeck granules

Answer 30

Langerhans (histiocytosis X)

Question 31

Sezary syndrome, CD4 (+), Pautrier’s microabscesses

Answer 31

Mycosis Fungoides

Question 32

Dariers Sign, Mast cells

Answer 32

Mastocytosis