Day 7- Introduction to Women's health Flashcards

1
Q

Which structure produces estrogens?

Which cell has FSH receptors and LH receptors and which one has only LH?

When does ovulation occur and which phase shows a predominance of FSH vs LSH?

A

Anterior pituitary, FSH, and Granulous cells(directly) of the ovarian follicles.

Granulosa has both while thecal has only LH.

Day 14, Follicular has high FSH, LH is luteal phase

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2
Q

What happens to the corpus luteum and hormones if pregnancy occurs?

What does aromatase do?

What are your cervical cancer screening recommendations?

A

Corpus lutuem enlarges and persists with progesterone, estrogen and relaxin production, which help maintain the pregnancy.

Cholesterol gets turned into estradiol via aromatase.

Age 21-65 get a screening with cytology at least once every 3 years.

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3
Q

What is primary vs secondary amenorrhea?

What could cause amenorrhea?

Are psychological/affective symptoms more indicative of PMS or PMDD?

A

Primary is absence of menses in women who never developed a menstrual period by the age of 16 years. Secondary is absence of menses for more than 3 months.

Anorexia or excessive exercise, hyperprolactinemia, Anovulation secondary to PCOS, other/unknown.

PMDD. Symptoms improve in PMS with ovular suppression.

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4
Q

What is primigravida vs nulligravida?

What is parity?

How does blood pressure change in pregnancy?

A

Primi is first pregnancy and nulli is never been pregnant or conceived.

number of deliveries beyond 20 weeks gestation, nulliparious is never having given birth.

Decreased at first due to vasodilation, Gradual increase in BP around 28 weeks.

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5
Q

How does a change in DME affect drug pharmacodynamics and kinetics in pregnancy?

What should people know about pregnancy tests?

What are the indirect causes of maternal mortality?

A

Because of increased glomerular filtration, clearance of drugs which are renally cleared may increase. As pregnancy progresses, serum concentrations of creatinine decrease.

Do in 1st void of the day. Less accurate for the detection of pregnancy after the 10th week due to dropping plasma and urine concentrations.

Asthma, Heart disease, type 1 diabetes, and SLE.

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6
Q

How much calcium should women older than 19 consume?

What is pharmacological treatment for management of N/V in pregnancy?

When should you avoid NSAIDS?

A

1,000 mg.

Pyridoxine/doxylamine, dimenhydrinate or diphenhydramine, metoclopramide or ondansetron.

Not in last trimester!

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7
Q

What do you use to treat Pelvic Inflammatory Disease?

What is the big thing to watch for with preeclampsia?

What are your options in htn and preeclampsia treatment?

A

IV Clindamycin.

Visual disturbances, develops after the 20th week and is accompanied by other stuff. It’s bad because preterm birth risk is increased by 5 fold.

Labetalol, Nifedipine, Methyldopa, Thiazide diuretics are second line.

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8
Q

When does GDM usually occur in pregnancy?

What are your treatment options for GDM?

When is your sensitive time for the fetus?

A

Between 24 and 28 weeks.

Metformin, glyburide, insulin.

Weeks 3-5 when the heart, neural tubes, and limbs form.

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9
Q

What is the best depression treatment in pregnancy?

When does ovulation occur and what hormone is predominant before then and after then?

How do granulosa cells increase progesterone and how do thecal cells make testosterone?

A

Sertraline.

Day 14, Estrogen before and Progesterone after due to surge of LH.

Ganulosa cells increase progesterone via LH and thecal cells make testosterone from cholesterol.

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10
Q

Does the luteal phase have a surge of LH?

What should folic acid and iron be dosed at for pregnant women?

Is diarrhea or constipation more common during pregnancy and what does aromatase do?

A

YES.

Folic acid is 400 mcg daily and iron should be 45 mg per day.

Diarrhea, Aromtase makes estradiol

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11
Q

What gland releases FSH and LH and which one releases GnRH?

A

FSH, LH–> Anterior Pituitary and GnRH is the hypothalamus.

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