Derm Flashcards
transient vascular phenomena
- first 2-3 wks of life
- secondary to cold stress
- resolves w/ warming of skin
- associated w/ acrocyanosis and cutis marmorata
acrocyanosis
- hands and feet symmetrically blue
- no edema or other cutaneous findings
cutis marmorata
- reticulated cyanosis
- symmetrical to trunk and extremities
- can mimic CMTC which is persistent
erythema toxicum neonatum
-MC pustular rash
-2nd - 3rd day of life
2-3 mm erythematous, blotchy macs/paps, evolve into pustules on broad erythematous base
-“Flea bitten”**
- on face, trunk, and proximal extremities
transient neonatal pustular melanosis (TNPM)
- MC in black males
- usu present at birth
- small pustules on non erythematous base
- leave hyperpigmented macules w/ collarette of fine scale
acropustulosis of infancy
- chronic or recurrent pustular eruption in newborn or early infancy
- esp on palms and soles, but can be widespread
- episodic w/ remissions q 1-3 wks but resolves by 2-3 yrs
- significant pruritus***
which eruption resembles scabies?
acropustulosis of infancy
miliaria crystallina
- obstruction to flow of sweat (eccrine duct obstruction)
- tiny vesicles on non-inflamed skin
miliaria rubra
- small paps/vesicles or pustules w/ erythema
- obstruction is deeper** in epidermis than crystallina
- a response to thermal stress and resolves w/ cooling of skin
- common in first few weeks of life secondary to eccrine duct immaturity
neonatal/infantile acne
- avg onset 3 wks but can be delayed to 3-6 mos
- inflammatory red paps/pustules, rarely cysts
- tx non usu necessary but topical acne preps or ketoconazole can be used in neonates
suggested causes of neonatal and infantile acne
- neonatal: inflammatory rxn to malassezia
- infantile: likely triggered by endogenous androgens
diaper dermatitis
- irritant is MC
- contact w/ irritants leads to erythema, scale and often erosion
- intertriginous areas usu spared**
tx of diaper dermatitis
- gentle cleansing
- use of lubricants/barrier pastes
- may need low potency steroid ointment
- avoid offending agent w/ contact derm
diaper candidiasis
- brilliant red eruption w/ sharp borders and satellite red paps or pustules
- intertriginous areas typically involved**
- topical antifungals to tx
oral candidiasis (thrush)
- newborns may acquire from contact w/ vaginal tract and infants following abx tx
- white dots or patches and plaques; rubbing of lesions leaves a red spot and occasional superficial bleeding erosions
- MC on buccal mucosa, tongue and soft palate
- tx: nystatin or fluconazole
capillary malformations
- salmon patch
- port wine stain
salmon patch
- innocent pink to red macule on nape of neck (stork bite), glabella (angel’s kiss), forehead, upper eyelids, sacrum
- if on face, usu fades during 1st year but may persist indefinitely on neck/sacrum
port wine stain
- persist during childhood; darkens and thickens in adolescence and adulthood
- gradual hypertrophy to underlying soft tissue
- unilateral to head/neck MC
complications of port wine stain
- involvement to 1st division trigeminal nerve associated w/ Sturge-Weber syndrome
- may involve underlying meninges, cerebral cortex/eye; seizures, mental retardation, hemiplegia, glaucoma
tx of port wine stain
pulsed dye laser - recurrence possible
venous malformation
- slow flow venous abnormality of lg dilated vascular channel
- superficial blue or purple paps/nodules; deeper lesions w/ subtle blue hue at surface w/ compressible ropy texture
arteriovenous malformation
- route from artery to vein, bypassing the capillary bed (uncommon)
- fast flow anomaly
- tense vascular mass; overlying skin is purple-ish, warmer, hair may grow faster and affected limb may be larger; possible palpable thrill or bruit
- US or MRI to evaluate
infantile hemangioma
- dome shaped, dull to bright red
- generally grow over the first year, remain stable for period of months, then slowly involute spontaneously
- most require no tx
involution of infantile hemangioma
- streaks or islands of white appear w/i as the lession flattens
- possible ulcerations
complications of infantile hemangioma
- can compromise vital fxn if located near anus, urethra, airway or eyes
- if > 5 cutaneous lesions it could indicate visceral involvement
- associated w/ extra cutaneous syndromes (vertebral, spinal, GU abnormalities)
- massive ones on the face/scalp have been associated with PHACE syndrome (posterior fossa brain malformations, arterial anomalies, cardiac defects, eye defects)
mongolian spots
- poorly circumscribed, gray to blue congenital macules or patches usu on trunk / proximal extremities
- AA>Asian>Caucasian
- no tx, usu fade by 3-5 yrs
epidermal nevi
- most appear at brith or early infancy
- localized, linear**, verrucous, hyperpigmented plagues
sebaceous nevus
- linear, crescent, or round hairless, yellow, smooth to cobblestone-like plaque usu on scalp*
- benign hypertorphy and warty nodules expected around puberty
- <1% can lead to BCC
- elective excision can be delayed until after puberty
congenital pigmented nevi
- pigmented macules/plaques at birth or first few mos of life
- often develop dense hair growth
- small dark macules/paps may appear w/i
giant congenital pigmented nevi
- 20 cm or more
- 2-15% incidence of melanomas developing in them
angiofibroma
- small reddish-brown paps on face
- solitary in healthy individual but numerous are associated w/ tuberous sclerosis
tuberous sclerosis
genodermatosis associated w/ triad of angiofibromas, epilepsy and mental retardation