DDx Dysphagia Flashcards

1
Q

What are the four phases of Dysphagia?

A
  • Abnormal Oral phases = abnormal prehension, mastication, lubrication, and transportation of food from tongue to pharynx
  • Abnormal Pharyngeal phase= food bolus doesn’t propel from oropharynx, though hypopharynx, and to proximal esophagus.
  • Cricopharyngeal dysphagia is abnormal transportation of bolus through proximal esophageal sphincter. This is due t inadequate or complete lack of opening/relaxation (cricopharyngeal achalasia) of upper esophageal sphincter or from abnormal riming of its opening/relaxation (cricopharyngeal asynchrony)
  • Esophageal dysphagea is difficuly in passing bolus down the esophageal body
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2
Q

WHat are the clinical signs of oral, pharyngeal, and oesophageal dysphagia?

A
  • Oral dysphagia = Difficulty prehending or masticating food, and unable to transport to base of tongue
  • Pharyngeal dysphagia = gagging or retching, repeated attempts to swallow, excessive head movements, and dropping food from mouth.
  • esophageal dysphagia = regurgitation
  • Note coughing can occur with any form of dysphagia
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3
Q

What are common signlaments of dysphagia?

A
  • Cricopharyngeal achlasia is congenital and likely observed in juvenile dogs at weaning
  • Heritable trait for oropharyngeal dysphagia in Golden retrievers
  • Foreign body most likely in young-midle aged pets
  • Geriatric pets are most likely going to have systemic disease
  • Cats less likely to have dysphagia but it is usually secondary to oral tumour, ulcer, or stomatitis
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4
Q

What are the obstructive lesion differentials causing dysphagia?

A

Cause of dysphagia

Diagnosis

Survey radiographs of head, neck, thorax, CBC< biochem (CK+electrolytes), urinalysis

Obstructive lesions (mechanical or anatomic)

Foreign body

Oral and laryngeal exam under anaesthesia to identify obstructions

Endoscopy+/- fluoroscopy may be required

Neoplasia

Inflammatory (absess, polyp, granuloma)

lymphadedonopathy

Sialocele

Lingual frenulum disorder

Cleft palate

TMJ disorder

Trauma (fracture, luxation)

Cricopharyngeal achalasia/asynchrony

Absent gag reflex

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5
Q

What are the pain differentials causing dysphagia?

A

Pain

Periodontal (tooth fracture/abscess, periodontitis)

Oral and laryngeal exam under anaesthesia to identify inflammatory processes

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6
Q

what are the neuromuscular differentials causing dysphagia?

A

Neuromuscular disorders

Inflammatory myopathy (masticatory myositis, polymyositis)

Neurological exam +/- exam under anaesthesia to identify laryngeal paralysis

Polyradiculitis

Botulism

Tick paralysis

TMJ disease

Myasthenia gravis

Acetylcholine receptor antibody titer

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7
Q

What endocrine disorder can cause dysphagia?

A

Hypothyroidism

Thyroid testing

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8
Q

What treatment options are available for dysphagia?

A
  • Accurate diagnosis is required
  • If untreatable change food consistency (liquid, solid), meal frequency (smaller, more frequent), and feed positions (upright) could be attempted.
  • If adequate calories not provided then place a feeding tube.
  • Treat complications such as aspiration pneumonia
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9
Q

What is the definition of regurgitation?

A

= Passive expulsion of food or fluid from esophagus due to mechanical, obstructive disease or functional (motility) abnormalities.

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10
Q

What are the clinical signs of regurgitation?

A
  • May notice pets head lowers and produces maerial or find fluid or food without hearing the pet.
  • Can be immediately or hours after feeding, and can vary from digested or undigested food, mucous or clear, frothy liquid.
  • Bilous material is not associated with regurgitation. Odynophagia and ptyalisms may be present
  • Systemic signs – weight loss, polyphagia, weakenss, and other neurologic abnormalities.
  • Aspiration pneumonia may be present
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11
Q

What are the common signalments of regurgitation?

A
  • Megaesophagus
  • Congenital megaesophagus: Labrador retrievers, newfoundlands, Chinese Shar-peis
  • +/- acquired: Great Dane, German Shepherd and Irish setter
  • Clinical and non-clinical motility disorder that may improve ore resolve with maturation in Shar-Peis, Bouviers des Flandres and terrier breeds
  • Spirocercosis may cause esophageal dysphagia
  • Recent anaesthetic epidosed (e.g. spay/neuter, dentistry) and oral medication (doxycycline, clindamycin) are common cause of esophageal structure
  • Anaesthesia can cause megaesophagus from esophageal muscle atony secondary to gastroesophageal reflux- induced esophagitis.
  • Idiopathic laryngeal paralysis associated with esophageal dysfunction
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12
Q

What are the esophageal disorfer differentials causing regurgitation? And their associated diagnostic tests?

A

Esophageal Disorders

Megaesophagus (primary/secondary)

Plan cervical and thoracic radiographs:

Esophageal dilation

Focal with stricture or vascular ring anomaly, generalised with megaoesophagus

Foreign body, mass

Radiopaque structures

Thymoma

Widening of mediastinum

Esophagitis

If plain radiographs non diagnostic then esophagram, endoscopic exam, or videofluorscopic exam

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13
Q

What are the alimentary disorders that can cause regurgitation?

A

Pyloric outlflow obstruction

Hiatal hernia

Gastric dilatation volvulus

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14
Q

What neurological disoders can result in regurgitation?

A

CNS (brainstem lesion, neoplastic, trauma)

Peripheral neuropathy (lead, thallium, polyradiculitis, polyneuritis)

Dysautonomia

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15
Q

What neuromuscualr disorders can reslt in regurgitation?

A

Botulism

Tetanus

Distemper

Acetylcholinsterase toxicity

Myasthenia gravis

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16
Q

What are the infectious causes that can cause regurgitation?

A

Spirocercosis

Pythium insidiosum

Neosporosis

17
Q

If radiographs are non diagnostic for regurgitation what would be your next steps?

A

If radiographs are non diagnostic –>

  • CBC,
  • biochem
  • urinalysys
  • T4 – complete thyroid profile
  • faecal analysis
  • lead level assay
  • ACTH stim test
18
Q

ways to help food move down oesophagus

List treatment and management options for regurgitation….

A
  • Dietary and feeding modifications such as small, frequent high-calorie meals
  • Keep upright during and after feeding (e.g. Bailey Chair)
  • Coupage to help food move down eophagus
  • Gastrostomy feeding tube plavement to achieve adequate caloric intake and reduce regurgitation episodes
  • Prokinets drugs are likely ineffective on striated esophageal muscle, and could make it harder for food to pass due to enhancing lower esophageal sphincter pressure
  • Bethanechol may be effective in dogs
  • Cats may find cisapride effective due to cholinergiv neurons of esophagus
  • Gastroprotective therapy to decrease stomach acid (proton pump inhibitors, H2-recepto antagonists) and mucosal protectants (sucralfate) instituted, and prokinetic agents to increase lower esophageal sphincter tone in cases of primary esophagitis
19
Q
A