deficiencies

Question 1

cheilosis and corneal vascularization

Answer 1

riboflavin/B2

Question 2

peripheral neuropathy, esp. while taking isoniazid

Answer 2

pyridoxine/B6

Question 3

sideroblastic anemia: what causes it?

Answer 3

pyridoxin/B6

impaired heme synthesis

Question 4

adrenal insufficiency, hair loss, rash

Answer 4

panthothenic acid/B5

Question 5

dark/pigmented spots on sclera, trouble seeing at night, loss of eyesight

Answer 5

A

Question 6

dry, scaly skin

Answer 6

A

Question 7

iron deficiency anemia and immunosuppression

Answer 7

C

Question 8

scurvy , why?

Answer 8

C

necessary for hydroxylation of lysine/proline on collagen

Question 9

hemolytic anemia (why?) and loss of proprioception and epicritic sensation (why?)

Answer 9

E
protects RBC’s/membranes from free radicals
demyelination of dorsal column and spinocerebellar tract

Question 10

swollen tongue

Answer 10

B3/niacin

Question 11

difference b/w megaloblastic anemia due to B9/B12?

Answer 11

B12: elevated MMA and homocysteine, paresthesia/ataxia/loss fine touch
B9: only elevated homocysteine

Question 12

confusion, paralysis of eye muscles, ataxia

Answer 12

thiamine/B1-Wernicke

Question 13

making things up, personality change, memory loss

Answer 13

thiamine/B1-Korsakoff

Question 14

what disease shows niacin deficiency? why?

Answer 14

Hartnup: tryptophan deficiency

Question 15

similarity/difference b/w B12 and E deficiency

Answer 15

same: degeneration of dorsal column/spinocerebellar tract
B12: megaloblastic anemia, also corticospinal
B9: hemolytic anemia

Question 16

what causes pellagra? describe it

Answer 16

niacin/B3 deficiency

diarrhea, hallucinations, dementia, hyperpigmentation esp. around collar

Question 17

what drugs can cause folate deficiency?

Answer 17

phenytoin, sulfonamides, methotrexate

Question 18

paresthesias/peripheral neuropathy

may have muscle wasting

Answer 18

dry beri beri: thiamine/B1

Question 19

peripheral neuropathy, heart failure, pulsations and edema, large heart

Answer 19

wet beri beri: thiamine/B1

Question 20

what vitamin needs to be given to neonates to prevent neonatal hemorrhage?

Answer 20

vitamin K