DD - Anti-Infective Agents - Basics Flashcards
Penicillins
Mechanism of action: Cell wall synthesis inhibitors
Penicillin G, Pencillin V
Extended-spectrum penicillins
Mechanism of action: Cell wall synthesis inhibitors
Amoxicilin, Ampicillin
Antipseudomonal penicillins
Mechanism of action: Cell wall synthesis inhibitors
Piperacillin
Penicillin plus beta-lactamase inhibitor
Mechanism of action: Cell wall synthesis inhibitors
Amoxicillin-Clavulanate, Piperacillin-Tazobactam
1st Generation Cephalosporins
Mechanism of action: Cell wall synthesis inhibitors
Cephalexin, Cefazolin
2nd Generation Cephalosporins
Mechanism of action: Cell wall synthesis inhibitors
Cefuroxime
3rd Generation Cephalosporins
Mechanism of action: Cell wall synthesis inhibitors
Ceftriaxone
Other cell wall synthesis inhibitors
Vancomycin
Tetracyclines
Mechanism of action: Protein synthesis inhibitors
Tetracycline, Doxycycline
Macrolides
Mechanism of action: Protein synthesis inhibitors
Erythromycin, Azithromycin, Clarithromycin
Lincomycins
Mechanism of action: Protein synthesis inhibitors
Clindamycin
Synthetic Agents
Mechanism of action: Protein synthesis inhibitors
Chloramphenicol
Quinolones & Floroquinolones
Mechanism of action: Inhibition of DNA function
Levofloxacin
Other inhibitors of DNA function
Metronidazole
Zanamivir, Oseltamivir
Neuraminidase inhibitors, against influenza
Rimantadine
Block of M2 proton channel, against influenza
Acyclovir, Valacyclovir
Inhibitor of viral DNA polymerase, against herpes (simplex / varicella / zoster)
Amphotericin B
Anti-fungal agent; cell membrane disruption
Fluconazole, Itraconazole, Ketoconazole, Clotrimazole
Anti-fungal agent; ergosterol synthesis inhibitor (inhibition of cell wall/cell membrane component synthesis)
Terbinafine
Anti-fungal agent; squalene synthesis inhibitor (inhibition of cell wall/cell membrane component synthesis)
Penicillinase-resistant penicillins
Mechanism of action: Cell wall synthesis inhibitors
Dicloxacillin