Deck 2 - Autonomic Nervous System drugs

Question 1

what is the meaning of ANS?

Answer 1

Autonomic nervous system

Question 1

What are the two types of ANS?

Answer 1

Sympathetic. Parasympathetic.

Question 2

Please provide a list of the effects of Alpha 1 Adrenergic receptors.

Answer 2

Eye - pupil dilation
Blood vessels - vasoconstriction (increased BP)
Bladder - bladder relaxes
Prostate- Contraction

Question 3

Give 2 List of effects of Alpha 2 Adrenergic receptors.

Answer 3

Blood vessels-Decreased blood bressure
Smooth muscle- Decreased gastrointestinal tone and motility

Question 4

Please provide two lists of the effects of Beta 1 Adrenergic receptors.

Answer 4

Heart - increased heart rate to pump more blood, increased conduction through AV node, increased force of contraction
Kidney - secretes renin to retain water

Question 4

Please provide lists of the effects of Beta 2 Adrenergic receptors.

Answer 4

Smooth muscle
Lungs
Uterus
Liver

Question 5

What are the other names for Adrenergic drugs?

Answer 5

Adrenergic agonists & Sympathomimetics

Question 6

What are 5 known as adrenergic agonists drugs?

Answer 6

Epinephrine
Isoproterenol
Dobutamine
Pseudoephedrine or phenylephrine
Albuterol

Question 7

What are 8 known as adrenergic antagonists drugs?

Answer 7

Phentolamine or phenoxybenzamine
Prazosin, Terazosin
Tamsulosin, Alfuzasin
Propanolol (1st gen)
Timolol (1st gen)
Atenolol, Metoprolol
Carvedilol, Labetalo
Pindolol

Question 8

Direct-acting sympathomimetic vs. Indirect acting sympathomimetic

Answer 8

Direct-acting = binds directly onto the specific receptor to cause a response
Indirect-acting = stimulates the presynaptic neuron to release neurotransmitters, which then bind to the specific receptor to cause a response

Question 9

What are the 2 main adrenergic receptors?

Answer 9

alpha-1 and alpha-2

Question 10

What are the classification of adrenergic blocking drugs?

Answer 10

nonselective, selective, and β blockers

Question 11

two main classes cholinergic drugs

Answer 11

1. Cholinergic agonist (enhance) action acetylcholine.
2. Anticholinesterase drugs inhibit destruction of acetylcholine.

Question 12

How many types of adrenergic receptors are there?

Answer 12

three types: alpha-1, alpha-2, and beta

Question 13

what is Cholinergic Drugs action?

Answer 13

promote action of neurotransmitter Acetylcholine (imitates parasympathetic)

Question 14

What are the types of ACh receptors?

Answer 14

• Nicotinic ACh receptors
• Muscarinic ACh receptors

Question 15

What are the direct cholinomimetic agonists?

Answer 15

• Bethanechol
• Carbachol
• Pilocarpine
• Methacholine

Question 16

What does cholinesterase inhibitor poisoning cause (DUMBBELS)?

Answer 16

DUMBBELS:
- Diarrhea
- Urination
- Miosis
- Bronchospasm
- Bradycardia
- Emesis
- Lacrimation
- Sweating/Salivation

Question 17

what are the 4 direct acting ink cholinergic agonists drug?

Answer 17

Acetylcholine,Carbachol,
Pilocarpine,Bethanechol

Question 18

what are the 4 indirect acting reversible cholinergic agonists drug?

Answer 18

edrophonium,physostigmine
neostigmine, pyridostigmine,rivastigmine, donepezil, galantamine