Derm

Question 1

Drugs inducing TEN

Answer 1

phenytoin
sulphonamides
allopurinol
penicillins
carbamazepine
NSAIDs

Question 2

TOxic epidermal necrolysis management

Answer 2

stop precipitating factor
supportive care, often in intensive care unit
intravenous immunoglobulin has been shown to be effective and is now commonly used first-line
other treatment options include: immunosuppressive agents (ciclosporin and cyclophosphamide), plasmapheresis

Question 3

Erythema multiforme causes

Answer 3

viruses: herpes simplex virus (the most common cause), Orf*
idiopathic
bacteria: Mycoplasma, Streptococcus
drugs: penicillin, sulphonamides, carbamazepine, allopurinol, NSAIDs, oral contraceptive pill, nevirapine
connective tissue disease e.g. Systemic lupus erythematosus
sarcoidosis
malignancy

Question 4

Cherry hemangioma features

Answer 4

Cherry haemangiomas (Campbell de Morgan spots) are benign skin lesions which contain an abnormal proliferation of capillaries. They are more common with advancing age and affect men and women equally.

Features
erythematous, papular lesions
typically 1-3 mm in size
non-blanching
not found on the mucous membranes

As they are benign no treatment is usually required.

Question 5

Actinic keratosis mx

Answer 5

prevention of further risk: e.g. sun avoidance, sun cream
fluorouracil cream: typically a 2 to 3 week course. The skin will become red and inflamed - sometimes topical hydrocortisone is given following fluorouracil to help settle the inflammation
topical diclofenac: may be used for mild AKs. Moderate efficacy but much fewer side-effects
topical imiquimod: trials have shown good efficacy
cryotherapy
curettage and cautery