Derm Lecture 3 Flashcards
what is molluscum contagiosum?
a common pediatric virus caused by poxvirus, MCV-1 to -4
what is molluscum contagiosum caused by? occurs in who?
poxvirus, MCV-1 to -4
occurs in kids
molluscum contagiosum epidemiology
Primarily affects young children, sexually active adults and immunosuppressed
molluscum contagiosum clinical features
Non-pruritic flesh colored dome shaped papules 3-6 mm and have central depression
Curd like material can be expressed
where does molluscum contagiosum occur on the body?
Present anywhere, but classically over the face, trunk and extremities, and groin
how is molluscum contagiosum transmitted? where does virus replicate?
Transmitted by direct skin to skin contact (most easily in pools), gym equipment, and spread by autoinoculation
Virus replicates in epithelial cells
molluscum contagiosum dx
clinical exam/hx, punch biopsy
molluscum contagiosum tx
usually not necessary b/c self-limited & resolves in few months to few years (body develops antibodies)
- Avoid autoinoculation or transmission to close contacts
- Common goal of diff txt methods is the destruction of the lesions
Txts are not FDA approved:
- Topical Cantharadin (topical irritant)
- Cryotherapy (liq nitrogen)
molluscum contagiosum ddx
Warts (cauliflower appearance)
Milia (small collection of dead skin cells under the skin)
Veruca Vulgaris (common wart) epidemiology
Most common ages 5-20 y/o
(develop antibodies to this strain and then don’t develop as much, which is why seen at young age & not older people)
verruca vulgaris clinical features
Size is pinpoint to >1cm, papules with a rough grayish surface (“cauliflower type”; up close see finger like projections or papillae that stand up)
verruca vulgaris location on the body
- Hands & palms and periungul, nail folds, bottoms of feet
- Risk with frequent exposure to water
what is verruca vulgaris?
the common wart
what causes verruca vulgaris?
HPV
verruca vulgaris dx
clinical exam, punch biopsy (common to use for flat wart b/c can be hard to discern)
is no tx for verruca vulgaris an option?
Yes, no txt is an option b/c 65% of warts regress spontaneously w/in 2 yrs, but pts risk warts that may enlarge or spread to other areas
who is tx for verruca vulgaris recommended for?
-Txt recommended for pts w/extensive spreading, or symptomatic warts or warts that been present >2 yrs
what are the txs for verruca vulgaris?
- Cryotherapy
- Salicyclic acid/Cantharidin (topical vesicans)
- Occlusive dressing (promotes inflammation and then body attacks wart/virus)
- Intralesional injection of Bleomycin (LAST RESORT - for someone w/HIV or immunosuppressed – injectable chemo med that causes cell death
what is verruca plana?
flat wart
verruca plana epidemiology
children and young adults
verruca plana clinical features and location
2-4mm flat topped flesh colored papules
Location:
- Grouped together on face, neck, wrists, hands
what causes verruca plana?
HPV
dx of verruca plana?
clinical exam, punch biopsy (common to use for flat wart b/c can be hard to discern)
tx for verruca plana?
same as verruca vulgaris
- cryotherapy
- salicyclic acid/cantaridin
- occlusive dressing
- intralesional injection of Bleomycin (LAST RESORT for someone w/HIV or immunosuppressed)***
