Derm 1 Flashcards

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1
Q

Eczematous dermatitis

Tx

A

Acute: topical corticosteroids, antihistamines for itching. Topical calcineurin inhibitors to avoid steroids. Prevent: daily emollients, avoid irritants, phototherapy, bleach baths to avoid 2ry infxn

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2
Q

Dyshidrosis (eczema)

Tx

A

Topical steroids (ointments), cold compresses, Burrow’s solution

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3
Q

Lichen simplex Tx

A

Avoid scratching/rubbing, high strength topical steroids, antihistamines

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4
Q
Drug eruptions (fixed)
Tx
A

Drug avoidance & antihistamines

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5
Q

Lichen planus Tx

A

Most remit spontaneously in 1-2 yrs Topical corticosteroids (clobetasol, betamethasone) Intralesional injections of triamcinolone Generalized: PO steroids. Oral: paste. Phototherapy

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6
Q

Pityriasis rosea

Tx

A

Symptomatic Patient education -benign lasts 4-10wks

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7
Q

Psoriasis Tx

A

All forms: sun exposure, sea bathing, moisturizers, relax, Tar, salicylic acid lotion Determine severity→ Mild/mod <5% BSA. Severe >5% BSA Mild/Mod: Intermittent therapy-topical corticosteroids, vit D analog, tazarotene (retinoid) Continuous-Calcineurin inhib (tacrolimus) Severe: systemic tx (Methotrexate, cyclosporine, biologics (-mabs))

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8
Q

Erythema multiforme

Tx

A

Usu resolves spontaneously in 3-5 weeks Stop any drug related cause Oral antihistamine and steroids for sx’s Recurrent/prophylaxis: PO acyclovir

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9
Q

Stevens - Johnson syndrome

Tx

A

Withdrawal agent, transfer to burn unit if severe necrolysis, manage fluid and electrolyte IVIG, Corticosteroids, antibiotics debateable

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10
Q

Toxic epidermal necrolysis

Tx

A

Withdrawal agent, transfer to burn unit if severe necrolysis, manage fluid and electrolyte IVIG, Corticosteroids, antibiotics debateable

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11
Q

Bullous pemphigoid

Tx

A

Corticosteroids, Immunosuppressants (rituximab, sulfasalazine, methotrexate, IVIgG
Prone to relapse

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12
Q

Acne vulgaris Tx

A

Comedones: topical retinoid or adapalene Mild: topical abx (clinda, erythro, metro), + benzoyl peroxide, + retinoid/adapalene Moderate: See mild + PO abx (tetracyclines, erythro, clinda) Severe (nodular or cystic): isotretinoin Hormone related/excess androgens in F: add OCPs +/- spironolactone Isotretinoin AEs: depression hepatitis, increase triglycerides, premature long bone closure, highly teratogenic (-preg tests, 2 forms birth control)

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13
Q

Rosacea Tx

A

Redness: topical brimonidine (a2 agonist) Papulopustules & telangiectasias: topical metronidazole, azelaic acid, acne meds, retinoids, sulfacetamide, ivermectin cream, topical & PO abx Refractory: isotretinoin

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14
Q

Actinic keratosis

Tx

A

Cryosurgery, Curettage, Electrosurgery Topical chemotherapy (5FU)

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15
Q

Seborrheic keratosis

Tx

A

No tx -benign Cosmetic -cryotherapy

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16
Q

Basal cell carcinoma

Tx

A

Electrodessication/curettage +/- Mohs for face or recurrent Small/superficial: imiquimod and 5FU (nonfacial)

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17
Q

Kaposi sarcoma

Tx

A

HAART therapy Radiation for local

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18
Q

Melanoma Tx

A

Complete wide surgical incision +/- adjuvant therapy (a-interferon, immunotherapy, radiation) PO & topical
Thickness is most important prognostic factor for METS

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19
Q

Squamous cell
carcinoma
Tx

A

Wide local surgical excision is treatment of choice

Electrodessication and curettage, Mohs, radiation

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20
Q

Lice Tx

A

Permethrin for 10 min (head) 8-10hrs (body) 2nd line: Lindane (neurotoxic). Systemic: PO Ivermectin Wash bedding/clothing hot water and detergent and dried in hot drier

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21
Q

Scabies Tx

A

Lindane or permethrin from chin to bottom of feet overnight x7d. Tx all close contacts. Wash all clothes/bedding Antihistamines or topical steroids for itching.

