Derm 1 Flashcards
Eczematous dermatitis
Tx
Acute: topical corticosteroids, antihistamines for itching. Topical calcineurin inhibitors to avoid steroids. Prevent: daily emollients, avoid irritants, phototherapy, bleach baths to avoid 2ry infxn
Dyshidrosis (eczema)
Tx
Topical steroids (ointments), cold compresses, Burrow’s solution
Lichen simplex Tx
Avoid scratching/rubbing, high strength topical steroids, antihistamines
Drug eruptions (fixed) Tx
Drug avoidance & antihistamines
Lichen planus Tx
Most remit spontaneously in 1-2 yrs Topical corticosteroids (clobetasol, betamethasone) Intralesional injections of triamcinolone Generalized: PO steroids. Oral: paste. Phototherapy
Pityriasis rosea
Tx
Symptomatic Patient education -benign lasts 4-10wks
Psoriasis Tx
All forms: sun exposure, sea bathing, moisturizers, relax, Tar, salicylic acid lotion Determine severity→ Mild/mod <5% BSA. Severe >5% BSA Mild/Mod: Intermittent therapy-topical corticosteroids, vit D analog, tazarotene (retinoid) Continuous-Calcineurin inhib (tacrolimus) Severe: systemic tx (Methotrexate, cyclosporine, biologics (-mabs))
Erythema multiforme
Tx
Usu resolves spontaneously in 3-5 weeks Stop any drug related cause Oral antihistamine and steroids for sx’s Recurrent/prophylaxis: PO acyclovir
Stevens - Johnson syndrome
Tx
Withdrawal agent, transfer to burn unit if severe necrolysis, manage fluid and electrolyte IVIG, Corticosteroids, antibiotics debateable
Toxic epidermal necrolysis
Tx
Withdrawal agent, transfer to burn unit if severe necrolysis, manage fluid and electrolyte IVIG, Corticosteroids, antibiotics debateable
Bullous pemphigoid
Tx
Corticosteroids, Immunosuppressants (rituximab, sulfasalazine, methotrexate, IVIgG
Prone to relapse
Acne vulgaris Tx
Comedones: topical retinoid or adapalene Mild: topical abx (clinda, erythro, metro), + benzoyl peroxide, + retinoid/adapalene Moderate: See mild + PO abx (tetracyclines, erythro, clinda) Severe (nodular or cystic): isotretinoin Hormone related/excess androgens in F: add OCPs +/- spironolactone Isotretinoin AEs: depression hepatitis, increase triglycerides, premature long bone closure, highly teratogenic (-preg tests, 2 forms birth control)
Rosacea Tx
Redness: topical brimonidine (a2 agonist) Papulopustules & telangiectasias: topical metronidazole, azelaic acid, acne meds, retinoids, sulfacetamide, ivermectin cream, topical & PO abx Refractory: isotretinoin
Actinic keratosis
Tx
Cryosurgery, Curettage, Electrosurgery Topical chemotherapy (5FU)
Seborrheic keratosis
Tx
No tx -benign Cosmetic -cryotherapy
Basal cell carcinoma
Tx
Electrodessication/curettage +/- Mohs for face or recurrent Small/superficial: imiquimod and 5FU (nonfacial)
Kaposi sarcoma
Tx
HAART therapy Radiation for local
Melanoma Tx
Complete wide surgical incision +/- adjuvant therapy (a-interferon, immunotherapy, radiation) PO & topical
Thickness is most important prognostic factor for METS
Squamous cell
carcinoma
Tx
Wide local surgical excision is treatment of choice
Electrodessication and curettage, Mohs, radiation
Lice Tx
Permethrin for 10 min (head) 8-10hrs (body) 2nd line: Lindane (neurotoxic). Systemic: PO Ivermectin Wash bedding/clothing hot water and detergent and dried in hot drier
Scabies Tx
Lindane or permethrin from chin to bottom of feet overnight x7d. Tx all close contacts. Wash all clothes/bedding Antihistamines or topical steroids for itching.