DERM Flashcards

1
Q

What are Beau’s lines

A

Self limiting trasnverse ridges that occur on the nails
Caused by temporary interference with nail formation
Diseases: pneumonia, diseases with prolonged fever,

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2
Q

Clubbing causes:

A

CVS: cyanotic ongenital heart disease, endocarditis, atrial myxoma, aneurysms,

RESP: bronchogenic carcinoma, chronic lung suppuration, fibrosing alveolitis, mesothelioma, TB

GI: crohns, UC, cirrhosis, gi lymphoma, coeliac diseases

Rare: thyroid acropachy, oesophagel carcinoma

Idiopathic clubbing

NOT COPD !!!!!!!!!!!!!

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3
Q

What is a cause of hirsutism

A

PCOS

adrenal/ovarian tumours
cushing's
acromegaly
congenital adernal hyperplasia
androgen/costicosteroid therapy
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4
Q

Which drug is known to cause alopecia?

A

Warfarin

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5
Q

With which malignancy is acanthosis nigricans commonly associated with?

A

Gastrointestinal malignancies

PCOS
obesity
acromgaly
Diabetes
thyroid disease
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6
Q

With which condition is dermatitis herpetiformis associated with?

A

Coeliac disease

Intense, itchy blisters on elbows, knees or buttocks

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7
Q

With which condition is pyoderma gangrenosum associated with?

A

Crohns. UC

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8
Q

What is Steven Johnson syndrome?

A

Steven-Johnson syndrome is a severe form of erythema multiforme with bullous lesions and necrotic ulcers

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9
Q

With which condition is lupus pernio associated with?

A

Sarcoidosis

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10
Q

What is tuberous sclerosis?

A

An AD condition characterized by triad of cutanoues abnormalities, mental retardation and seizures

Skin lesions: ash-leaf hypopigmentation, periungual fibromata, shagreen patches, adenoma sebaceum

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11
Q

How will cellulitis classically present?

A

Pt will present with a painful, red area with a history of a cut happening in that area “gardening the other day”

OE: erythematous, oedematous, warm, indistinct margins, pyrexia

can be orbital and periorbital aswell

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12
Q

Which organisms commonly cause cellulitis?

A

Streptococcus Pyogenes
Staph Aureus

Orbital: haemophilus influenzae

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13
Q

What is lupus vulgaris

A

A cutaneous manifestation of Mycobacterium Tuberculosis
It has a classic jellylike reddish-brown glistening plaques apperance
It’s usually found on the head and neck
It keeps growing
If left untreated it can possibly turn malignant
On Bx you will see tuberculoid granulomata.

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14
Q

What are the 4 types of malignant melanoma and their prelevance

A

Superficial spreading 70% - from pre existing mole, radial expansion
Nodular 15% - de novo, agressive
Lentigo Maligna 10% - flat, on face, elderly
Acral Lentigous 5% - on palms, soles

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15
Q

What is Mycosis fungoides

A

Mycosis fungoides - looks like a fungal infection but is in fact a cutaneous T-cell lymphoma)
Often confused with psoriatic plaques on chest and back - erythematous.

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16
Q

Describe the classic appearance of arterial ulcers

A

“punched out appearance”
elliptical
well defined edges

17
Q

Where are arterial ulcers found

A

dorsum of foot

between toes

18
Q

What are common risk factors for arterial ulcers

A
coronary heart disease
stroke/tia history
DM !!
Peripheral arterial diseases
Obesity
Immobility
19
Q

Classic presentation of pt with arterial ulcer

A

Ulcer on dorsum of foot
WORST AT NIGHT !!!!
Generally worst when lying flat (due to a further decrease in arterial blood supply to the are)
Relieved by dangling foot over edge of bed.

20
Q

Wing shaped red rash on face?

A

SLE

“butterfly rash”

21
Q

Which drugs can commonly cause an SLE-like syndrome and present with a butterfly rash

A

Sulphonamides (antibiotics)

22
Q

What is a nodule

A

A solid lump greater than 0,5cm in diameter which may be SC or intradermal

23
Q

Which skin changes are typically seen in DM pts

A

Neuropathic ulcers
Necrobiosis lipoidica
Acanthosis Nigricans
Lipohypetrtophy