derm

Question 1

What is the HLA-B*1502 allele associated with?

Answer 1

Carbamezapine-induced SJS/TEN

Question 2

What is the HLA-B*5801 allele associated with?

Answer 2

Allopurinol-induced SJS/TEN

Question 3

What is the CYP2C9*3 enzyme associated with?

Answer 3

Phenytoin-induced SJS/TEN

Question 4

List the active ingredients in:

1. Off! Clip-On
2. Tiger balm mosquito repellent patch
3. Ultrathon insect repellent 8
4. Moz Away long hour protection

Answer 4

1. Metofluthirin
2. Eucalyptus citriodora oil
3. DEET
4. Picaridin

Question 5

How long do malaria symptoms take to appear?

Answer 5

Anytime between 7 days to 1 year

Question 6

DEET 10% and 24% repellents are effective for approximately how long, respectively?

Answer 6

2 hours and 5 hours respectively

Question 7

What insect repellent ingredients are EPA-registered?

Answer 7

1. DEET
2. Picaridin
3. Eucalyptus oil
4. IR 3535

Question 8

List 2 side effects of benzoyl peroxide

Answer 8

1. Bleaches the hair or fabric

2. Skin irritation (e.g. burning, stinging)

Question 9

What common side effects do Differin and Doxycycline have?

Answer 9

Photosensitivity

Question 10

List at least 5 drugs that are associated with SJS/ TEN

Answer 10

1. Allopurinol
2. Lamotrigine
3. Phenytoin
4. Carbamazepine
5. Sulfamethoxazole
6. NSAIDs
7. Sulfasalazine
8. Amoxicillin
9. Ciprofloxacin
10. Levofloxacin
11. Doxycycline

Question 11

List at least 5 risk factors for SJS/ TEN

Answer 11

1. HIV infection
2. UV light/ radiation therapy
3. SLE
4. Contrast medium
5. Graft-vs-host disease after bone marrow transplantation
6. External chemical exposure

Question 12

Retacnyl is just as efficacious as Oratane/ Roaccutane/ Nimegen but is more irritating to the skin. True or false?

Answer 12

False. Retacnyl (tretinoin) is less irritating to the skin compared to Oratane/ Roaccutane/ Nimegen (isotretinoin)

Question 13

List at least 5 side effects of Oratane/ Roaccutane/ Nimegen

Answer 13

1. Dry lips - use lip balm
2. Dry eyes - use eye drops
3. Dry nose - use petroleum jelly or Neilmed nasogel
4. Dry skin - use moisturiser
5. Photosensitivity - use sunscreen

Question 14

What is the active ingredient of Dermovate?

Answer 14

Clobetasol propionate

Question 15

What is the active ingredient of Neoderm?

Answer 15

Betamethasone dipropionate
Clotrimazole
Gentamicin

Question 16

What is the dosing of Regro, Growell and Regaine (in terms of mL and no. of pumps)

Answer 16

1mL for all

Regaine: 6x
Regro: 7x
Growell: 8x

Question 17

What are some side effects of minoxidil?

Answer 17

• Temporary hair loss (first 1-2 months)
• Unwanted facial/ body hair
• Scalp irritation (e.g. dryness, scaling, itching)
• Headache
• Rashes, itching
• Swelling of hands, face, ankles or stomach
• Difficult of laboured breathing

Question 18

On which areas of the body does plaque psoriasis commonly affect?

Answer 18

Extensor elbow, knees, scalp and gluteal cleft

Question 19

On which areas of the body does guttate psoriasis commonly affect?

Answer 19

Trunk and proximal extremities