Dental pathology (practicals) Flashcards
what does the periodontium comprise?
gingivae, periodontal ligament, cementum and alveolar bone
what does H&E stand for?
Haemotoxylin and eosin
used to stain biopsy material
what colour does the haemotoxylin stain and what does it stain?
acidic stuff stains blue
what colour does the eosin stain and what does it stain?
proteins stain pink
what are the 5 signs of inflammation?
redness, swelling, loss of function, pain, heat
what does plaque cause the gingiva to do?
plaque causes a loss of hemidesmosomal attachment so loss of adhesion, allowing bacteria into the anaerobic environment. elicits an immune response.
what does ulceration allow?
allows bacteria to enter the body
what is the difference between inflammation and infection?
inflammation is the body response to tissue damage
infection is the presence of pathogenic organisms in the tissue
when can you have infection without inflammation?
immuno-suppressed individuals and HIV
what are the main cells from acute inflammation and what colour do they stain?
PMNs = neutrophils (not stained much), basophils (blue), eosinophils (pink)
what do neutrophils do in the immune response?
degranulate and digest parts of tissues.
what happens when there is an accumulation of neutrophils?
pus = an accumulation of neutrophils, and therefore an abcess
what happens if an abscess is not drained?
if not drained, it becomes chronic inflammation
what cells are involved in chronic inflammation?
macrophages, plasma cells, lymphocytes
why does hyperplasia occur from plaque getting into the pockets?
inflammatory process sends signals telling cells to reproduce. oedema occurs due to leakage of capillaries.
what is ulceration?
lack of epithelium, exposure
why might a pocket look larger than it is upon probing?
depth might not look too large, but plaque causes oedema and inflammation, appearing larger
what membrane is found on both sides of the epithelial attachment of gingiva?
basement membrane
what occurs on the tooth side of the gingiva?
continued deposition of basement membrane material allows maintenance or reformation of the attachment, even in the face of disease or therapy that temporarily destroys it
what do principle collagen fibres of the PDL attach to bone cementum by?
Sharpey’s fibres