Derm E1 Flashcards

1
Q

Environmental factors that can impact Acne

A

Emotional Stress
Repetitive Stress (such as using harsh soaps)
Occlusion and Pressure (via mechanical obstruction or makeup)
Heat and Humidity
Occupational acne (the chemicals you’re exposed to through your career path)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Relationship between foods and acne

A

very individuallized triggers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

home care for acne

A

gentle cleansers twice a day
wash with fingers
Do NOT use scrubs
use mild pH products
Use water-based lotions, cosmetics, and hair products

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What vehicles should be used with its corresponding type of skin texture?

A

Dry skin: lotions or creams
oily skin: gels or foams
hairy areas: foams

solutions are drying but can cover larger areas
Pledgets can cover larger areas as well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the factors acne treatment targets?

A

Follicular hyperproliferation
increased sebum production
c. acnes profilteraction (bacteria)
Inflammation
Androgen receptor inhibitor (the patho of acne is androgen can increase acne)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Isotrentinoin targeted treatment factors

A

Folicular hyperproliferation (oral and topical)
Increased sebum production (oral)
Inflammation (oral and topical)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Topical Retinoids NOT CI in prego

A

Topical trentinoin
Topical adapalene
Topical tazarotene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Benzoyl Peroxide ADE

A

Erythema
Scaling
Xerosus
Stinging/buring
Bleaching of hair/clothing
Reare reports of life threatening hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

OTC agents for Acne

A

Differin Gel, Adapalene
Tea Tree Oil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What acne treatments can not be used in prego

A

Hormonal agents
Topical retinoids
Oral antibiotics
Isotretinoin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Oral isotretinoin ddi

A

Tetracyclines
Doxycycline
Minocycline
Above can cause pseudotumor cerebri (increased cranial HTN)

Vitamin A supplements, can OD on vitamin A toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Acne Targeted Treatment Factors which Rx target - Follicular Hyperproliferation

A

Oral/Topical Retinoids
Azelaic acid
Salicylic Acid
Hormonal therapies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Acne Targeted Treatment Factors which Rx target - Increased Sebum Production

A

Oral Retinoids
Hormonal Therapies
Clascoterone cream

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Acne Targeted Treatment Factors (5)

A

Follicular Hyperproliferation
Increased Sebum Production
C. Acne’s Proliferation
Inflammation
Androgen Receptor Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Acne Targeted Treatment Factors Rx that target - C, Acnes proliferation

A

Benzoyl Peroxide
Antibiotics
Azelaic acid
Dapsone topical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Acne Targeted Treatment Factors Rx that target - Inflammation

A

Oral/Topical Retinoids
Oral tetracyclines
Azelaic acid
Clascoterone cream
Dapsone topical

17
Q

Acne Targeted Treatment Factors Rx that target - Androgen Receptor Inhibitor

A

Clascoterone cream

18
Q

Pharmacist’s Role in Drug-Induced Dermatologic Disorders

A

Identify culprit drug
Identify cross-reacting drugs to also avoid
Select alternative treatments for the patients underlying disorder
Educate patients and care givers about drug avoidance in the future
Differentiate and triage mild and serious drug eruptions
Provide pharmacotherapy recommendations for treating DIDD including supportive care measures
Develop monitoring plans for patients with DIDD

19
Q

maculopapular rash offending agents

A

penicillins/cephalosporins
Sulfonamides
Anticonvulsants (barbiturates such as phenobarbital, phenytoin, carbamazepine, lamotrigine)

20
Q

DRESS offending agents

A

ALLOPURINOL

Sulfonamides
Anticonvulsants - barbiturates (phenobarbital), phenytoin, carbamazepine, lamotrigine
Dapsone

21
Q

DRESS risk factors

A

Excessive allopurinol dose (>1.5 * eGFR as the mg/day max)
renal dysfunction
Concomitant thiazide diuretic
HTN
Asian ethnicity
HLA-B * 58:01

22
Q

Urticaria offending agents

A

Penicillins and related antibiotics
Sulfonamides
Aspirin
Opiates
Latex

23
Q

Serum sickness-like reactions offending agents

A

Penicillins/cephalosporins
Sulfonamides

24
Q

Fixed drug eruptions offending agents

A

Tetracyclines
Barbiturates
Sulfonamides
Codeine
Phenolphthalein
Acetaminophen
NSAIDs

25
Q

SJS/TEN risk factors

A

HIV infection

Lupus (SLE)
Malignancy
UV light or radiation therapy
HLA-B*15:02

26
Q

SJS/TEN offending agents

A

Sulfonamides
Penicillins
Anticonvulsants: phenytoin, carbamazepine, barbiturates, lamotrigine
NSAIDs (particularly the “-oxicams”)
Allopurinol

27
Q

Drugs causing hyperpigmentation

A

Phenytoin
Tetracyclines, silver, mercury, anti malarial
Amiodarone

28
Q

Drugs causing photosensitivity offending agents

A

Sulfonamides
Tetracyclines
Amiodarone
Coal tar