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22
Q

Spider bites Tx

A

BW: Clean w/ soap and water, NSAIDs, opioid. Moderate to Severe: opiods +- muscle relaxant. Antivenom for non responsive pts if available (consult tox.) BR: Pain control (NSAIDs), tetanus, wound debridement for necrosis

23
Q

Condyloma acuminatum

Tx

A

No tx is curative, relapses are common Cryotherapy, Laser ablation, Inter-lesional interferon Drugs: Imiquimod, 5FU Vaccine prevention (9 types) Close to 100% efficacy

24
Q
Viral exanthems (Roseola)
Tx
A

Supportive, antipyretics

25
Q

Viral Exanthems (Coxsache) Tx

A

Complications: aseptic meningitis, pericarditis, myocarditis, pleurodynia Supportive -antipyretics, topical lidocaine

26
Q
Viral exanthem (Rubeola)
tx
A

Supportive: vitamin A reduces mortality Complications: diarrhea, AOM

27
Q
Viral exanthem  (5th Dz)
Tx
A

Supportive Complications: increased fetal loss in pregnancy, may cause aplastic crisis in pts w/ sickle cell dz or G6PD deficiency

28
Q

Herpes simplex

Tx

A

Acyclovir, famcyclovir, valacyclovir Higher dosing for primary, can prophylax

29
Q

Molluscum contagiosum

Tx

A

Self-limited (2 mo for single lesion) Cryotherapy NO STEROIDS

30
Q

Varicella -zoster

Tx

A

Vaccine for >60 Urgent referral for ophthalmic (Hutchinson sign) Antiviral w/in 72 hrs. Pain control

31
Q

Verrucae Tx

A

Cryotherapy

32
Q

Cellulitis Tx

A

PO: MSSA-Cephalexin, Augmentin, Dicloxacillin MRSA-Clindamycin, Bactrim, doxy, linezolid IM/IV: MSSA-Cefazolin, Nafcillin or oxacillin MRSA-Clindamycin MRSA-Vanco, daptomycin, linezolid
General: Elevate bed or extremity, warm compresses, tylenol or ibu for pain Symptomatic improvement in 24-48 hrs, visible up to 72 hrs

33
Q

Erysipelas Tx

A

PO: Penicillin Amoxicillin Cephalexin (keflex) Dicloxacillin IM/IV: Cefazolin or Ceftri General: Elevate bed or extremity, warm compresses, tylenol or ibu for pain Symptomatic improvement in 24-48 hrs, visible up to 72 hrs Tx 7-14 days

34
Q

Impetigo

A

Bactroban (Mupirocin): drug of choice If systemic,: Cephalexin (Keflex)

35
Q

Candidiasis Tx

A

Topical clotrimazole, miconazole, or nystatin PO fluconazole

36
Q

Tines Capitis Tx

A

1st line: PO Griseofulvin 2nd: PO terbinafine, itraconazole or fluconazole

37
Q

Tunes Corporis Tx

A

Topical Antifungal

38
Q

Tibet Pedis Tx

A

Topical antifungal Clean shoes w/ antifungal spray, keep feet dry

39
Q

Tinea Cruis Tx

A

Topical antifungal Avoid tight clothing, use desiccant powders

40
Q

Onychomycos is

Tx

A

48 weeks with topical meds (ciclopirox) PO: efinaconazole, terbinafine, griseofulvin, itraconazole, terbinafine (AE -hepatotoxicity)

41
Q

Pityriasis Veriscolor Tx

A

Topical (days-4wks): selenium sulfide, zinc pyrithione, azole antifungals PO: itraconazole or fluconazole Taks 2mo for rash to resolve w/ tx

42
Q

Alopecia Areata Tx

A

Intralesional corticosteroids topical steroids topical immunotherapy
Relapse common. Can resolve or progress to total hair loss.

43
Q

Male and Female pattern hair loss

A

Minoxidil increases anagrn phase, increase follicle size
Surgery
M: finasteride lowers DHT in scalp
F: spironolactone

44
Q

Paronychia Tx

A

Warm soaks I and D Abx as needed

45
Q

Acanthosis nigricans

tx

A

Treat underlying condition If no identifiable cause, look for malignancy

46
Q

Burns

A

Parkland, Debridement, Pain management, +/- Antibiotics, IV fluid (Lactated ringers)
1st: heals in 7 days, aloe/lotion 2nd: Heals in 14-21 days, may leave pigment 3rd: months 4th: does not heal well

47
Q

Hidradenitis suppurativa

Tx

A

All: punch debridement or I&D, diet, stop smoking Mild: topical clinda, intra-lesional steroid injection, +/- PO abx (doxy or minocycline) Mod: PO abx (up to 3mo), hormonal (spironolactone), Severe: prednisone, TNF-a inhibitors, PO isotretinoin Refractory: sx excision of apocrine glands

48
Q

Lipomas / Epithelial inclusion cysts

Tx

A

May surgically remove for cosmetics

49
Q

Melasma Tx

A

Hydroquinone Acid peel Retinoids

Prevention: stop OCP, Use sunscreen

50
Q

Pilondal Dz Tx

A

Sits, Antibiotics I&D

51
Q

Pressure Ulcers

A

Wet to dry dressings, hydrogels I, II- local wound care, pain management, III and IV may need surgical debridement

52
Q

Urticaria Tx

A

Wet to dry dressings, hydrogels I, II- local wound care, pain management, III and IV may need surgical debridement

53
Q

Vitiligo Tx

A

Sun protection, Cosmetics. Topical steroids Phototherapy-induced pigmentation Depigmentation 40%+ BSA involved. Skin grafting.