Derm Flashcards
Hypersensitivity is a___ mediated reaction that produces _____ on the skin.
IgE mediated
Hives/urticaria
Describing hives:
Erythematous, raised, evanescence wheals
Sometimes hives are not itchy
For kids over _____ kg, you give the adult Epi pen.
30 (65lbs)
Hives cocktail
Epinephrine
Systemic steroids (2-3 days)
Antihistamines (Benadryl 1st line, cetirizine, Claritin preferred over hydroxyzine)
H2 blockers (famotidine)
Drug eruptions usually most closely mimic _____ however tend to be more dense with mono-posterior lymphadenopathy. Starts on the trunk and spreads to extremities. It can also mimic _____ which is usually on extremities and flexor surfaces.
Measles
Strep rash
Chief offenders for drug eruption rash?
Amoxicillin, NSAIDS, PCN, cephalosporins, sulfonamides (bactrim), anticonvulsants, antifungals.
Diaper area is usually ____ in atopic dermatitis due to moisture held in the area.
Spared.
Antihistamines don’t work for the itching involved with atopic dermatitis because _____
It’s not IgE mediated
_____ are better than creams because they’re more potent and stay on longer. Creams are better than _____
Ointments
Lotions.
Least potent OTC steroid?
Hydrocortisone 1% ointment
If you don’t taper higher doses of steroids in the tx of AD, what can happen?
Rebound itching.
Non-steroidal medications for atopic dermatitis
TCI (topical calcineurin inhibitors) - Pimecrolimus, Tacrolimus (elidel) >2yrs
PDE4 (phosphodiesterase T4 inhibitors) - Eucresia >2yrs expensive.
What are the main offending agents for super imposed infections on AD?
Tx?
Staph aureus and GAS. - mupirocin.
HSV
Diluted bleach baths.
When would you recommend a diluted bleach bath in AD?
With a superimposed bacterial infection. 10mins soak 2-3x/week.
1/8-1/2 cup bleach per standard bath tub.