Degeneration DL

Question 1

Answer 1

Fatty Liver

(bad case)

-common with horses/ponies - lactation and heavily pregnant

diffuse- metabolic disease

can stain with oil red o or sudan orange/black (frozen sample)

Question 2

Answer 2

Renal Tubules (DCT) of lipodosis case

-large single vacuole

Question 3

Answer 3

Hyaline Degeneration!

• Can be caused by white muscle disease/ selenium deficiency

Question 4

Answer 4

• mucinous degeneration associated with a degenerative disease affecting the heart valves (commonly seen in dogs). Cavalier King Charles Spaniels
• Can tell it is the heart valve (endocardiosis)- don’t confuse with endocarditis
• Valves are mishapen and do not close properly
• Jet lesions
• Gross appearance: can get oedema in lungs and nutmeg liver!

Question 5

Answer 5

• nutmeg liver and pulmonary oedema caused by the cardiac issue (congestion and stasis) cause by flimsy mitral valve
• Start with LHS heart failure (oedema) and then result in RHS heart failure (nutmeg liver due to stasis of venous blood)

Question 6

Answer 6

Renal Amyloidosis

• leading to protein loss via renal failure
• transudation of low protein fluid into body cavities and tissue spaces