Dementia

Question 1

What is the general definition of Dementia

What are the 3 groups that is involved in Dementia

Answer 1

Syndrome of brain disorders which cause memory loss + Symptoms that fall into 3 groups

1) Cognitive Impairment (memory / language / thinking)
2) Psychiatric (mood changes / personality)
3) Daily Living Changes (eating / shopping / driving)

Question 2

What % of the UK >65 have dementia

Answer 2

7%

Question 3

what is the most common cause of Dementia

Answer 3

Alzheimer’s (50%)

Question 4

In Alzheimer’s, what degeneration and atrophy occurs?

What kind of plaques also form in between neurons?

Answer 4

Cortical Atrophy

Cerebral Cortex Degeneration (thought / emotions / reasoning)

Amyloid Plaque formation

Question 5

25% of dementia is caused by …..

what type of event can this arise from

Answer 5

Vascular Dementia

Cerebrovascular event => Stroke

Question 6

Deposition of abnormal protein within neurons that accounts for 15% of dementia px

Answer 6

Dementia w/Lewy Bodies

Question 7

Specific degeneration of frontal + temporal lobes that are involved in motor function / problem solving / language / emotions is what type of dementia?

Answer 7

Frontotemporal Dementia

Question 8

When taking a history off a Dementia px, what are you looking for (4)

Answer 8

Memory

Problem Solving

Orientation

Attention

Question 9

What are 2 non-pharmalogical managements of dementia px?

Answer 9

Music / art therapy

Cognitive Stimulation Programmes

Question 10

What are the 2 groups of drugs given in Dementia px?

Answer 10

AcHE inhibitors

NMDA Antagonists

Question 11

Name 2 examples of a AcHE inhibitor given in Dementia?

Answer 11

Donepezil

Galantamine

Question 12

Name an example of a NMDA antagonist given in Dementia?

Answer 12

Memantine