Derm Path Flashcards

1
Q

Partial or complete loss of pigment producing melanocytes within the epidermis

A

Vitiligo

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2
Q

Increased melanin pigment along basal layer of epidermis. No melanocytes hyperplasia. Become darker when exposed to sun

A

Freckle (Ephelis)

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3
Q

Mask of pregnancy

A

Melasma

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4
Q

Hyperpigmentation of face in pregnancy with increased melanin deposition along basal layer

A

Melasma epidermal type

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5
Q

Hyperpigmentation of face in pregnancy due to melanin pigment in cytoplasm of macrophages

A

Melasma dermal type

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6
Q

Benign linear melanocytes hyperplasia

A

Lentigo

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7
Q

Nested proliferation of melanocytes at the dermo-epidermal junction

A

Junctional Benign Melanocytic Nevus

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8
Q

Nested proliferation of melanocytes at the dermis only

A

Intradermal Benign Melanocytic Nevus

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9
Q

Nevis with variability in pigmentation and irregular borders. Associated with malignant melanoma

A

Dysplastic Nevi

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10
Q

Melanocytes positive for S-100 and HMB-45 antigens

A

Malignant Melanoma

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11
Q

Radial growth of malignant melanoma

A

Superficial Type

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12
Q

Superficial melanoma associated with sun damaged face in elderly

A

Lentigo Maligna

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13
Q

Risk of metastasis is directly proportional to

A

Depth of invasion

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14
Q

Round, flat, coin-like plaques with granular surface

A

Seborrheic Keratosis

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15
Q

Proliferation of benign basaloid keratinocytes with hyperkeratosis and horn pseudocyst formation

A

Seborrheic Keratosis

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16
Q

Thickened hyperpigemented areas are skin involving flexure areas

A

Acanthosis Nigricans

17
Q

Soft, flesh colored, bag-like tumor with stalk

A

Acrochordon (AKA skin tag or fibroepithelial polyp)

18
Q

Dermal or subcutaneous well-circumscribed, firm and movable nodules

A

Epithelial cysts (Wen)

19
Q

Flesh colored, dome-shaped nodules with a central keratin plug and resembles a crater

A

Keratoacanthoma

20
Q

Glassy eosinophilic cytoplasm

A

Kertaoacanthoma

21
Q

Rough sandpaper like lesions on sun exposed areas. May develop cutaneous horns

A

Actinic Keratosis

22
Q

Keratin pearls with intracellular bridges

A

Squamous cell carcinoma

23
Q

Pearly papules with telangiectasia

A

Basal Cell Carcinoma

24
Q

Most aggressive BCC

25
Malignant cells containing neurosecretory cytoplasmic granules
Merkel Cell Carcinoma
26
Brown, tan, firm papules containing neoplastic fibroblasts and histiocytes
Benign Fibrous Histiocytoma
27
Most common type of fibrous histiocytoma
Dermatofibroma
28
Fibroblasts arranged in storiform (basket-weave pattern)
Dermatofibrosarcoma Protuberans
29
Tumor like collection of foamy histiocytes within the dermis
Xanthoma
30
Birbeck granules
Langerhans (histiocytosis X)
31
Sezary syndrome, CD4 (+), Pautrier's microabscesses
Mycosis Fungoides
32
Dariers Sign, Mast cells
Mastocytosis