Depression Flashcards
Name 2 symptoms of depression
Low mood
Lack of interest in pleasure
What is an issue with diagnosis of depression?
Extraneous causal factors
Name some features of depression
1 in 6 get diagnosed aged 16 to 29
Females more likely to be diagnosed
Costs £35 billion
What does the monoamine hypothesis suggest about depression?
A group of amino acids cause symptoms.
Serotonin
Dopamine
Norepinephrine
Outline the biological reason for monoamine hypothesis
5HT gene causes deficiencies in serotonin leading to deficiencies in dopamine
How is serotonin balanced?
Blocking reuptake channels in synapse
What evidence can be given for monoamine hypothesis?
SSRI treatments help serotonin but other neurotransmitters are involved in depression
Outline the development of the monoamine hypothesis
- Serotonin,dopamine, neuropinephrine regulate mood
- Serotonin deficiency causes low mood
- Neurones increase sensitivity producing more receptors
- BDNF levels are far too low which effects Neurones chemical development
What did Sen find out in relation to monoamine hypothesis?
Negative correlation between blood BDNF levels and depressed symptoms
Postmortem found low BDNF in prefrontal cortex and hippocampus
What are the problems with Sens findings?
Correlation not causation
Difficult to establish change in BDNF levels before and after death
How long do antidepressants take to have an effect on body?
4 to 6 weeks
How long does a BDNF deficiency to be corrected
Days
How has the monoamine hypothesis developed?
Observation of antidepressants
Describe the negative triad
Negative schemas create negative views of oneself, world and future. This develops negative bias and dysfunctional views
What was the negative triad developed into?
The ABC system
What is utopianism?
Belief life should be fair
What was the sample of Evans depression study?
12003 pregnant women at 18 weeks
What were the findings of Evans depression experiment?
Women with the most negative views were most likely to develop depression even after 3 years.
Negative belief was present before depression
What was the problem with the findings from Evans depression study?
Self reported data
Correlation not causation
Postpartum depression or hormones may have been an influencing factor