Depression & Anxiety Flashcards

1
Q

A shrubby perennial plant with bright yellow flowers

A

St. John’s Wort

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q
Which of the following is not an active ingredients of St. John's Wort?
A. Quercetin
B. Hypericin
C. Forercin 
D. Pseudohypericin
E. Hyperforin
A

C.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q
[SATA] Low levels of which of the following are linked to depression? 
A. Omega-3 Fatty Acids
B. 
C. SAM-e
D.
E. DHEA
F. Folate
A

Omega-3 Fatty Acids
SAM-e
DHEA
Folate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

vitamin B-9

A

folate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
[SATA] Which of the following is NOT a side effect of St. John's Wort?
A. depression
B. headache
C. fishy burp
D. SJS
E.  photodermatitis
A

fishy burp

SJS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are some potential drug interactions of St. John’s Wort?

A

CYP450 Inducer
Major: 3A4
Moderate: 2C9, 1A2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What happens if you take Omega 3 FAs with contraceptives?

A

decreased effectiveness of Omega 3 FAs at lowering TGs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What happens if you take Omega 3 FAs with anti-hypertensives?

A

ADDITIVE effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What happens if you take Omega 3 FAs with warfarin?

A

increased risk of bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The following side effects are related to which CAM depression agent?

women: oily skin, unwanted hair growth, deep voice, irregular periods
men: breast tenderness, aggression, testes shrink

either sex: problems with sleep, increased risk of cancer, changes in mood, cholesterol control

A

DHEA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

List 5 side effects of SAM-e

A
  • Sleep loss (mild insomnia)
  • Anxiety
  • Mouth is dry, loss of appetite, constipation, nausea
  • vErtigo (dizziness)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

List 2 side effects of folate?

A

nausea

bad taste

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

endogenous hormone, mainly made in the adrenal glands,
precursor of testosterone and estrogen,
“mother steroid”

A

DHEA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

natural compound found in most body tissues and fluid

A

SAM-e

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
Which of the following is required for synthesis of DA. NE and 5-HT? 
A. SAM-e
B. Folate
C. St. John's Wort
D. Omega-3-FAs
A

A. SAM-e

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Drug interactions with SAM-e?

A

MAJOR: seratonergic drugs —> Serotonin syndrome
Moderate: levadopa —> decreases efficacy