Dental care for cleft lip and palate Flashcards
What is the UK incidence of cleft lip +/- palate?
1:700 livebriths
1000 new cases per year
What are the classifications of cleft lip+/- palate?
soft palate soft and hard palate cleft lip cleft lip and alveolus cleft lip and palate
Is cleft lip +/- palate more common in girls or boys?
Boys
Is cleft palate more common in girls or boys?
girls
T/F. Cleft palate is associated with a wide range of chromosomal abnormalities? what is the percentage and wha are the syndromes?
True 15% are associated with other syndromes sticklers van der woudes pierre robin di george 22q and VCFS more than 400 syndromes
In which race is cleft lip +/- palate most common?
Indian and oriental subpopulations
Are right or left sided clefts more common?
Left
What are the two phases of palatogenesis?
- Primary palate - lip and alveolus
2. Secondary palate - hard and soft palate
At what stage in utero does palatogenesis take place?
5-12 weeks in utero
What occurs in the formation of the primary palate?
fusion of the maxillary and median nasal processes
What occurs in the formation of the secondary palate?
shelf formation
shelf elevation
shelf fusion
How do the palatal shelves fuse?
MEDIAL EDGE EPITHELIUM DEGENERATION
there is programmed cell death, cell migration and epithelial mesenchymal transformation
What are the causes of cleft lip+/- palate?
- Genetic predisposition
- associated with chromosomal abnormalities
- Teratogens
- increased paternal age
- maternal smoking/rubella
What surgical procedures are there to reduce clefts?
- Lip repair (3months): correct muscle layer, aesthtics, functionals appliance eg milliard, delaire
- Palate repair (6/9-12 months): close the palate to achieve velopharyngeal competance where ONF closed for speech
- Alveolar bone graft (8-9 years)
- Pharyngoplasty
- orthognathic surgery
- Lip adhesions
- Lip revision
- Nasal surgery
Additional problems for patients with clefts?
speech and hearing defects
up to 20% have additional abnormalities such as skeletal/cardiac/renal/CNS
Which teams look after patients with cleft lip+/- palate?
max fax ENT Speech and hearing therapists ortho dentists
What are the oral health status of cleft lip+/- palate patients?
OH is poor
poor self-cleansing
high caries prevalence
what dental complications can patients with cleft lip and palate get?
- increase in natal/neonatal teetj
- absent teeth
- supernumeraries
- anomalies in tooth morphology
- rotated teeth adjacent to the cleft
- Mobile premaxilla/ increased bilateral overbite
- cross bites
What would these mean:
- LAHSAL
- L…..
- ….al
- ..hs..
- complete bilaterial cleft lip, and palate
- right complete cleft lip
- left incompleye cleft ip and alveolus
- incomplete cleft hard and soft palate
What is the incidence for unilaterial cleft lip and palate?
25%
WHat is the incidence for billteral cleft lip and palate?
10%
WHat is CLP?
craniofacial malformation
WHat is the aetiology behind cleft lip and palate?
Genetic: complex, syndromic, non syndromic, >400 single gene causes
environmental: smoking, diet, seasonal, illness, Low SES, drugs, phenytoin, thalidomide, rubella, increased maternal and paternal age
What happens at birth for children with CLP?
contact within 24 hours specilaist nursing breast feeding rarely possible use special soft bottles sympathetic support