define

Question 0

Aseptic

Answer 0

free of microorganisms

Question 1

admixture

Answer 1

The product that results from adding a drug to a parenteral solution for administration to a patient

Question 2

aseptic technique

Answer 2

procedures conducted under controlled situations to minimize the chance of contamination. The ability of personnel to manipulate sterile preparations, sterile packaging components, and sterile administration of devices in a way that excludes the introduction of viable microorganisms.

Question 3

batch preparation

Answer 3

compounding of multiple units of the same item (e.g. of the same strength or volume).
not for immediate use

Question 4

Biological Safety Cabinet (BSC)

Answer 4

A ventilated cabinet (with stainless steel surfaces) with inward airflow for personnel protection, high-efficiency particulate air (HEPA)-filtered laminar airflow for product protection, and HEPA-filtered exhausted air for environmental protection.

Question 5

carcinogenic

Answer 5

tending to cause the development of cancer

Question 6

chemotherapy

Answer 6

The treatment of disease by chemical means. Commonly used to describe drug (chemical) therapy for cancer.

Question 7

class 100 environment

Answer 7

describes the level of cleanliness for environments that have concentrations of less than 100 particles (0.5 micron and larger) per cubic foot.

Question 8

compounding

Answer 8

The process of preparing parenteral admixtures

Question 9

contamination

Answer 9

The presence of microbial or particulate matter where it is not desired, particularly where it’s presence may be harmful.

Question 10

critical area

Answer 10

an area intended to protect sterile product during manipulation from any secondary microbial contamination. The laminar airflow hood or biological safety cabinet located within the aseptic preparation area.

Question 11

critical site

Answer 11

The point at which a sterile product or sterile packaging materials may come in contact with contamination (e.g. the point of attachment of a needle to a syringe).

Question 12

decontamination

Answer 12

destruction, neutralization or removal of a toxic agent.

Question 13

diluent

Answer 13

for diluting, an agent that dilutes or renders less potent. often used to describe a liquid that is added to a mixture

Question 14

disinfection

Answer 14

The act of removing infection (i.e. eliminating potentially infectious material from in animate objects).

Question 15

evacuated bottle

Answer 15

an empty glass bottle in which a vacuum has been created by withdrawing its contents. A negative pressure exists within the bottle which may be used to advantage in filtration procedures or when combining solutions into one container.

Question 16

exposure

Answer 16

The condition of being subjected to something, such as to infectious agents or chemicals, that may have a harmful effect. Acute exposure is of short duration; chronic exposure is long-term, either continuous or intermittent.

Question 17

handling

Answer 17

manipulations which may bring the operator into contact with the product (e.g. preparation, compounding, administration, disposal).

Question 18

hazardous

Answer 18

dangerous, risky, representing a health risk (e.g. chemicals that may be corrosive, flamable, cytotoxic).

Question 19

HEPA filter

Answer 19

A high-efficiency particulate air filter that has the capability of retaining particles as small as 0.3 µm with a minimum efficiency of 99.9%

Question 20

in vitro

Answer 20

within a glass; observable in a test tube; in an artificial environment.

Question 21

incompatibility

Answer 21

not suitable for combination. with respect to admixture preparation, usually refers to phenomena such as precipitation, turbidity, colour change or a non-visible chemical alteration of the product.

Question 22

laminar airflow hood

Answer 22

A ventilated cabinet (with stainless steel surfaces) which provides a linear pattern of airflow from a high-efficiency filter to create a suitable environment for preparation of sterile parenteral admixtures. The direction of flow pattern of the laminar airflow hood can be horizontal or vertical.

Question 23

luer-lock

Answer 23

I threaded attachment (fitting) commits connection by twisting one component into another. Such connections are secure (e.g. A syringe may have a luer-lock tip which excepts a needle by a twisting motion).

Question 24

overwrap

Answer 24

outer covering which protects the package contents

Question 25

parenteral

Answer 25

injection beneath the skin surface. early means other than intestinal

Question 26

patency

Answer 26

The condition of being wide open

Question 27

peritoneum

Answer 27

A strong membrane with a smooth surface, it forms a sack closing the abdominopelvic contents.

Question 28

polyamp

Answer 28

A term to describe a plastic ampoule

Question 29

sterile

Answer 29

free of living microorganisms

Question 30

support area

Answer 30

A room adjacent to the aseptic preparation area activities related to sterile product compounding are performed. activities may include: handwashing, gowning, gloving, gathering of materials, sorting finished products for delivery to patient care areas.