derm Flashcards

1
Q

what are the features of erythema multiforme?

A

Target lesions initially seen on the back of the hands / feet before spreading to the torso.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the most common cause of erythema multiforme ?

A

Herpes simplex virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what drugs cause erythema multiforme

A

Penicillin
Allopurinol
Sulphonamides
Carbamazepine
Oral contraceptive pill
NSAIDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are the other causes of Erythema Multiform?

A

Connective tissue disease : SLE
Sarcoidosis
Malignancy
Bacteria like mycoplasma and Streptococcus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is erythema multiforme major ?

A

It is the most severe form of erythema multiforme and is associated with mucosal involvement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how does erythema nodosum present?

A

Tender, erythematous nodular lesions occurring on the shins primarily

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the causes of erythema nodosum ?

A

infections such as ( Streptococci, TB, Brucellosis)
Systemic disease : Sarcoidosis, IBD, Behcets
malignancy
drugs such penicillins, sulphonamides COCP
pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is guttate psoriasis precipitated by?

A

streptococcal infection 2-4 weeks prior to lesions appearing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the features of guttate psoriasis ?

A

Tear drop papules on the trunk and limbs that spontaneously resolve within 2-3 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is pityriasis rosea ?

A

Acute, self limiting rash tending to affect young adults presenting with a herald patch followed later by multiple erythematous raised lesions with a minority having a history of a recent viral infection.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what conditions are associated with Acanthosis Nigricans ?

A

type 2 diabetes
GI cancer
Obesity
PCOS
Acromegaly
Cushing’s disease
Hypothyroidism
Prader Willi
drugs like COCP and nicotinic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How does Lichen Planus present

A

Itchy papular rash most commonly on palms, soles, genitalia and flexor surfaces with ‘‘white lines’’ pattern

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is the management of Lichen planus?

A

Potent topical steroids
Benzydamine mouthwash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are the features of rosacea ?

A

affecting the nose, cheeks and forehead
flushing
telangiectasia
this can develop into persistent erythema with papules and pustules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

explain the stepwise management of rosacea ?

A

high factor sunscreen
Flushing :topical brimonidine gel
mild to moderate pustules and papules : topical ivermectin
Moderate to severe : Combination of topical ivermectin and oral doxycycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How does seborrhoeic dermatitis present? How is it managed?

A

eczematous lesions on the sebum rich areas : Scalp, periorbital, auricular and nose.
managed with ketoconazole 2% shampoo
Steroids can be used for short bursts of face and body management.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what are 2 conditions associated with seborrhoeic dermatitis?
What are 2 complications of seborrhoeic dermatitis?

A

HIV , Parkinson’s
otitis externa and blepharitis may develop

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what are the different types of acne lesions usually seen in each patient ?

A

Comedones : closed is a whitehead, open is a blackhead

Inflammatory lesions : pustules and papules

nodules and cysts

scars such as ice-pick and hypertrophic scars

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is acne fulminans?

A

Very severe acne associated with systemic upset

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

how is acne classified?

A

Mild : Open and closed comedones without inflammatory lesions.

Moderate : widespread inflammatory lesions and pustules and papules

Severe acne: extensive inflammatory lesions including nodules, pitting and scarring.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

How is mild-moderate acne managed?

A

12 week course of topical combination therapy :

topical adapalene and benzoyl peroxide
topical tretinoin and clindamycin
topical benzoyl peroxide with clindamycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what is the management of moderate to severe acne?

A

add oral lymecycline / oral doxycycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what is eczema herpeticum? How does it present? How is it managed?

A

Caused by herpes simplex virus 1 or 2.
Rapidly progressing rash with erosions.
Admit to hospital and treat with IV Acyclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what causes pityriasis rosea

