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Oral Histology > Dental Anomalies > Flashcards

Dental Anomalies Flashcards

1
Q

gene (codes a transcription fx) for missing maxillary PMs and mand 2nd PMs

A

Mxs1 (Mix)

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2
Q

Mxs1 codes a

A

transcription factor

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3
Q

Mxs1 mutation clinical significance

A

missing maxillary premolars and mandibular 2nd premolars

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4
Q

gene (codes transcription fx) that causes you to miss all molars

A

Pax9 (pass out)

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5
Q

Pax9 codes a…

A

transcription factor

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6
Q

I’m missing all my molars!

A

Pax9

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7
Q

Pax9 mutation clinical significance

A

missing molars

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8
Q

genes (codes signaling molecule) through Wnt pathway that causes you to be missing more than 8 permanent teeth

A

Axin2

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9
Q

Axin 2 codes a…

A

signalling molecule for the Wnt pathway

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10
Q

which pathway is the Axin 2 signaling molecule involved with?

A

Wnt pathway

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11
Q

Wnt pathway uses the _______ signalling molecul

A

Axin 2

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12
Q

a gene (codes a signaling molecule) that is involved in the TNF pathway

A

EDA

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13
Q

EDA codes for a…

A

signalling molecule for the TNF pathway

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14
Q

which gene codes for a signaling molecule involved in the TNF pathway?

A

EDA

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15
Q

Which pathways are the p63 gene’s transcription factor used in?

A

BMP, FSF, SHH

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16
Q

p62 codes a…

A

transcription factor (BMP, FGF, SHH pathways)

17
Q

Which gene mutations are related to missing teeth?

A 
Mxs1, TF
Pax9, TF
p63, TF (BMP, FGF, SHH paths)
Axin2, SM (Wnt path; colon cancer)
EDA, SM (TNF path)
18
Q

which gene codes for a signaling molecule that is related to missing more than 8 permanent teeth and risk of colon cancer?

A

Axin 2

19
Q

Which gene mutation are related to supernumerary teeth?

A

Runx2 (TF) ; cleidocranial dysplasia

Apc (SM) ; Wnt pathway ; Gardner’s Syndrome (w/ GI problems)

20
Q

Runx2 disorder

A

cleidocranial dysplasia

21
Q

Apc disorder

A

Gardner’s Syndrome

22
Q

Runx2 is a…

A

transcription factor

23
Q

Apc is a…

A

signaling molecule ; Gardner’s syndrome

24
Q

missing multiple anterior teeth

A

EDA gene mutation for the signaling molecule of the TNF pathway

25
Q

EDA mutation clinical significance

A

missing multiple anterior teeth

Oral Histology (2 decks)

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