Depression meds Flashcards
SSRI meds
(-ine, -pram), fluoxetine, citalopram, escitalopram, paroxetine, sertraline
How do SSRIs work
blocks serotonin reuptake
SSRI special stuff
SE: sexual dysfunction, neuroleptic malignant syndrome
No TCAs or MAOIs
Paroxetine = birth defects
SNRI meds
Venlafaxine, desvenlafaxine, duloxetine, levomilnacipran
How do SNRIs work
Block reuptake norepi/serotonin
levels fight/flight
SNRI special stuff
SE: neuroleptic malignant syndrome
No NSAIDS, MAOIS, anticoagulants
Atypical antidepressants
Bupropion, vilzodone, mirtazapine, trazadone ER, nefazodone
What are atypical antidepressants used for
Seasonal Affective Disorder, sexual dysfunction alternative
Atypical antidepressants special stuff
SE: insomnia, seizures
No MAOIs
TCA meds
(triptyline, pramine, pin), amitriptyline, nortriptyline, imipramine, clomipramine, amoxepine, doxepin
How do TCAs work
block reuptake of norepi/serotonin
take 10-14 days to work and 4-8wk for full effect
TCAs uses
Bipolar with depression, ADHD, OCD, insomnia, fibromyalgia, anxiety disorders
TCAs special stuff
SE: OH, dry mouth
Just dont mix it
MAOI drugs
Phenelzine, Isocarboxazid, tranylcypromine, selegine(transdermal)
How do MAOIs work
Tyramine levels