A

HHV-7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
how does eczema present?
Itchy erythematous rash exacerbated by repeated scratching. typically on the extensor surfaces in kids and flexor surfaces in adults
26
How is eczema managed?
simple emollients topical steroids ( starting with hydrocortisone, betamethasone, fluticasone, clobetasol)
27
How does Chronic plaque psoriasis present?
Presents as erythematous red scaly plaques covered with a silvery white scale typically seen on extensor surfaces with a clear distinction between normal and affected skin.
28
what is Auspitz sign
If the scale is removed, a red membrane with pinpoint bleeding points may be seen
29
what are the different types of psoriasis?
Flexural : smooth skin pustular psoriasis : palms and soles
30
what factors can exacerbate psoriasis
trauma alcohol drugs such as : Beta blockers, lithium, antimalarials ( hydrochloroquine and hydroxychlorquine), NSAID's ACEi, Infliximab
31
what is the stepwise management of psoriasis?
regular emollients first line : Potent corticosteroids OD + vitamin D analogue second line : apply vitamin D analogue twice daily third line : increase application of potent corticosteroid to twice daily
32
what are the different forms of tinea?
Tinea capitis : Scalp Tinea corporis : trunk, legs or arms tinea pedis : feet
33
what is actinic keratosis ? How and where does it present ? How do you manage it ?
Common premalignant skin developing as a consequence of chronic sun exposure. features include : small, crusty or scaly lesions that may be pink, red, brown or the same colour as the skin. these typically occur on sun exposed areas such as the temples of the head. Management options include : sun avoidance and sun cream Fluoruracil cream hydrocortisone
34
what are keloid scars? What are its predisposing factors ? how do you treat it ?
Keloid scars are tumour-like lesions arising from the connective tissue of a scar and extending beyond the dimensions of the original wound. Predisposing factors include : ethnicity : more common in people with dark skin young persons they are treated initially with intra-lesional steroids excision is sometimes recquired
35
what are the main organisms causing fungal nail infections? What are the risk factors for it ? What are its features?
Dermatophytes : Trichophyton Yeasts : Candida risk factors include : Age DM Psoriasis trauma it presents as ''unsightly nails'' thickened rough and opaque nails
36
when should early intubation be considered in the management of burns?
Smoky inhalation resulting in airway oedema Consider early intubation
37
How do you manage acne vulgaris in pregnancy?
Oral erythromycin
38
How are pressure ulcers graded?
Grade 1 : skin is intact with skin discolouration Grade 2 : partial thickness loss Grade 3 : Full thickness skin loss but does not extend down to underlying fascia Grade 4 : Extensive destruction and damage
39
what is the school exclusion advice for Lice
not advised
40
what are the treatment options for head lice? When is it recommended?
treatment is recommended only if live lice is found. treatment options include : Malathion wet combing dimeticone isopropyl cyclomethicone
41
which bacteria can cause acne vulgaris?
Propionibacterium acnes
42
what is the most common malignancy in the lower lip? How is i t managed?
SCC Manage with Mohs micrographic surgery
43
how is treatment of household contacts advised in the management of scabies?
household contacts should also be treated with permethrin and receive 2 doses.
44
what are the exclusions regarding impetigo?
patients are no longer contagious when they have been on treatment for 48h / all lesions have crusted over.
45
what options are used for the management of scabies?
Permethrin 5% Malathion 0.5%
46
where does eczema primarily occur in infants?
face and neck
47
what is the management of urticaria?
first line : non-sedating anti-histamines such as loratadine / cetirizine second line : Sedating anti-histamine like chlorphenamine prednisolone for severe/ resistant episodes
48
what chart is used to assess burns
Lund and Browder
49
How does Bowen's disease present?
red scaly patch, slow growing and occurring on head, neck, lower limbs
50
what are the features of polymorphic eruption of pregnancy ?
pruritic condition associated with last trimester with lesions appearing in abdominal striae with peri-umbilical sparing.
51
seborrhoeic dermatitis is due to which fungi
Malassezia furfur
52
explain bullous pemphigoid and pemphigus vulgaris?
auto-immune condition characterised by itchy tense blisters with no mucosal involvement whereas pemphigus vulgaris key presenting feature is mucosal involvement
53
how does pemphigoid gestations present?
rash starting in the peri-umbilical area and causes blisters.
54
what is molluscum contagiosum caused by? How does it present? What is the advice around management ?
it is caused by Poxvidiridae. It presents with characteristic pinkish or pearly white papules with central umbilication appearing in clusters anywhere on the body except palms of hands and soles of the feet. treatment is generally not required.
55
how is hirsutism assessed and managed?
Ferriman-Gallwey scoring system Managed by weight loss, COCP such as co-copyrindol and yasmin
56
what is the advice given to patients with shingles?
People with shingles should be advised that they are infectious until the vesicles have crusted over, usually 5-7 days following onset
57
what is hidradenitis supporativa
Hidradenitis suppurativa is a chronic, painful, inflammatory skin disorder is characterized by nodules, pustules, sinus tracts, and scars in intertriginous areas it occurs most commonly in the Axilla and other areas include inguinal, inner thighs, perineal and perianal areas risk factors include family history, smoking, obesity, diabetes etc
58
what analgesics can be used in the management of shingles
Paracetamol and NSAIDs neuropathic pain oral corticosteroids
59
under what circumstances are antivirals not prescribed in shingles?
< 50 mild truncal rash only
60
what is milia and how does it present
small benign keratin filled cysts typically appearing around the face
61
how does strawberry Naevus present and how does one manage it ?
erythematous, raised and multilobed tumours that increase in size until the age of about 6-9 months before regressing.
62
what are the causes of pyoderma gangrenosum?
Idiopathic Auto-immune : UC, Crohns,RA, SLE, PBC haematological : myeloproliferative, lymphoma, leukaemia granulomatosis with polyangiitis
63
which structures do antibodies target in pemphigus
desmosomes
64
how does one differentiate spider naevi from telagiectasia
Spider naevi fill from the centre on pressing while telangiectasia fill from the edge
65
what is erysipelas? How would you distinguish it from cellulitis? How would you manage it ?
It is a localised skin infection caused by streptococcus pyogenes and is a more superficial limited version of cellulitis. It can be distinguished from cellulitis as it presents with raised and well-defined borders. Managed with Flucloxacillin
66
what is seborrheic keratoses? How does it present and how is it managed?
benign epidermal skin lesions seen in older people. features include : flesh to light brown to black stuck on appearance - kind of like rotten cauliflower managed conservatively or removed
67
how are venous ulcers investigated and managed
investigations ABPI ( normal 0.9-1.2) management compression bandaging oral pentocifylline
68
how is hyperhidrosis managed?
first line : Topical aluminium chloride iontophoresis botolunim toxin - armpits surgery
69
chondrodermatitis nodularis helicis
looks like actinic keratosis but is painful
70
how to distinguish pityriasis rosacea and guttate rosacea
pityriasis rosacea : viral infection precedes guttate psoriasis : strep precedes
71
what is leucoplakia and how does it present?
premalignant condition which presents as white, hard spots on the mucous membranes of the mouth. It is more common in smokers.
72
how are toenail infections managed
not bothering - leave as is dermatophyte/ candida limited involvement : amorolfine topical more extensive due to dermatophyte : oral terbinafine more extensive due to candida : oral itraconazole
73
what is the most common cutaneous sign in anti-phospholipid syndrome and how does it present ?
Livedo reticularis presenting as purplish lace patterned discolouration