Day 7 Transplant

Question 1

What is the difference between an autogeneic transplant and and allogeneic transplant?

What are the 3 ways to get stem cells?

How can you mobilize stem cells?

Answer 1

Auto–> Self cells, Allo–> Other cells(may also have anti tumor effects).

Bone Marrow, Peripheral Blood Stem Cells, Umbilical Cord.

Chemotherapy,Hematopoeitic growth factors.

Question 2

In time to engraftment is peripheral blood faster or slower than bone marrow?

Does blood have higher or lower risk for GVHD than bone marrow?

Does peripheral blood have increased or decreased risk for graft failure than bone marrow?

Answer 2

Faster.

Higher risk.

Decreased risk.

Question 3

What is the overall 5 year survival of pediatric cancer patients?

What are presenting symptoms of child leukemia?

What are some late effects a child can have from chemotherapy?

Answer 3

> 80%.

Low red blood cells(fatigue, weakness, light headed, headaches, pale skin, feeling cold). Low white(frequent infections, fever). Low platelets( easily bruises, frequent nose or gum bleeds).

growth and development, organ function, fertility, secondary cancers, psychosocial issues. This can be dependent on type, age, and treatment.