Definicion

Question 1

Def

Answer 1

is a life-threatening disorder that can result from primary adrenal failure or secondary adrenal disease due to impairment of the hypothalamic– pituitary axis
It is the clinical manifestation of defi cient production or action of glucocorticoids, with or without defi ciency also in mineralocorticoids and adrenal androgens

Question 2

Primary adrenal insuffi ciency

Answer 2

results from disease intrinsic to the adrenal cortex

Question 3

Secondary adrenal insufficiency

Answer 3

results from pituitary disease that hampers the release of corticotropin or from a lack of responsiveness of the adrenal glands to this hormone.

Question 4

Tertiary adrenal insufficiency

Answer 4

results from the impaired synthesis or action of corticotropin-releasing hormone, arginine vasopressin, or both, from the hypothalamus, which in turn inhibits secretion of corticotropin