Day 3-Biopsy

Question 1

What is the time window for deciding to take a biopsy if a lesion does not go away?

Answer 1

10-14 days

Question 2

______: fluid in or under the epithelium; a large blister

Answer 2

Bulla

Question 3

______: dried or clotted serum protein on surface of skin or mucosa

Answer 3

Crust

Question 4

______: a superficial ulcer or excoriation

Answer 4

Erosion

Question 5

______: a circumscribed area of color change

without elevation

Answer 5

Macule

Question 6

______: a large palpable mass, elevated above the epithelial surface

Answer 6

Nodule

Question 7

_______: a small palpable mass, elevated above the epithelial surface

Answer 7

Papule

Question 8

______ : a flat but elevated lesion

Answer 8

Plaque

Question 9

______ : a cloudy or white vesicle filled with

pus

Answer 9

Pustule

Question 10

______ : a macroscopic accumulation of keratin

Answer 10

Scale

Question 11

______ : a loss of epithelium

Answer 11

Ulcer

Question 12

_______ : a small loculation of fluid in or under the epithelium; a small blister

Answer 12

Vesicle

Question 13

Indications for Biopsy: Any lesion that persists for more than ______ with no apparent etiologic basis

Answer 13

2 weeks

Question 14

Indications for Biopsy: Any inflammatory lesion that does not respond to local treatment within ___-___ days

Answer 14

10-14 days

Question 15

Indications for Biopsy: Hardest decision!! Persistent hyper______ changes in superficial tissue

Answer 15

keratotic

Question 16

Indications for Biopsy: Lesions that interfere with local ______

Answer 16

FUNCTION

Question 17

Indications for ________ : 1. Erythroplasia: totally red or speckled red and white 2. Ulceration 3. Duration: longer than 2 weeks 4. Growth rate: rapid 5. Bleeding 6. Induration 7. Fixation: feels attached to adjacent structures

Answer 17

Malignancy

Question 18

_______: First described for detection of cervical malignancies: “pap” smear, “brush” biopsy kits available (CTX)

Answer 18

Cytology

Question 19

One issue about cytology as a biopsy method is the unacceptable number of false ________

Answer 19

negatives

Question 20

Who are the only people that can examine cytology biopsies?

Answer 20

pathologists!

Question 21

What is the prime indication for the use of cytology?

Answer 21

When large areas of mucosal change must be monitored for dysplasia

Question 22

**ANY radiolucency in the bone should be ________ before surgical intervention!


Answer 22

aspirated

Question 23

________ biopsy: Samples only a particular or representative part (s) of the lesion

Answer 23

incisional

Question 24

Incisional biopsy: If the lesion is TOO LARGE to excise without causing excess morbidity (>__ cm or in close proximity to vital anatomic structures.)

Answer 24

> 1 cm

Question 25

Incisional Biopsy: Representative areas should be taken in ______ fashion

Answer 25

wedge

Question 26

Incisional Biopsy: _______ tissue should be avoided

Answer 26

Necrotic

Question 27

Incisional Biopsy: Include some ______ tissue at edge if possible

Answer 27

normal

Question 28

Incisional Biopsy: Try to _____ specimen for pathologist.

Answer 28

orient

Question 29

_______ biopsy: Implies removal of the entire lesion at the time the biopsy is performed

Answer 29

Excisional

Question 30

Excisional biopsy: A perimeter of ______ tissue surrounding the lesion is also excised to ensure total removal

Answer 30

normal

Question 31

Excisional biopsy: Good for smaller lesions ( __ cm or less) that appear to be ______

Answer 31

1cm …. benign

Question 32

Biopsy technique: Specimen directly into 10% ______

Answer 32

formalin

Question 33

Biopsy technique: ________ and _________ are hard to close

Answer 33

Hard palate….attached gingiva