Delirium, Immobility & Falls & Ageing & Frailty Flashcards
What is delirium and what are the key features of it?
Delirium=acute change in your mental state
Key features:
Disturbed consciousness-Hypoactive/hyperactive/mixed
Change in cognition- Memory/perceptual/language/illusions/hallucinations
Acute onset and fluctuant
What are other common features of delirium?
Disturbance of sleep wake cycle
Disturbed psychomotor behaviour – DELIRIUM AFFECTS YOUR PHYSICAL FUNCTION
Emotional disturbance
Does anyone really know why delirium happens?
Not really
Maladaptive pro inflam state-as get older brain is a bit leakier and as you develop cognitive frailty brain gets even leakier again – much more likely to get delirium in response to some sort of external stimuli at advances of age and frailty than you are likely to have at younger ages
What precipitates delirium?
Infection (but not always a UTI!)
Dehydration
Biochemical disturbance
Pain
Drugs
Constipation/Urinary retention
Hypoxia
Alcohol/drug withdrawal
Sleep disturbance
Brain injury-Stroke/tumour/bleed etc
Changes in environment/emotional distress
Sometimes no idea and often multiple triggers!
Antidepressants are associated with falls
Dihydrocodeine for knee pain (flare of arthritis)-well recognised side effect is constipation
Urinary retention because of constipation, already has prostate problems – bit predisposed to bladder outflow problems
How common is delirium?
Commonest complication of hospitalisation
20-30% of all in-patients
Up to 50% of people post surgery
Up to 85% of people at end of their life
Why is delirium important?
- Massive morbidity & mortality
- Increased risk of death
- Longer length of stay
- Increased rates of institutionalisation
- Persistent functional decline
How is delirium diagnosed?
4AT-Delirium Screening Tool
Everyone >65 when admitted to hosp should have one
What should be done when find delirium?
Treat the cause
- Full Hx and exam (incl. neuro)
- TIME bundle-helps to manage triggers
Explain the diagnosis!
Pharmacological measures
Non-pharmacological measures
What are the non-pharmacological treatments for delirium?
Re-orientate and reassure agitated patients- USE FAMILIES/CARERS
Encourage early mobility and self-care
Correction of sensory impairment
Normalise sleep-wake cycle
Ensure continuity of care
- Avoid hospitalisation if possible
- avoid frequent ward or room transfers
Avoid urinary catheterisation/venflons
Discharge people (if in hospital) ASAP
What pharmacological managements are appropriate for delirium?
- Drug treatment for delirium usually not necessary
- Stop bad drugs
Only if danger to themselves or others or distress which cannot be settled in any other way
Start low and go slow
12.5mg quetiapine orally
THIS SHOULD BE A CONSULTANT/REGISTRAR DECISION
Is delirium preventable?
Preventable in 30% of cases
Risk reduction for those at risk such as pain control, early mobilisation, maintaining hydration & nutrition etc
What does the delirium trajectory & follow up look like?
- Usually settles quickly with management of underlying causes
- May unmask previously undiagnosed cog impairment
- More likely to go on & develop dementia
- Risk factor for further episodes delirium/dementia/frailty syndromes so remember to record and communicate diagnosis and organise follow up
Recognise people at high risk-may influence what drugs are prescribed and what kind of community based models of care are offered to try and keep these people as fit & well and out of hospital
Is capacity decision specific?
Yes
- Legally appointed proxy decision maker can be welfare POA or guardian
Is there association between delirium & falls?
4.5x more likely to fall if have delirium
Delirium prevention interventions also reduce falls
If stop people moving-much more likely to fall – promoting mobility is very important
Why are so many UTIs overdiagnosed?
High prevalence of asymptomatic bacteriuria in older adults
Asymptomatic bacteriuria-people who if you dip their urine will have leukocytes and nitrites or will grow bug in the lab-but these people do not have an active infection.
What should not be used to diagnoses UTI in older people?
Dipstick tests
How do drugs cause falls?
DECREASE:
- BP
- HR
- Awareness
INCREASE:
- Urine output
- Sedation
- Hallucinations
- qTC
- Dizziness
What are the culprit drugs that can be responsible for falls?
Antihypertensive
Beta blocker
Sedatives
Anticholinergics
Opioids
Alcohol
- Lots of older people cure their own HT just by losing weight – frailty
How does where you are affect how you deal with a fall?
Falls clinic (full MDT)-Likely to be well patients, difficult and multifactorial falls
A+E - More likely to be acutely unwell. May not be possible to do it all
Assessing a hospital inpatient who has fallen - Very likely to be acutely unwell. Significant injury possible