Definition of Pharmacology

Question 1

Elimination Half - Life (T1/2)

Answer 1

The time it takes for 50% of a particular drug to be cleared from the blood stream

Question 2

Routes of Elimination

Answer 2

Kidney, Lung or Bowel

Question 3

Anatomical Barriers to Distribution

Answer 3

Blood - Brain Barrier
Placental Barrier

Question 4

Pharmacokinetic Phase (ADME)

Answer 4

Absorption
Distribution
Metabolism
Elimination

Question 5

Duration of Action

Answer 5

The time between the onset of action and the discontinuation of drug action

Question 6

Peak Effect

Answer 6

The maximum effect produced by a drug after it has reached its maximum concentration in the body.

Question 7

Onset of Action

Answer 7

The time it takes for a drug to produce a therapeutic effect

Question 8

Food and Drug Amendments Act (2007)

Answer 8

Set guidelines for post market clinical studies

Question 9

Comprehensive Drug Abuse Prevention and Control Act (1970)

Answer 9

Places controlled substances into categories C-1 through C-V, regulating drugs with a history of abuse

Question 10

Pharmaceutical Equivalent

Answer 10

Different inactive ingredients, dosage form, and exhibits different absorption rates than brand name product

Question 10

Kefauver-Harris Amendment (1962)

Answer 10

Requires drugs to be safe and effective

Question 10

Durham- Humphrey Amendment (1950)

Answer 10

Categorized drugs as either legend (prescription only) or over -the -counter (no prescription required

Question 11

Whey are drugs used

Answer 11

Diagnosis
Treatment
Mitigation of Symptoms
Cure Disease
Prevent Disease

Question 11

Routes of Administration

Answer 11

Oral
Topical
Inhalation
Parenteral

Question 11

Pure Food and Drug Act (1906)

Answer 11

sets the standards for allowing new drugs onto the market

Question 11

Therapeutic Alternative

Answer 11

Different active ingredients, yet produce the same desired therapeutic outcome

Question 12

First Pass Effect

Answer 12

A process in which the liver metabolizes nearly all of a drug to an inactive metabolite before the drug passes into the general circulation.

Question 12

Pharmaceutical Alternative

Answer 12

Same active ingredient as the brand name, strength and dosage form may be different

Question 13

Bioequivalence

Answer 13

No statistical differences are found in the rate and extent of absorption between the generic product and the brand name product.

Question 14

Bioavailability

Answer 14

The extent to which an administered amount of drug reaches the site of action and is available to produce the desired drug effects.

Question 15

Generic Drug Basics

Answer 15

contains the same active ingredients as the brand name drug

May be offered b the generic manufacturer after the patient period of the brand drug ends

Can receive an A rating from the FDA if not significantly different from the original drug

Question 16

Why is knowledge of pharmacology important for technicians

Answer 16

Help reduce dispensing errors

Improves recognition of possible problems with drug orders, such as drug interactions and therapeutic duplications