Day 3-Biopsy Flashcards
What is the time window for deciding to take a biopsy if a lesion does not go away?
10-14 days
______: fluid in or under the epithelium; a large blister
Bulla
______: dried or clotted serum protein on surface of skin or mucosa
Crust
______: a superficial ulcer or excoriation
Erosion
______: a circumscribed area of color change
without elevation
Macule
______: a large palpable mass, elevated above the epithelial surface
Nodule
_______: a small palpable mass, elevated above the epithelial surface
Papule
______ : a flat but elevated lesion
Plaque
______ : a cloudy or white vesicle filled with
pus
Pustule
______ : a macroscopic accumulation of keratin
Scale
______ : a loss of epithelium
Ulcer
_______ : a small loculation of fluid in or under the epithelium; a small blister
Vesicle
Indications for Biopsy: Any lesion that persists for more than ______ with no apparent etiologic basis
2 weeks
Indications for Biopsy: Any inflammatory lesion that does not respond to local treatment within ___-___ days
10-14 days
Indications for Biopsy: Hardest decision!! Persistent hyper______ changes in superficial tissue
keratotic
Indications for Biopsy: Lesions that interfere with local ______
FUNCTION
Indications for ________ : 1. Erythroplasia: totally red or speckled red and white 2. Ulceration 3. Duration: longer than 2 weeks 4. Growth rate: rapid 5. Bleeding 6. Induration 7. Fixation: feels attached to adjacent structures
Malignancy
_______: First described for detection of cervical malignancies: “pap” smear, “brush” biopsy kits available (CTX)
Cytology
One issue about cytology as a biopsy method is the unacceptable number of false ________
negatives
Who are the only people that can examine cytology biopsies?
pathologists!
What is the prime indication for the use of cytology?
When large areas of mucosal change must be monitored for dysplasia
**ANY radiolucency in the bone should be ________ before surgical intervention!

aspirated
________ biopsy: Samples only a particular or representative part (s) of the lesion
incisional
Incisional biopsy: If the lesion is TOO LARGE to excise without causing excess morbidity (>__ cm or in close proximity to vital anatomic structures.)
> 1 cm
Incisional Biopsy: Representative areas should be taken in ______ fashion
wedge
Incisional Biopsy: _______ tissue should be avoided
Necrotic
Incisional Biopsy: Include some ______ tissue at edge if possible
normal
Incisional Biopsy: Try to _____ specimen for pathologist.
orient
_______ biopsy: Implies removal of the entire lesion at the time the biopsy is performed
Excisional
Excisional biopsy: A perimeter of ______ tissue surrounding the lesion is also excised to ensure total removal
normal
Excisional biopsy: Good for smaller lesions ( __ cm or less) that appear to be ______
1cm …. benign
Biopsy technique: Specimen directly into 10% ______
formalin
Biopsy technique: ________ and _________ are hard to close
Hard palate….attached gingiva
