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drug-drug interaction > ddi > Flashcards

ddi Flashcards

1
Q

acetaminophen

A

warfarin

increased INR
risk for bleeding

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2
Q

amiodarone

A

digoxin

digoxin toxicity

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3
Q

amiodarone

A

satins

rhabdomyolysis

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4
Q

ACEI and ARB

A

co-trimoxazole (TMP/SMX)

hyperkalemia

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5
Q

antihypertensive (diuretics, acei, arb)

A

NSAID

hypertension
risk for acute renal failure

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6
Q

benzodiazepines

A

opioids

comatose

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7
Q

clonidine

A

propranolol

rebound hypertension

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8
Q

nitrates

A

sildenafil

sudden drop in blood pressure

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9
Q

nitrates

A

sildenafil

sudden drop in blood pressure

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10
Q

potassium chloride

A

spironolactone

hyperkalemia

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11
Q

potassium chloride

A

spironolactone

hyperkalemia

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12
Q

PPI

A

thyroid supplementation

hyperthyroidism

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13
Q

tramadol

A

SSRI & serotononin/norepinephrine reuptake inhibitor

serotonin syndrome (mental status change, neuromuscular hyperactivity, autonomic hyperactivity)

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14
Q

CCB

amlodipine
felodipine

A

Clarithromycin

hypotension
acute renal failure

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15
Q

Verapamil

A

Colchicine

breakdown of muscle tissue
loss of red and white blood cell
multiple organ failure

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16
Q

Verapamil

A

Digoxin

bradycardia
possible heart block

drug-drug interaction (1 decks)

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