Definitions

Question 1

The process of tumor formation

Answer 1

Neoplasia

Question 2

“New growth” composed of cells originally derived from normal tissues that have undergone heritable genetic changes

Answer 2

Neoplasm

Question 3

Study of tumor or neoplasms

Answer 3

Oncology

Question 4

Malignant tumors of epithelial origin

Answer 4

Carcinoma

Question 5

The formation & development of collagen-rich fibrous CT stroma

Answer 5

Desmoplasia

Question 6

Reversible change in which one adult cell type is replaced by another adult cell type of the same germ line.

Answer 6

Metaplasia

Question 7

Areas within epithelia in which we have hyperplasia but also a degree of disorganization of cells and proliferation of cells

Answer 7

dysplasia

Question 8

Malignant tumor arising from skeletal muscle

Answer 8

Rhabdomyosarcoma

Question 9

Malignant tumor arising from cartilage

Answer 9

Osteosarcoma

Question 10

Malignant tumor arising from fibroblasts

Answer 10

Fibrosarcoma

Question 11

Tumors arising from multiple cell types derived from a single or multiple germ cell layers- Pluropotential or totipotential cell

Answer 11

Mixed tumors

Question 12

Benign tumor of the islet cells in pancreas

Answer 12

Insulinoma

Question 13

4 general classes of tumors

Answer 13

1. Mesenchymal tumors
2. Epithelial tumors
3. Undifferentiated tumors
4. Mixed tumors

Question 14

Tumors that arise from totipotent germ cells that contain tissues derived from all embryonic cell layers and consist of a bizarre mixture of adult and embryonic tissue types.

Answer 14

Teratomas

Question 15

Features of a benign tumor

Answer 15

1. Grow Slowly
2. Expansive growth
3. Well demarcated
4. Never metastasize
5. Well differentiated (resemble cell of origin)

Question 16

Features of a malignant tumor

Answer 16

1. Grow quickly
2. Infiltrative growth
3. borders are unclear
4. Capability to metastasize (Crab-like pattern of growth)

Question 17

Anaplasia (Cellular atypia) is characterized by:

Answer 17

1. Very large nuclei
2. Pleomorphism
3. Abnormal nuclear morphology
4. High mitotic rate
5. Loss of polarity (disorganization)

Question 18

A malignant tumor of epithelial origin that is still within the basement membrane (not invading neighboring tissue)

Answer 18

Carcinoma in situ

Question 19

A benign tumor arising from the skin

Answer 19

Papilloma

Question 20

A benign tumor arising from mucosal surface in nasal cavity

Answer 20

Nasal polyp

Question 21

Malignant tumor arising from epithelium present within lungs

Answer 21

Adenocarcinoma (From a gland)

Question 22

Tumor of the kidney present in children and pigs

Answer 22

Nephroblastoma

Question 23

Cells that do not replicate

Answer 23

Permanent cells

Question 24

Quiescent/ stable cells

Answer 24

cells that do not usually replicate but have the capacity to do so (hepatocytes)

Question 25

Cells that undergo mitotic division all the time (bone marrow, epidermis, GIT)

Answer 25

Continuously cycling/ Labile cells

Question 26

Tumor implants discontinuous with the primary tumor

Answer 26

Metastases

Question 27

Malignant tumor arising from the mammary gland

Answer 27

Mammary carcinoma

Question 28

Benign tumor of adipose tissue

Answer 28

Lipoma