Day 5 Genes

Question 1

Trem1

Answer 1

Triggering receptor belonging to Ig superfamily

Question 2

Ccr7

Answer 2

activates B-cell function in chronic inflammation

Question 3

Cd81

Answer 3

B-cell receptor signaling pathway (CD19 complex) of NFkB pathway

Question 4

Cd38

Answer 4

cell adhesion, signal transduction

Question 5

Gna13

Answer 5

modulators/transducers in transmembrane signaling systems

Question 6

Nfkb1

Answer 6

Pro-inflammatory chemokines, cytokines, adhesion molecules, proliferation, survival, Ig Class switching

Question 7

Bax

Answer 7

anti-/pro-apoptotic regulator **asthma shown to highly downregulate this gene

Question 8

Btk

Answer 8

B-cell development, mast cell activation w/ high-affinity IgE receptor

Question 9

Lgals

Answer 9

Regulating apoptosis, cell proliferation/differentiation

Question 10

Irak1

Answer 10

kinase associates with IL-1 receptor

Question 11

Pax5

Answer 11

B-cell specific protein expressed early during differentiation

Question 12

Tlr2

Answer 12

Recognized PAMS, mediates cytokine production

Question 13

Tnfrsf1b

Answer 13

binds TNF-alpha, mediates anti-apoptotic proteins