DD - Anti-Infective Agents - Basics Flashcards

1
Q

Penicillins

A

Mechanism of action: Cell wall synthesis inhibitors

Penicillin G, Pencillin V

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2
Q

Extended-spectrum penicillins

A

Mechanism of action: Cell wall synthesis inhibitors

Amoxicilin, Ampicillin

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3
Q

Antipseudomonal penicillins

A

Mechanism of action: Cell wall synthesis inhibitors

Piperacillin

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4
Q

Penicillin plus beta-lactamase inhibitor

A

Mechanism of action: Cell wall synthesis inhibitors

Amoxicillin-Clavulanate, Piperacillin-Tazobactam

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5
Q

1st Generation Cephalosporins

A

Mechanism of action: Cell wall synthesis inhibitors

Cephalexin, Cefazolin

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6
Q

2nd Generation Cephalosporins

A

Mechanism of action: Cell wall synthesis inhibitors

Cefuroxime

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7
Q

3rd Generation Cephalosporins

A

Mechanism of action: Cell wall synthesis inhibitors

Ceftriaxone

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8
Q

Other cell wall synthesis inhibitors

A

Vancomycin

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9
Q

Tetracyclines

A

Mechanism of action: Protein synthesis inhibitors

Tetracycline, Doxycycline

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10
Q

Macrolides

A

Mechanism of action: Protein synthesis inhibitors

Erythromycin, Azithromycin, Clarithromycin

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11
Q

Lincomycins

A

Mechanism of action: Protein synthesis inhibitors

Clindamycin

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12
Q

Synthetic Agents

A

Mechanism of action: Protein synthesis inhibitors

Chloramphenicol

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13
Q

Quinolones & Floroquinolones

A

Mechanism of action: Inhibition of DNA function

Levofloxacin

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14
Q

Other inhibitors of DNA function

A

Metronidazole

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15
Q

Zanamivir, Oseltamivir

A

Neuraminidase inhibitors, against influenza

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16
Q

Rimantadine

A

Block of M2 proton channel, against influenza

17
Q

Acyclovir, Valacyclovir

A

Inhibitor of viral DNA polymerase, against herpes (simplex / varicella / zoster)

18
Q

Amphotericin B

A

Anti-fungal agent; cell membrane disruption

19
Q

Fluconazole, Itraconazole, Ketoconazole, Clotrimazole

A

Anti-fungal agent; ergosterol synthesis inhibitor (inhibition of cell wall/cell membrane component synthesis)

20
Q

Terbinafine

A

Anti-fungal agent; squalene synthesis inhibitor (inhibition of cell wall/cell membrane component synthesis)

21
Q

Penicillinase-resistant penicillins

A

Mechanism of action: Cell wall synthesis inhibitors

Dicloxacillin