Derm Flashcards
Atopic eruption of pregnancy 3 types
Eczema
Prurigo of pregnancy
Pruritic folliculitis of pregnancy
Pathophysiology of increased eczema in pregnancy
Dominant humoral immune response and T-helper 2 cytokines production
Incidence of prurigo of pregnancy
1:300
Appearance of prurigo
Pruritic, often excoriated papules and nodules on the extensor surfaces of the legs and upper arms; abdo can be involved
Any trimester
Pathogenesis unknown
No adverse effects to mother or fetus
Pruritic folliculitis
1::3000
2nd. And 3rd trimester
Mildly. Itchy
Looks like. Acne (2-4mm follicular papules or pustules. Typically on shoulders, upper back, arms I,, chest, and abdomen
No risk to mum or babe
Polymorphic eruption of. Pregnancy
1:160
Associated with multiple gestation and maternal weight. Gain.
Etiology unknown
Usually nullip third trimester
Doesn’t usually recur
Polymorphous, erythematous, nonfollicular papules, plaques, and sometimes vesicles
Abdomen, can. Spread to upper thighs, breasts, and arms; (Umby sparing)
Pemphigoid gestationis
Rare autoimmune disorder
1:50000
Second or third trimester
Rash in peri-umbilical region
Lesions are pruritic, urticaria last and vesiculobullous
Immunopathological-complement 3
5-10% fetuses have urticarial, vesicular or bullies lesions
Some association with prem deliveries and SGA
Treat with antihistamines and/or steroids
Sometimes need igG immunoglobulins