Derm Flashcards
Which of the following histologic patterns of inflammatory skin disease would be most likely associated with clinically detectable depigmentation:
Interface dermatitis
Which of the following is/are true regarding panniculitis?
a) Refers to inflammation targeting the subcuticular adipose layer of the skin
b) The lesions are often nodular and drain to the surface
c) Is a condition in cats commonly caused by atypical mycobacterial organisms
d) In some animals, the condition can be a sterile, idiopathic condition
Which of the following would be the least likely to lead to clinical and microscopic lesions of a nodular to diffuse dermatitis in a dog?
An ischemic dermatopathy
Which of the following is a common mechanism of acantholysis?
Immune mediated destruction of proteins needed for cell to cell attachment
Which of the following is an example of secondary lesion?
Scale
Which of the following is an example of primary lesion?
Nodule
Which of the following is a common pathogenesis of lesion formation in vasculitis?
Immune mediated Type III hypersensitivity reaction (antigen-antibody complex formation)
Which of the following conditions can be a manifestation of underlying liver disease?
Superficial Necrolytic Dermatitis (SND)
Vesicles and bullae can form by which of the following mechanism/s?
a. Thermal injury
b. Friction
c. Immune mediated destruction of cell to cell or cell to substrate proteins
d. Severe ballooning degeneration of keratinocytes
The three most common causes of folliculitis in dogs are:
Follicular dwelling Demodex mites, Staphylococcal bacteria and dermatophytes
The pemphigus complex of diseases was used in class as classic examples of what category of inflammatory skin disease?
Vesicular or pustular
most common pathogenesis for lesion development in cases of an interface dermatitis is:
Damage to components of the basal cell layer of the epidermis or other component located at the dermal epidermal junction.
most common pathogenesis for lesion development in cases of a perivascular dermatitis is:
A nonspecific hypersensitivity response
Subcorneal pustules eventuate into:
Crusts
Pemphigus Foliaceus:
a. The most common autoimmune skin disease seen in the dog.
b. Characterized clinically by pustules and crusts.
c. characterized by a salient histological finding of acantholytic keratinocytes within the epidermis and sometimes follicular walls.
d. A common differential for superficial pyoderma in the dog.
Pautrier’s microabscesses:
are microscopic accumulations of neoplastic lymphocytes within the epidermis and are seen in cases of epitheliotropic lymphoma (aka- Mycosis Fungoides).
Atrophic dermatoses that present with bilaterally symmetrical lesions are most often due to:
Hormonal imbalance
example of focal atrophic dermatosis (dermatitis) caused by a vascular lesion that occurs most often in small breed dogs is:
Rabies vaccine associated lymphocytic vasculitis
- A condition used as an example of an interface dermatitis that features transepidermal apoptosis of keratinocytes and is represented clinically by target form or arciform, linear or serpiginous erosive lesions affecting the groin, axilla, the trunk or concave surface of the pinna is:
c. Erythema Multiforme (EM)
What causes the formation of pustules in pemphigus foliaceus?
Loss of cohesion between keratinocytes due to the breakdown of cell to cell attachments
Loss of cohesion between keratinocytes due to the breakdown of cell to cell attachments
Pustules
Which of the following is most likely to precede the development of calcinosis cutis?
naturally occuring hyperadrenocorticism & iatrogenic hyperdrenocorticisim
The biopsy should be performed so that the primary lesions are in the center of the biopsy sample.
True
biopsy of completely ulcerated areas will prevent the diagnosis of which of the following?
emphigus foliaceus
b. Erythema multiforme
c. Superficial necrolytic dermatitis (hepatocutaneous syndrome)
d. Ichthyosis
