Depressive, Anxiety, Bipolar Disorders

Question 1

What are DA levels in depression vs mania? Serotonin? NE?

Answer 1

Decreased in depression

Increased in mania

5HT dec in depression

NE decreased in depression

Question 2

What’s one of the qualifiers for major depressive episode?

Answer 2

Depressed mood or loss of interest/pleasure

Question 3

When you hear TCAs.. specifically Trazadone, what should you think?

Answer 3

SE = priapism (inappropriate erection)

Question 4

Why is Buproprion a good drug?

Answer 4

Avoids wt gain and fatigue as SEs

Question 5

Why are MAOIs difficult to give effectively?

Answer 5

Many D/D and food restrictions

Question 6

What is Paroxetine and what SEs does it cause?

Answer 6

SSRI

Wt gain and sexual dysunction

Question 7

Benefits of Fluoxetine?

Answer 7

Longest h/l, no withdrawals!

Question 8

Withdrawals from what are either life-threatening or non-life-threatening?

Answer 8

Non: methamphetamine, heroin, cocaine
- tired and eat

LT: The B’s

• booze
• benzodiazepines
• barbituates

Question 9

Pneumonic for Depression sxs:

Answer 9

Sleep troubles
Interests lacking (anhedonia)
Guilt

Energy depleted

Concentration is poor
Appetite inc or dec
Psychomotor dec
Suicidal ideations

Question 10

Pneumonic for manic episodes:

Answer 10

Distractibility
Inflated self-esteem
Grandiosity

Flight of ideas/racing thoughts
Activity inc and Agitation
Speech-pressured
Thoughtlessness