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Neurology High Yield Part 1 > Demyelination > Flashcards

Demyelination Flashcards

1
Q

MOA of alemtuzumab

A

CD 52 macrophage inhibition

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2
Q

MOA of ocrelizumab

A

Monoclonal antibody that binds to CD 20 macrophage, resulting in B cell lysis

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3
Q

MOA of natalizumab

A

Alpha 4 beta 7 + alpha 4 beta 1 integrity antibody

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4
Q

Best predictor for prognosis of MS

A

Radiological: number of new T2 lesion over time

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5
Q

MOA dimethyl fumarate

A

Immune modulation and NrF2 pathway activation

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6
Q

MOA of fingolimod

A

Sphingosine 1 phosphate receptor modulator ( receptors 1, 3, 4, 5)

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7
Q

Teriflunamide MOA

A

Pyrimidine synthesis inhibitor

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Neurology High Yield Part 1 (6 decks)

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