Delirium Flashcards
What is delirium?
An acute and fluctuating disturbance in level of consciousness, attention and cognition, with associated behavioural changes.
How quick is the typical onset time for delirium?
Hours to days
What cognitive impairments are seen with delirium?
Worsened concentration Slow responses Confusion Disorientation Marked memory deficit
What perceptual impairments are seen with delirium?
Visual or auditory hallucinations (usually visual).
Range from distortions to hallucinations - often transient and fragmented and may not remember them by morning. Content can be related to trauma in early life.
What physical function problems are seen with delirium?
Reduced mobility Restlessness Agitation Change in appetite Sleep disturbance Speech disorders - slurring, chaotic
What social changes are seen in delirium?
Lack of cooperation with reasonable requests
Withdrawal
Altered mood
Altered personality
Do symptoms tend to be worse during day or night?
Night
Do patients with delirium have insight?
No
What are the types of delirium?
Hyperactive - restlessness, mood lability, agitation or aggression
Hypoactive - slow and withdrawn
Mixed
What are the causes of delirium?
Think delirium
Trauma (including post surgery) Hypoxia - respiratory or cardiac failure Increasing age NOF fracture SmoKer or alcohol withdrawal Drugs or drug withdrawal Environment changes - ward moves Lack of sleep Imbalances in electrolytes Retention Infections e.g pneumonia, uti, wounds, IV lines Uncontrolled pain Medical conditions e.g stroke, MI
What are some differentials?
Dementia Alcohol withdrawal Mania Post ictal Anxiety Psychosis
What drugs can cause delirium
Anticholinergics Antiemetics Antipsychotics Corticosteroids Digoxin Levodopa TCAs Opioids Alcohol
What features are diagnostic according to the CAM (confusion assessment method) tool?
Acute change in cognition which fluctuates during the day
Inattention
Disturbance of consciousness
Disorganised thinking
When diagnosing delirium what parts of the history taking process are especially important?
Collateral history - determine if changes are recent and establish normal function
Drug history including alcohol
MMSE - likely showing elicits in attention
During examination, what in particular should be looked for?
Sites of infection
Focal neurological signs - suggesting a structural CNS disorder