Definitions Flashcards
2020 definition of pain
An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage
is pain always a personal experience?
by what is it influenced
yes
it is influenced to varying degrees by biological, psychological and social factors
Nociception
the neural process of encoding noxious stimuli
order of action of nociception
- nociceptor
- spinal cord (spinothalamic tract)
- thalamus
- somatosensory cortex
noxious stimulus
a stimulus that is damaging or threatens damage to normal tissues
does nociception equal pain?
no
nociception is neither sufficient nor necessary for pain
T/F: nociception is the output of the brain
false
pain is the output
nociception -> modulation -> pain
chronic pain
mainly characterized as pain that has persisted for more than 3 months, with the implication that typical tissue healing time has passed
BPS perspective 1 is
causation (multifactorial) perspective
BPS perspective 2 is
humanistic (person-centered) perspective
Peripheral sensitization
- increased responsiveness of nociceptors to stimulation of their respective fields
- increased size of nociceptors’ fields
- reduced threshold of nociceptors to stimulation of their receptive fields
- activation of silent nociceptors
where is the pain modulated?
PNS and CNS
in other words, central sensitization is an
amplification of neural signaling within the CNS that elicits pain hypersensitivity
central sensitization
- increased responsiveness of nociceptive neurons in the CNS to their normal or subthreshold afferent input
- increased size of receptive fields for nociceptive spinal dorsal horn neurons
- reduced threshold of nociceptive spinal dorsal horn neurons to stimulation of their receptive fields
- temporal summation of pain = progressively increasing pain to the same stiimulus administered repetitively or over a long duration
hypoalgesia
diminished pain in response to a normally painful stimulus
hyperalgesia
increased pain from a stimulus that normally provokes pain
allodynia
pain due to a stimulus that does not normally provoke pain
pain threshold
the minimum intensity of a stimulus that is perceived as painful
evoked pain intensity
the intensity of pain evoked by a stimulus, measured numerically from 0-10
temporal summation
progressively increasing activity of the dorsal horn neurons in response to repetitive or sustained noxious stimuli